Trial Outcomes & Findings for Health Effects of Increasing Muscle Activation While Sitting in Office Workers (NCT NCT02855541)

NCT ID: NCT02855541

Last Updated: 2018-11-13

Results Overview

2-h Post Oral Glucose Tolerance Test Blood Glucose

• Recruitment status: COMPLETED
• Study phase: NA
• Target enrollment: 25 participants
• Primary outcome timeframe: Measured after 4 weeks
• Results posted on: 2018-11-13

Participant Flow

Participant milestones

Measure	Cycling Intervention Participants will use a small cycling device (DeskCycle) at their workstation for 15 minutes every hour that they are at work. DeskCycle: A small cycling ergometer that can fit under a desk at the workplace.
Overall Study STARTED	25
Overall Study COMPLETED	21
Overall Study NOT COMPLETED	4

Reasons for withdrawal

Measure	Cycling Intervention Participants will use a small cycling device (DeskCycle) at their workstation for 15 minutes every hour that they are at work. DeskCycle: A small cycling ergometer that can fit under a desk at the workplace.
Overall Study Change in health status	2
Overall Study Withdrawal by Subject	2

Baseline Characteristics

Health Effects of Increasing Muscle Activation While Sitting in Office Workers

Baseline characteristics by cohort

Measure	Cycling Intervention n=21 Participants Participants will use a small cycling device (DeskCycle) at their workstation for 15 minutes every hour that they are at work. DeskCycle: A small cycling ergometer that can fit under a desk at the workplace.
Age, Continuous	34.8 years STANDARD_DEVIATION 9.9 • n=5 Participants
Sex: Female, Male Female	14 Participants n=5 Participants
Sex: Female, Male Male	7 Participants n=5 Participants
Ethnicity (NIH/OMB) Hispanic or Latino	2 Participants n=5 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	19 Participants n=5 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	0 Participants n=5 Participants
Region of Enrollment United States	21 participants n=5 Participants
Maximum Oxygen Consumption (VO2max)	2.07 L/min STANDARD_DEVIATION 0.44 • n=5 Participants
Blood Glucose	5.41 mmol/L STANDARD_DEVIATION 1.21 • n=5 Participants
Work Sitting	7.04 hours STANDARD_DEVIATION 0.78 • n=5 Participants
HDL Cholesterol	1.09 mmol/L STANDARD_DEVIATION 0.17 • n=5 Participants
LDL Cholesterol	2.50 mmol/L STANDARD_DEVIATION 0.67 • n=5 Participants
Triglycerides	1.16 mmol/L STANDARD_DEVIATION 0.64 • n=5 Participants
Lean Mass	47.8 kg STANDARD_DEVIATION 8.1 • n=5 Participants
Fat Mass	28.5 kg STANDARD_DEVIATION 13.0 • n=5 Participants
Systolic Blood Pressure	112.2 mmHg STANDARD_DEVIATION 10.3 • n=5 Participants

PRIMARY outcome

Timeframe: Measured after 4 weeks

2-h Post Oral Glucose Tolerance Test Blood Glucose

Outcome measures

Measure	Cycling Intervention n=21 Participants Participants will use a small cycling device (DeskCycle) at their workstation for 15 minutes every hour that they are at work. DeskCycle: A small cycling ergometer that can fit under a desk at the workplace.
Blood Glucose	5.60 mmol/L Standard Deviation 1.23

PRIMARY outcome

Timeframe: Measured after 4 weeks

Maximum oxygen consumption (VO2max) will be used to determine physical fitness

Outcome measures

Measure	Cycling Intervention n=21 Participants Participants will use a small cycling device (DeskCycle) at their workstation for 15 minutes every hour that they are at work. DeskCycle: A small cycling ergometer that can fit under a desk at the workplace.
Maximum Oxygen Consumption	2.17 L/min Standard Deviation 0.44

SECONDARY outcome

Timeframe: Measured after 4 weeks

Outcome measures

Measure	Cycling Intervention n=21 Participants Participants will use a small cycling device (DeskCycle) at their workstation for 15 minutes every hour that they are at work. DeskCycle: A small cycling ergometer that can fit under a desk at the workplace.
Systolic Blood Pressure	110.9 mmHg Standard Deviation 12.5

SECONDARY outcome

Timeframe: Measured after 4 weeks

Outcome measures

Measure	Cycling Intervention n=21 Participants Participants will use a small cycling device (DeskCycle) at their workstation for 15 minutes every hour that they are at work. DeskCycle: A small cycling ergometer that can fit under a desk at the workplace.
HDL Cholesterol	1.17 mmol/L Standard Deviation 0.24

SECONDARY outcome

Timeframe: Measured after 4 weeks

Outcome measures

Measure	Cycling Intervention n=21 Participants Participants will use a small cycling device (DeskCycle) at their workstation for 15 minutes every hour that they are at work. DeskCycle: A small cycling ergometer that can fit under a desk at the workplace.
LDL Cholesterol	2.60 mmol/L Standard Deviation 0.59

SECONDARY outcome

Timeframe: Measured after 4 weeks

Outcome measures

Measure	Cycling Intervention n=21 Participants Participants will use a small cycling device (DeskCycle) at their workstation for 15 minutes every hour that they are at work. DeskCycle: A small cycling ergometer that can fit under a desk at the workplace.
Triglycerides	1.17 mmol/L Standard Deviation 0.72

SECONDARY outcome

Timeframe: Measured after 4 weeks

Outcome measures

Measure	Cycling Intervention n=21 Participants Participants will use a small cycling device (DeskCycle) at their workstation for 15 minutes every hour that they are at work. DeskCycle: A small cycling ergometer that can fit under a desk at the workplace.
Lean Mass	47.4 kg Standard Deviation 8.3

SECONDARY outcome

Timeframe: Measured after 4 weeks

Outcome measures

Measure	Cycling Intervention n=21 Participants Participants will use a small cycling device (DeskCycle) at their workstation for 15 minutes every hour that they are at work. DeskCycle: A small cycling ergometer that can fit under a desk at the workplace.
Fat Mass	28.1 kg Standard Deviation 13.2

Adverse Events

Cycling Intervention

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

James Peterman, PhD

University of Colorado Boulder

Phone: 303-735-0358

Email: james.peterman@colorado.edu

Results disclosure agreements

• Principal investigator is a sponsor employee
• Publication restrictions are in place