Efficacy of Ginger in the Prevention of Abdominal Distention in Post Cesarean Section Patient

NCT ID: NCT02809027

Last Updated: 2020-07-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

178 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-06-01

Study Completion Date

2017-06-30

Brief Summary

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The purpose of this study is to determine ginger is effective in the prevention of abdominal distention in post Cesarean section patient.

Detailed Description

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Conditions

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Post Cesarean Section Patient

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Ginger

Ginger capsule (500 mg), oral form, 2 capsules 3 time after meal for 3 days

Group Type ACTIVE_COMPARATOR

Ginger

Intervention Type DRUG

Placebo

Placebo capsule, oral form, 2 capsules 3 time after meal for 3 days

Group Type SHAM_COMPARATOR

Placebo

Intervention Type DRUG

Interventions

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Ginger

Intervention Type DRUG

Placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Post cesarean section women

Exclusion Criteria

* allergic to ginger
* time of cesarean section more than 1 hour
* perform another operation such as appendectomy, cystectomy
* former use carminative drugs
* already have abdominal distention
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Chulalongkorn University

OTHER

Sponsor Role lead

Responsible Party

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Vorapong Phupong

Professor Vorapong Phupong

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Vorapong Phupong, M.D.

Role: STUDY_DIRECTOR

Chulalongkorn University

References

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Carroll J, Alavi K. Pathogenesis and management of postoperative ileus. Clin Colon Rectal Surg. 2009 Feb;22(1):47-50. doi: 10.1055/s-0029-1202886.

Reference Type BACKGROUND
PMID: 20119556 (View on PubMed)

Chaiyakunapruk N, Kitikannakorn N, Nathisuwan S, Leeprakobboon K, Leelasettagool C. The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis. Am J Obstet Gynecol. 2006 Jan;194(1):95-9. doi: 10.1016/j.ajog.2005.06.046.

Reference Type BACKGROUND
PMID: 16389016 (View on PubMed)

O'Hara M, Kiefer D, Farrell K, Kemper K. A review of 12 commonly used medicinal herbs. Arch Fam Med. 1998 Nov-Dec;7(6):523-36. doi: 10.1001/archfami.7.6.523.

Reference Type BACKGROUND
PMID: 9821826 (View on PubMed)

Ushiroyama T, Sakuma K, Souen H, Nakai G, Morishima S, Yamashita Y, Kamegai H. Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in), a traditional herbal medicine, stimulates lactation with increase in secretion of prolactin but not oxytocin in the postpartum period. Am J Chin Med. 2007;35(2):195-202. doi: 10.1142/S0192415X07004734.

Reference Type BACKGROUND
PMID: 17436360 (View on PubMed)

Gibstein A, Cooper JJ, Wisot AL, Rosenthal AH. Prevention of postoperative abdominal distention and discomfort with simethicone. Obstet Gynecol. 1971 Sep;38(3):386-90. No abstract available.

Reference Type RESULT
PMID: 4937581 (View on PubMed)

Hu ML, Rayner CK, Wu KL, Chuah SK, Tai WC, Chou YP, Chiu YC, Chiu KW, Hu TH. Effect of ginger on gastric motility and symptoms of functional dyspepsia. World J Gastroenterol. 2011 Jan 7;17(1):105-10. doi: 10.3748/wjg.v17.i1.105.

Reference Type RESULT
PMID: 21218090 (View on PubMed)

Other Identifiers

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114/59

Identifier Type: -

Identifier Source: org_study_id

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