Evaluation of Monitoring Neuromuscular Blockade the Flexor Hallucis Compared to the Adductor Pollicis

NCT ID: NCT02825121

Last Updated: 2017-10-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-02-29

Study Completion Date

2017-09-30

Brief Summary

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Current guidelines recommend monitoring of neuromuscular blockade at the adductor pollicis by stimulation of the ulnar nerve at the wrist.

However, in certain situations (laparoscopic surgery, cranial surgery or surgical comfort, arterial catheterization), it is impossible to access the patient's wrists, delaying monitoring, antagonizing the neuromuscular block, the emergence from anesthesia and patient extubation , leading in some cases to single injections lack of control of the reversal of the patient.

To overcome these technical difficulties, a group nerve / muscle looks interesting and often easily accessible to the anesthesiologist.

The stimulation of the posterior tibial nerve can observe a response to the flexor hallucis brevis muscle and allows quick access to monitoring the reversal before the end of the intervention.

The primary outcome was to compare the speed of recovery from neuromuscular block flexor hallux versus that of the adductor pollicis.

The secondary objective was to compare the speed of installation of deep neuromuscular block flexor hallucis versus that of the adductor pollicis.

This is a prospective, exploratory, uncontrolled, single-center for routine care.

Are included all aged patients over 18 years, ASA I or II, without guardianship, having no known allergy to Atracurium, without neuromyopathy known, emergency surgery or full stomach, predictable difficult intubation .

Detailed Description

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Conditions

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Observation of Neuromuscular Block Flexor Hallucis Adductor Pollicis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Monitoring Neuromuscular Blockade

Monitoring Neuromuscular Blockade the Flexor Hallucis and adductor of the thumb.

Group Type EXPERIMENTAL

Monitoring Neuromuscular Blockade the Flexor Hallucis

Intervention Type DEVICE

Monitoring Neuromuscular Blockade adductor of the thumb.

Intervention Type DEVICE

Interventions

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Monitoring Neuromuscular Blockade the Flexor Hallucis

Intervention Type DEVICE

Monitoring Neuromuscular Blockade adductor of the thumb.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* over 18 years
* Any elective surgery with single or multiple injection Atracurium for which hand and foot are accessible at the same time.
* ASA I or II patients
* free subject, without guardianship or subordination
* No opposition given by the patient after information

Exclusion Criteria

* under 18 years
* known neuromyopathy
* Diabetics
* Emergency surgery and a full stomach
* predictable difficult intubation
* Pregnant or breastfeeding women, women of childbearing age who do not have effective contraception
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Poitiers University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Poitiers Universitary Hospital

Poitiers, , France

Site Status

Countries

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France

References

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Le Merrer M, Frasca D, Dupuis M, Debaene B, Boisson M. A comparison between the flexor hallucis brevis and adductor pollicis muscles in atracurium-induced neuromuscular blockade using acceleromyography: A prospective observational study. Eur J Anaesthesiol. 2020 Jan;37(1):38-43. doi: 10.1097/EJA.0000000000001090.

Reference Type DERIVED
PMID: 31592900 (View on PubMed)

Other Identifiers

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CURHATOF

Identifier Type: -

Identifier Source: org_study_id