Trial Outcomes & Findings for Estimating Blood Concentrations of Anaesthetics During One-Lung Ventilation (OLV) (NCT NCT02821455)

Results Overview

The significance of the correlation between blood and end-tidal isoflurane or sevoflurane concentration during one-lung ventilation

Recruitment status

COMPLETED

Target enrollment

19 participants

Primary outcome timeframe

10 minutes after start of one-lung ventilation

Results posted on

2018-08-02

Participant Flow

Participant milestones

Participant milestones
Measure	Lung Surgery With One-Lung Ventilation A single cohort of patients undergoing one-lung ventilation during lung surgery Lung Surgery with One-Lung Ventilation: A single cohort of patients undergoing one-lung ventilation during lung surgery
Overall Study STARTED	19
Overall Study COMPLETED	19
Overall Study NOT COMPLETED	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Lung Surgery With One-Lung Ventilation n=19 Participants A single cohort of patients undergoing one-lung ventilation during lung surgery Lung Surgery with One-Lung Ventilation: A single cohort of patients undergoing one-lung ventilation during lung surgery
Age, Continuous	67.2 years STANDARD_DEVIATION 9.8 • n=19 Participants
Sex: Female, Male Female	10 Participants n=19 Participants
Sex: Female, Male Male	9 Participants n=19 Participants

PRIMARY outcome

Timeframe: 10 minutes after start of one-lung ventilation

The significance of the correlation between blood and end-tidal isoflurane or sevoflurane concentration during one-lung ventilation

Outcome measures

Outcome measures
Measure	Lung Surgery With One-Lung Ventilation n=19 Participants A single cohort of patients undergoing one-lung ventilation during lung surgery Lung Surgery with One-Lung Ventilation: A single cohort of patients undergoing one-lung ventilation during lung surgery
Correlation Between Blood and End-tidal Isoflurane or Sevoflurane Concentration During One-lung Ventilation	0.0807 Correlation coefficient

SECONDARY outcome

Timeframe: 10 minutes after start of one-lung ventilation

Population: Data not collected due to insufficient use of Bispectral Index Monitors and temperature monitors by anaesthetists responsible for the study participants at the study site.

The significance of the correlation between BIS and end-tidal isoflurane or sevoflurane concentration during one-lung ventilation.

Outcome measures

Outcome data not reported

Adverse Events

Lung Surgery With One-Lung Ventilation

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

E Alexandra Page

University of Edinburgh

Phone: 7938645122

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place