Assessment of Response to Neo-adjuvant Chemotherapy for Patients With a Locally Advanced Breast Cancer With 3D Elastography (Shear Wave), NEOELASTO
NCT ID: NCT02834494
Last Updated: 2025-11-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
140 participants
INTERVENTIONAL
2016-02-22
2020-09-09
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
OTHER
NONE
Study Groups
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3D Shear Wave Elastography (SWE)
3D Shear Wave Elastography (SWE)
Ultrasound imaging with Elastography will be performed at the inclusion (T0), after course 1 and course 2 respectively with anthracyclines, at the end of anthracycline treatment and at the end of taxane treatment.
Biopsy
Optional biopsy of breast tumor under neoadjuvant chemotherapy after the course 2 of anthracycline.
Interventions
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3D Shear Wave Elastography (SWE)
Ultrasound imaging with Elastography will be performed at the inclusion (T0), after course 1 and course 2 respectively with anthracyclines, at the end of anthracycline treatment and at the end of taxane treatment.
Biopsy
Optional biopsy of breast tumor under neoadjuvant chemotherapy after the course 2 of anthracycline.
Eligibility Criteria
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Inclusion Criteria
* Neo-adjuvant chemotherapy decided.(Anthracyclines, taxanes and, for tumors overexpressing human epidermal growth factor receptor 2 (HER2) protein, targeted recombinant humanized monoclonal antibodies)
* Index tumor whose dimensions are between 10 to 50 mm. Multifocality, and/or multicentricity and/or bilaterality accepted (maximum 2 tumors by breast et tumors well differentiated from each other).
* Patients aged at least 18 years old at diagnosis
* Full results conventional breast exams available and no reason to achieve MRI breast exam
* Patient explanation given and consent information signed
Exclusion Criteria
* Personal history of ipsilateral breast cancer (ipsilateral recurrence or second cancer in the same breast).
* Patient carrier of cosmetic breast implants
* Person deprived of liberty or under guardianship
* Contraindication for receiving neo-adjuvant chemotherapy for any medical reason
* Inability to submit to medical monitoring of the trial for reasons of geography, social or psychological.
18 Years
ALL
No
Sponsors
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Institut Curie
OTHER
Responsible Party
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Locations
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Institut Curie Paris
Paris, , France
Countries
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Other Identifiers
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IC 2015-07
Identifier Type: -
Identifier Source: org_study_id
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