Motorized Platform and Autonomy Among the Frail and Pre-frail Older Adult (PLATAUTONOMIE)

NCT ID: NCT02850731

Last Updated: 2020-11-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2019-06-30

Study Completion Date

2022-12-31

Brief Summary

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Highly diversified programs of physical activity in older people have shown their effectiveness in terms of improving functional capacities. Only one of these programs, to date, has used a motorized platform. The motorized platform allows the use of sensorimotor programs adapted to this population. Thus, for the user, a combination of motor and sensory capacities necessary to actively control different positions as well as reactions to maintain balance are stimulated, and are as important as psychomotor capabilities to maintain autonomy and the fight against losing independence.

Demonstration of the effectiveness of this type of equipment would propose a new modality of physical activity adapted to this population. Use of this new equipment could allow the possibility of standardizing this activity, whilst continuing to individualize physical activity programs.

Two phases for each group (Intervention/Control):

Phase 1 (day 0 - week 6): 2x1 hour sessions per week using the Hu360® (Intervention group) or an adapted physical activity program (Control group) under supervision of a therapist who will adapt the program according to the progress of the patient, following a standardized procedure (exercises: postural/balance training, strength training for the legs/trunk and coordination and endurance activities) Phase 2 (week 6 - month 6): Physical activity program at home for both groups, performed independently.

Blinded evaluations will be performed at 6 weeks and at 6 months for each group.

The investigators hypothesis is that the use of the motorized platform will allow superior physical performance compared to a traditional physical activity program.

Detailed Description

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Background

The process of aging causes a progressive decline in functional capacities. Maintaining physical fitness appears to be an important factor to fight against frailty (40% more frailty in people \> 65 years old), a condition that causes loss of independence but that is clinically reversible.

Fragility is a condition that associates: slowed walking speed, sedentary lifestyle, weight loss, muscle weakness and low energy levels. It is therefore correlated with physical performance.

Purpose

A number of studies have demonstrated the benefit of physical activity in frail older people. Levels of adherence to physical activity programs are not well known but low adherence decreases the positive effects of the intervention. It seems therefore interesting to suggest another approach that integrates innovative technology (plate-forme Hu360®) that can improve the clinical condition of the frail older person, as well as levels of adherence.

Abstract

Highly diversified programs of physical activity in older people have shown their effectiveness in terms of improving functional capacities. Only one of these programs, to date, has used a motorized platform. The motorized platform allows the use of sensorimotor programs adapted to this population. Thus, for the user, a combination of motor and sensory capacities necessary to actively control different positions as well as reactions to maintain balance are stimulated, and are as important as psychomotor capabilities to maintain autonomy and the fight against losing independence.

Demonstration of the effectiveness of this type of equipment would propose a new modality of physical activity adapted to this population. Use of this new equipment could allow the possibility of standardizing this activity, whilst continuing to individualize physical activity programs.

Two phases for each group (Intervention/Control):

Phase 1 (day 0 - week 6): 2x1 hour sessions per week using the Hu360® (Intervention group) or an adapted physical activity program (Control group) under supervision of a therapist who will adapt the program according to the progress of the patient, following a standardized procedure (exercises: postural/balance training, strength training for the legs/trunk and coordination and endurance activities)

Phase 2 (week 6 - month 6): Physical activity program at home for both groups, performed independently.

Blinded evaluations will be performed at 6 weeks and at 6 months for each group.

The investigators hypothesis is that the use of the motorized platform will allow superior physical performance compared to a traditional physical activity program.

Statistical analysis

Data analysis will be realized, blinded to the treatment group. The analysis will be conducted with intention to treat.

The principal analysis will be made using a linear mixed model for repeated data, taking into account stratification factors (gender and class Score SPPB at baseline) by random effect, without imputation of missing data. An exploratory analysis will be conducted on the principal outcome measure using a linear mixed model for repeated data, taking into account stratification factors and some covariates that may change the effect of the intervention, such compliance.

Secondary outcome measures will be will be analysed in a similar manner by generalized linear mixed models. The tests will be bilateral. An error-correction modem of 5% will be considered during the analysis.

Conditions

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Fragility

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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plate-forme Hu360®

the innovative technology (plate-forme Hu360®) will be used in the experimental arm

Group Type EXPERIMENTAL

plate-forme Hu360®

Intervention Type DEVICE

the innovative technology (plate-forme Hu360®) will be used in the experimental arm

supervision by a therapist

an adapted physical activity program under supervision of a therapist

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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plate-forme Hu360®

the innovative technology (plate-forme Hu360®) will be used in the experimental arm

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subjects aged between 70-89 years old.
* Living at home
* Having at least one fragility criteria (from Fried's 5 criteria), which must include the sedentary criteria.
* Having a Score SPPB \<10
* Independent mobility
* MMSE score ≥18
* BMI between 18 and 40
* Informed consent to participate in a randomized control trial (physical activity using the motorized platform, Hu360® vs a traditional physical activity program).

Exclusion Criteria

* Severe cardiac problems
* Degenerative neurological conditions
* Hip/Knee joint replacement less than 6 months before the study.
* Psychotic disorders or bipolar disorder.
* Patients who already participate in a regular physical activity program or follow a rehabilitation program.
* Patients under legal protection and / or unable to give informed consent
* Already participating in a clinical trial or a study with a physical activity program.
Minimum Eligible Age

70 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Toulouse

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pierre Carette, PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Toulouse

Other Identifiers

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15 7841 16

Identifier Type: -

Identifier Source: org_study_id