Trial Outcomes & Findings for Enhancing Treatment of Hoarding Disorder With Personalized In-Home Sorting and Decluttering Practice (NCT NCT02843308)
NCT ID: NCT02843308
Last Updated: 2025-11-21
Results Overview
The SI-R is a 23-item questionnaire with 3 sub-scales for difficulty discarding, excessive clutter, and compulsive acquisition. The total score ranges from 0 to 92. The greater the score, the more severe the hoarding symptoms. Total score higher than 41 shows significant difficulty with clutter. For the acquisition subscale, items 2 (reverse score), 9, 11, 14, 16, 18 and 21 are summed together. The subscale ranges from 0 to 28 and score greater than 13 indicates difficulty with excessive acquisition. For the difficulty discarding subscale, items 4(reverse score), 6, 7, 13, 17, 19, 23 are summed together. The subscale ranges from 0 to 28 and score greater than 13 indicates difficulty with discarding. For the clutter subscale, items 1, 3, 5, 8, 10, 12, 15, 20, 22 are summed together. The subscale ranges from 0 to 36 and score greater than 15 indicates difficulty with accumulated clutter. Response was defined as at least a 14 point change (pre-post) in the total score.
COMPLETED
NA
41 participants
Change from baseline (pre-treatment) to week 18 (post-treatment) the Immediate Treatment Arm/Group and change from baseline (pre-treatment at 18 weeks) to 36 weeks (post-treatment) for the Delayed Treatment Arm/Group
2025-11-21
Participant Flow
Participant milestones
| Measure |
Immediate Treatment
Facilitated group therapy with behavioral practice; 18 weeks
Facilitated group therapy with behavioral practice; 18 weeks: Facilitated group therapy for hoarding disorder with behavioral practice.
|
Delayed Treatment
Facilitated group therapy with behavioral practice; 18 weeks (after a 18-20 week delay)
Facilitated group therapy with behavioral practice; 18 weeks: Facilitated group therapy for hoarding disorder with behavioral practice.
|
|---|---|---|
|
Overall Study
STARTED
|
21
|
20
|
|
Overall Study
COMPLETED
|
18
|
19
|
|
Overall Study
NOT COMPLETED
|
3
|
1
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Enhancing Treatment of Hoarding Disorder With Personalized In-Home Sorting and Decluttering Practice
Baseline characteristics by cohort
| Measure |
Immediate Treatment
n=21 Participants
Facilitated group therapy with behavioral practice; 18 weeks
Facilitated group therapy with behavioral practice; 18 weeks: Facilitated group therapy for hoarding disorder with behavioral practice
|
Delayed Treatment
n=20 Participants
Facilitated group therapy with behavioral practice; 18 weeks (after a 18-20 week delay)
Facilitated group therapy with behavioral practice; 18 weeks: Facilitated group therapy for hoarding disorder with behavioral practice
|
Total
n=41 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
54.29 years
STANDARD_DEVIATION 12.06 • n=68 Participants
|
58.45 years
STANDARD_DEVIATION 8.41 • n=76 Participants
|
56.37 years
STANDARD_DEVIATION 10.24 • n=48 Participants
|
|
Sex: Female, Male
Female
|
15 Participants
n=68 Participants
|
12 Participants
n=76 Participants
|
27 Participants
n=48 Participants
|
|
Sex: Female, Male
Male
|
6 Participants
n=68 Participants
|
8 Participants
n=76 Participants
|
14 Participants
n=48 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
6 Participants
n=68 Participants
|
6 Participants
n=76 Participants
|
12 Participants
n=48 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
15 Participants
n=68 Participants
|
14 Participants
n=76 Participants
|
29 Participants
n=48 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=68 Participants
|
0 Participants
n=76 Participants
|
0 Participants
n=48 Participants
|
PRIMARY outcome
Timeframe: Change from baseline (pre-treatment) to week 18 (post-treatment) the Immediate Treatment Arm/Group and change from baseline (pre-treatment at 18 weeks) to 36 weeks (post-treatment) for the Delayed Treatment Arm/GroupThe SI-R is a 23-item questionnaire with 3 sub-scales for difficulty discarding, excessive clutter, and compulsive acquisition. The total score ranges from 0 to 92. The greater the score, the more severe the hoarding symptoms. Total score higher than 41 shows significant difficulty with clutter. For the acquisition subscale, items 2 (reverse score), 9, 11, 14, 16, 18 and 21 are summed together. The subscale ranges from 0 to 28 and score greater than 13 indicates difficulty with excessive acquisition. For the difficulty discarding subscale, items 4(reverse score), 6, 7, 13, 17, 19, 23 are summed together. The subscale ranges from 0 to 28 and score greater than 13 indicates difficulty with discarding. For the clutter subscale, items 1, 3, 5, 8, 10, 12, 15, 20, 22 are summed together. The subscale ranges from 0 to 36 and score greater than 15 indicates difficulty with accumulated clutter. Response was defined as at least a 14 point change (pre-post) in the total score.
Outcome measures
| Measure |
Immediate Treatment
n=18 Participants
Facilitated group therapy with behavioral practice; 18 weeks
Facilitated group therapy with behavioral practice; 18 weeks: Facilitated group therapy for hoarding disorder with behavioral practice
|
Delayed Treatment
n=19 Participants
Facilitated group therapy with behavioral practice; 18 weeks (after a 18-20 week delay)
Facilitated group therapy with behavioral practice; 18 weeks: Facilitated group therapy for hoarding disorder with behavioral practice
|
|---|---|---|
|
Number of Patients Who Met and Exceeded Response Criteria of the Saving Inventory-Revised (SI-R)
|
9 Participants
|
13 Participants
|
Adverse Events
Immediate Treatment
Delayed Treatment
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Carolyn Rodriguez, MD, PhD
Stanford University School of Medicine
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place