Efficacy of a Brown Seaweed Powder for Glycemic Control

NCT ID: NCT02853916

Last Updated: 2017-10-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-08-31

Study Completion Date

2017-10-25

Brief Summary

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The objectives of this trial are to confirm efficacy in human of a brown seaweed powder and explore dose-response relationship by comparing two different doses.

The primary endpoint is incremental area under the curve (iAUC, mmol\*min/L) for blood glucose.

Detailed Description

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Conditions

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Blood Glucose

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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500 mg InSea2®

Group Type ACTIVE_COMPARATOR

500 mg InSea2®

Intervention Type DIETARY_SUPPLEMENT

250 mg InSea2®

Group Type ACTIVE_COMPARATOR

250 mg InSea2®

Intervention Type DIETARY_SUPPLEMENT

Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

Interventions

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500 mg InSea2®

Intervention Type DIETARY_SUPPLEMENT

250 mg InSea2®

Intervention Type DIETARY_SUPPLEMENT

Placebo

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Males and females aged between 18-45 y
* Normoglycemic (fasting blood glucose \<5.6 mmol/L)
* Body mass index (BMI) 18.5-29.9 kg/m2
* Able to consume bread products

Exclusion Criteria

* Fasting blood glucose \> 5.6 mmol/L
* Systolic blood pressure \> 140 mmHg and/or diastolic blood pressure \> 90 mmHg
* Previous history of cardiovascular disease, diabetes, liver or kidney disease, inflammatory bowel disease, celiac disease, short bowel syndrome, any malabsorptive syndrome, pancreatitis, gallbladder or biliary disease
* Presence of a gastrointestinal disorder within the past year
* Presence of major gastrointestinal surgeries
* Thyroid problems
* Smokers
* Consuming prescription or non-prescription drug, herbal or nutritional supplements known to affect blood glucose or that could affect the outcome of the study as per investigator's judgement
* Women that are currently pregnant or lactating, or not using an appropriate contraception method
* Excessive alcohol intake (more than 2 drinks per day or more than 9 drinks per week)
* Allergic to shellfish (crab) or molluscs
* Weight gain or loss of at least 10lbs in previous three months
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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innoVactiv Inc.

INDUSTRY

Sponsor Role collaborator

University of Manitoba

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Peter Jones, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Manitoba

Locations

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Richardson Centre for Functional Foods and Nutraceuticals

Winnipeg, Manitoba, Canada

Site Status

Countries

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Canada

Other Identifiers

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B2016:51

Identifier Type: -

Identifier Source: org_study_id