Integral Strategy to Supportive Care in Breast Cancer Patients

NCT ID: NCT02817724

Last Updated: 2017-10-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-07-31

Study Completion Date

2019-07-31

Brief Summary

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The purpose of this study is to determine if it is better an integral strategy, with a m-health system, when used in addition to a supervised treatment, versus the use of the m-health system alone, to improve the immediate and long-term Quality of Life of breast cancer survivors.

Detailed Description

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Background: Technological support using e-health mobile applications (m-health) is a promising strategy to improve the adherence to healthy lifestyles in breast cancer survivors (excess in energy intake or low physical activity are determinants of the risk of recurrence, second cancers and cancer mortality). Moreover, cancer rehabilitation programs supervised by health professionals are needed due to the inherent characteristics of these breast cancer patients. Our main objective is to compare the clinical efficacy of a m-health lifestyle intervention system alone versus an integral strategy to improve Quality of Life (QoL) in breast cancer survivors.

Methods: This therapeutic superiority study will use a two-arm, assessor blinded parallel randomized clinical trial (RCT) design. Women will be eligible if: they are diagnosed of stage I, II or III-A breast cancer; are between 25 and 75 years old; have a Body Mass Index \> 25kg/m2; they have basic ability to use mobile apps; they had completed adjuvant therapy except for hormone therapy; and they have some functional shoulder limitations. Participants will be randomized to one of the following groups: integral group will use a mobile application (BENECA APP) and will receive a supervised rehabilitation (8-weeks); m-health group will use the BENECA app for 8-weeks. Study endpoints will be assessed after 8 weeks and 24 weeks. The primary outcome will be QoL measured by The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core and breast module. The secondary outcomes: body composition; upper-body functionality (handgrip, Disability of the Arm, Shoulder and Hand questionnaire, goniometry); cognitive function (Wechsler Adult Intelligence Scale, Trial Making Test); anxiety and depression (Hospital Anxiety and Depression Scale); and accelerometer.

Discussion: This study has been designed to seek to address the new needs for support and treatment of breast cancer survivors, reflecting the emerging need to merge new low cost treatment options with much-needed involvement of health professionals in this type of patients.

Conditions

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Breast Neoplasms

Keywords

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Breast Neoplasms survivor occupational therapy mobile applications Quality of Life

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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m-Health group

BENECA System: The m-health group will use the BENECA app for 8 weeks.

Group Type ACTIVE_COMPARATOR

BENECA System

Intervention Type DEVICE

BENECA System is a mobile application whit aims to recover a healthy lifestyle in breast cancer survivors (in terms of energy balance: physical activity and dietary).

Integral Group

BENECA System and Supervised-occupational therapy program: The integral groups will use the BENECA app and they will receive a face-to-face occupational therapy rehabilitation program for 8 weeks.

Group Type EXPERIMENTAL

BENECA System

Intervention Type DEVICE

BENECA System is a mobile application whit aims to recover a healthy lifestyle in breast cancer survivors (in terms of energy balance: physical activity and dietary).

Supervised-occupational therapy program

Intervention Type OTHER

It is a comprehensive program that covers most of the physical, cognitive and emotional needs of these patients after oncology treatment from occupational therapy perspective.

Interventions

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BENECA System

BENECA System is a mobile application whit aims to recover a healthy lifestyle in breast cancer survivors (in terms of energy balance: physical activity and dietary).

Intervention Type DEVICE

Supervised-occupational therapy program

It is a comprehensive program that covers most of the physical, cognitive and emotional needs of these patients after oncology treatment from occupational therapy perspective.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of stage I, II or IIIA breast cancer.
* Overweight or obese, according to the Spanish Society for the Study of Obesity.
* Basic ability to use mobile apps or living with someone who has this ability.
* Medical clearance of participants.
* Completion of adjuvant therapy except for hormone therapy.
* Some functional or Range of Motion (ROM) limitations measures by goniometry and the DASH Questionnaire.
* Have signed informed consent.

Exclusion Criteria

* History of cancer recurrence.
* Chronic disease or orthopedic issues that would interfere with the ability to participate in the rehabilitation program.
* Uncontrolled hypertension (diastolic pressure \> 95mm Hg).
Minimum Eligible Age

25 Years

Maximum Eligible Age

75 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Carlos III Health Institute

OTHER_GOV

Sponsor Role collaborator

Universidad de Granada

OTHER

Sponsor Role lead

Responsible Party

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Manuel Arroyo Morales

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Manuel Arroyo-Morales, PhD

Role: STUDY_DIRECTOR

Deparment of physiotherapy, Faculty of Health Sciences, University of Granada

Locations

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Faculty of Health Sciences. University of Granada

Granada, , Spain

Site Status

Countries

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Spain

References

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Lozano-Lozano M, Galiano-Castillo N, Martin-Martin L, Pace-Bedetti N, Fernandez-Lao C, Arroyo-Morales M, Cantarero-Villanueva I. Monitoring Energy Balance in Breast Cancer Survivors Using a Mobile App: Reliability Study. JMIR Mhealth Uhealth. 2018 Mar 27;6(3):e67. doi: 10.2196/mhealth.9669.

Reference Type DERIVED
PMID: 29588273 (View on PubMed)

Lozano-Lozano M, Martin-Martin L, Galiano-Castillo N, Alvarez-Salvago F, Cantarero-Villanueva I, Fernandez-Lao C, Sanchez-Salado C, Arroyo-Morales M. Integral strategy to supportive care in breast cancer survivors through occupational therapy and a m-health system: design of a randomized clinical trial. BMC Med Inform Decis Mak. 2016 Nov 25;16(1):150. doi: 10.1186/s12911-016-0394-0.

Reference Type DERIVED
PMID: 27887610 (View on PubMed)

Other Identifiers

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PI14/01627

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

FPU14/01069

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

PI14/01627

Identifier Type: -

Identifier Source: org_study_id