Comparing Patient-Centered Outcomes After Treatment for Uterine Fibroids

NCT ID: NCT02819609

Last Updated: 2016-06-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

12234 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-11-30

Study Completion Date

2015-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this observational, retrospective database study of patients with uterine fibroids is to compare the durability of symptom relief after uterus-conserving treatments for symptomatic fibroids in terms of incidence of, and time to, new or recurrent symptoms and subsequent procedures and evaluate the effect stakeholder participation had on the research process.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Uterine Fibroids

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Myomectomy

Women with uterine fibroids who underwent myomectomy as their index procedure as part of their routine clinical care

myomectomy

Intervention Type PROCEDURE

Myomectomy as part of routine clinical care

Endometrial ablation

Women with uterine fibroids who underwent endometrial ablation as their index procedure as part of their routine clinical care

endometrial ablation

Intervention Type PROCEDURE

Endometrial ablation as part of routine clinical care

Uterine artery embolization

Women with uterine fibroids who underwent uterine artery embolization as their index procedure as part of their routine clinical care

uterine artery embolization

Intervention Type PROCEDURE

Uterine artery embolization as part of routine clinical care

MRI-guided focused ultrasound ablation

Women with uterine fibroids who underwent MRI-guided focused ultrasound ablation as their index procedure as part of their routine clinical care

MRI-guided focused ultrasound ablation

Intervention Type PROCEDURE

MRI-guided focused ultrasound ablation as part of routine clinical care

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

myomectomy

Myomectomy as part of routine clinical care

Intervention Type PROCEDURE

endometrial ablation

Endometrial ablation as part of routine clinical care

Intervention Type PROCEDURE

uterine artery embolization

Uterine artery embolization as part of routine clinical care

Intervention Type PROCEDURE

MRI-guided focused ultrasound ablation

MRI-guided focused ultrasound ablation as part of routine clinical care

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Female patients with a diagnosis of uterine fibroids at any time and at least 1 office visit during study time period
* At least 1 of the procedures of interest occurring between January 1, 2005 - December 31, 2011
* ≥ 18 years and \< 55 years of age at the index date

Exclusion Criteria

* Patients with a diagnosis of gynecologic cancer (ovarian, uterine, cervical)
* First recorded diagnosis of uterine fibroids occurring beyond four weeks after the Index Date ONLY for patients who underwent endometrial ablation or hysterectomy
* Patients with a record of any procedures of interest occurring before January 1, 2005
Minimum Eligible Age

18 Years

Maximum Eligible Age

54 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Center for Medical Technology Policy

UNKNOWN

Sponsor Role collaborator

Duke University

OTHER

Sponsor Role collaborator

Quintiles, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Priscilla Velentgas

Senior Director of Epidemiology and Health Outcomes

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CE-12-11-4430

Identifier Type: -

Identifier Source: org_study_id