Effects of Dexmedetomidine on Oxygenation and Lung Mechanics in Morbidly Obese Patients Undergoing Bariatric Operations
NCT ID: NCT02843698
Last Updated: 2017-08-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
42 participants
INTERVENTIONAL
2016-09-30
2017-08-26
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Dexmedetomidine group
Patients will receive either, Dexmedetomidine (Precedex, Hospira, Lake forest, IL, USA) in a dose of (1ug/Kg LBW) bolus followed by 0.5ug/Kg continuous infusion for one hour
Dexmedetomidine
Dexmedetomidine infusion was previously reported to improve oxygenation and lung dynamics in patients with obstructive lung diseases. In our study we are going to investigate its effect on oxygenation and lung dynamics in restrictive lung disease
Control group
Patients will receive normal saline
Normal saline
Normal saline
Interventions
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Dexmedetomidine
Dexmedetomidine infusion was previously reported to improve oxygenation and lung dynamics in patients with obstructive lung diseases. In our study we are going to investigate its effect on oxygenation and lung dynamics in restrictive lung disease
Normal saline
Normal saline
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* ِِِِArrhythmia
* Heart block
* Severe liver or kidney impairment.
18 Years
65 Years
ALL
No
Sponsors
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Cairo University
OTHER
Responsible Party
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Ahmed Hasanin
Lecturer of anesthesia and critical care medicine
Principal Investigators
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Ahmed Mukhtar, Professor
Role: STUDY_DIRECTOR
Head of research committee section in anesthesia department
Locations
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Cairo University
Cairo, , Egypt
Countries
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References
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Hasanin A, Taha K, Abdelhamid B, Abougabal A, Elsayad M, Refaie A, Amin S, Wahba S, Omar H, Kamel MM, Abdelwahab Y, Amin SM. Evaluation of the effects of dexmedetomidine infusion on oxygenation and lung mechanics in morbidly obese patients with restrictive lung disease. BMC Anesthesiol. 2018 Aug 14;18(1):104. doi: 10.1186/s12871-018-0572-y.
Other Identifiers
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N-12-2016
Identifier Type: -
Identifier Source: org_study_id
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