Evaluation of the Physiopathological Phenomena and the Haemodynamic and Cerebral Metabolic Effects From Semi-seated Position to Lying Position in Patients With Brain Trauma

NCT ID: NCT02832908

Last Updated: 2016-07-14

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 90 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2014-12-31
• Study Completion Date: 2016-12-31

Brief Summary

Brain trauma is an important burden in traumatologic intensive care. In these patients the treatment is guided by a cluster of multimodal monitoring parameters. Despite this it is difficult to assess the actual physiopathologic status of the brain. Changing the position of these patients (semi-seated to lying position) causes changes in the hémodynamics brain conditions, so in monitoring parameters . The analysis of these changes can givr us valuable clinically informations.

Detailed Description

Severe brain trauma (CGS < 8 ) are included. PIC, PA, PVC, EKG, airway pressure, SjO2 and NIRSS are continuously monitored.

The patients are in semi seated (30°) position. Once a day they are in supine (0°) for 30 minutes. We record every parameters before and at the end of this supine period.

After time domain and frequency domain signal processing, this parameters are compared to deduct clinical relevant conclusions.

Conditions

Traumatic Brain Injury

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Blinding Strategy: NONE

Study Groups

Patients + parents

Patients with severe head trauma

Group Type: OTHER

Change from semi-seated position to supine

Intervention Type: OTHER

from semi-seated position (30°) to lying position

Interventions

Change from semi-seated position to supine

from semi-seated position (30°) to lying position

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• patients with a severe head trauma estimated by the Glasgow Coma Scale and by the Glasgow Outcome Scale
• age > 18

Exclusion Criteria

• Other neurological pathology

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital, Montpellier

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Hôpital Lapeyronie - Département Anesthésie Réanimation A

Montpellier, , France

Site Status: RECRUITING

Countries

France

Central Contacts

Jean Paul ROUSTAN, MD

Role: CONTACT

jp-roustan@chu-montpellier.fr

0467338256

Facility Contacts

Jean Paul ROUSTAN, MD

Role: primary

jp-roustan@chu-montpellier.fr

04 67 33 82 56

References

Dagod G, Roustan JP, Bringuier-Branchereau S, Ridolfo J, Martinez O, Capdevila X, Charbit J. Effect of a temporary lying position on cerebral hemodynamic and cerebral oxygenation parameters in patients with severe brain trauma. Acta Neurochir (Wien). 2021 Sep;163(9):2595-2602. doi: 10.1007/s00701-021-04851-x. Epub 2021 Jul 8.

Reference Type: DERIVED

PMID: 34236525 (View on PubMed)

Other Identifiers

9413

Identifier Type: -

Identifier Source: org_study_id