A Study of Structure and Function of Radial Artery After Transradial Coronary Intervention

NCT ID: NCT02831322

Last Updated: 2023-02-15

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 600 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-07-10
• Study Completion Date: 2017-10-01

Brief Summary

Several approaches have been proposed to reduce the risk of RAO, including anticoagulation, immediate postprocedural sheath removal, and a small sheath/radial artery ratio. Doppler ultrasound examination showed that interrupted blood flow in RA tend to occur in the proximal end rather than distal part of the artery,which was ignored by a majority of interventional cardiologists. Different insights into occlusion location may lead to different options of sheath materials, models, catheters and puncture access. Thus, the investigators designed this present study to explore the reason of radial artery endothelial dysfuction and damage and occlusion location by flow-mediated dilation (FMD) to determine the suitable method to reduce occlusion risk during TRI.

Conditions

Intervention; Transradial

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

radial artery occlusion

Radial artery occlusion was the absence of a flow signal by Doppler ultrasound examination.

Group Type: EXPERIMENTAL

Percutaneous coronary intervention

Intervention Type: PROCEDURE

Percutaneous coronary intervention was a nonsurgical technique for treating obstructive coronary artery disease

radial artery normal

Radial artery normal was blood flow signal by Doppler ultrasound

Group Type: OTHER

Percutaneous coronary intervention

Intervention Type: PROCEDURE

Percutaneous coronary intervention was a nonsurgical technique for treating obstructive coronary artery disease

Interventions

Percutaneous coronary intervention

Percutaneous coronary intervention was a nonsurgical technique for treating obstructive coronary artery disease

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• admitted for transradial catheterization.

Exclusion Criteria

• femoral access, arterial circulatory disease, pathological Allen tests, decompensated heart failure, chronic renal failure

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

The First Hospital of Qinhuangdao

OTHER_GOV

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Qingsheng wang

Qinhuangdao, Hebei, China

Countries

China

Other Identifiers

21735

Identifier Type: -

Identifier Source: org_study_id