Trial Outcomes & Findings for Educational Intervention to Improve HPV Vaccination Decision Quality (NCT NCT02797054)

NCT ID: NCT02797054

Last Updated: 2018-09-21

Results Overview

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

1205 participants

Primary outcome timeframe

1 day

Results posted on

2018-09-21

Participant Flow

Participant milestones

Participant milestones
Measure
Tailored Intervention
Intervention: tailored educational materials. In this arm, participants will complete a baseline survey on an iPad, view a series of educational webpages on the iPad, and complete a brief post intervention survey. Tailored educational materials: The tailored intervention will use participants' baseline survey responses to generate tailored educational messages about the HPV vaccine. These educational messages will reflect the top concerns indicated by the participant about the HPV vaccine. Additional tailoring will occur in the form of images matched to self-reported race and age, and using participants' first name in the information presented.
Untailored Intervention
Intervention: untailored educational materials. In this arm, patients will view educational information on the iPad that is not responsive to their baseline questionnaire answers. Untailored educational materials: The untailored intervention will present educational information on the iPad that is not responsive to participants' baseline questionnaire answers and instead is derived directly from the HPV "Vaccine Information Sheet" that has been created by the Centers for Disease Control and Prevention.
Usual Care
Intervention: usual care as experienced during appointment with primary care provider. Participants in the usual care arm will not view any educational materials or complete the baseline survey. Usual care: Those in the usual care arm will be provided with a paper version of the Post Intervention Survey. This will be provided to participants after their clinic visit is completed.
Post-test
STARTED
387
383
435
Post-test
COMPLETED
380
372
87
Post-test
NOT COMPLETED
7
11
348
Follow-up
STARTED
387
383
435
Follow-up
COMPLETED
178
155
150
Follow-up
NOT COMPLETED
209
228
285

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Educational Intervention to Improve HPV Vaccination Decision Quality

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Tailored Intervention
n=387 Participants
Intervention: tailored educational materials. In this arm, participants will complete a baseline survey on an iPad, view a series of educational webpages on the iPad, and complete a brief post intervention survey. Tailored educational materials: The tailored intervention will use participants' baseline survey responses to generate tailored educational messages about the HPV vaccine. These educational messages will reflect the top concerns indicated by the participant about the HPV vaccine. Additional tailoring will occur in the form of images matched to self-reported race and age, and using participants' first name in the information presented.
Untailored Intervention
n=383 Participants
Intervention: untailored educational materials. In this arm, patients will view educational information on the iPad that is not responsive to their baseline questionnaire answers. Untailored educational materials: The untailored intervention will present educational information on the iPad that is not responsive to participants' baseline questionnaire answers and instead is derived directly from the HPV "Vaccine Information Sheet" that has been created by the Centers for Disease Control and Prevention.
Usual Care
n=435 Participants
Intervention: usual care as experienced during appointment with primary care provider. Participants in the usual care arm will not view any educational materials or complete the baseline survey. Usual care: Those in the usual care arm will be provided with a paper version of the Post Intervention Survey. This will be provided to participants after their clinic visit is completed.
Total
n=1205 Participants
Total of all reporting groups
Age, Customized
Age
32.01 Years
n=5 Participants
31.18 Years
n=7 Participants
31.60 Years
n=5 Participants
31.60 Years
n=4 Participants
Sex: Female, Male
Female
386 Participants
n=5 Participants
382 Participants
n=7 Participants
434 Participants
n=5 Participants
1202 Participants
n=4 Participants
Sex: Female, Male
Male
1 Participants
n=5 Participants
1 Participants
n=7 Participants
1 Participants
n=5 Participants
3 Participants
n=4 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
349 Participants
n=5 Participants
342 Participants
n=7 Participants
392 Participants
n=5 Participants
1083 Participants
n=4 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
36 Participants
n=5 Participants
41 Participants
n=7 Participants
40 Participants
n=5 Participants
117 Participants
n=4 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
2 Participants
n=5 Participants
0 Participants
n=7 Participants
3 Participants
n=5 Participants
5 Participants
n=4 Participants
Race/Ethnicity, Customized
Race · White
88 Participants
n=5 Participants
98 Participants
n=7 Participants
105 Participants
n=5 Participants
291 Participants
n=4 Participants
Race/Ethnicity, Customized
Race · African American
4 Participants
n=5 Participants
1 Participants
n=7 Participants
2 Participants
n=5 Participants
7 Participants
n=4 Participants
Race/Ethnicity, Customized
Race · Asian
2 Participants
n=5 Participants
1 Participants
n=7 Participants
0 Participants
n=5 Participants
3 Participants
n=4 Participants
Race/Ethnicity, Customized
Race · American Indian
6 Participants
n=5 Participants
6 Participants
n=7 Participants
6 Participants
n=5 Participants
18 Participants
n=4 Participants
Race/Ethnicity, Customized
Race · Other
285 Participants
n=5 Participants
277 Participants
n=7 Participants
319 Participants
n=5 Participants
881 Participants
n=4 Participants
Race/Ethnicity, Customized
Race · Unknown
2 Participants
n=5 Participants
0 Participants
n=7 Participants
3 Participants
n=5 Participants
5 Participants
n=4 Participants

PRIMARY outcome

Timeframe: 1 day

Outcome measures

Outcome measures
Measure
Tailored Intervention
n=380 Participants
Intervention: tailored educational materials. In this arm, participants will complete a baseline survey on an iPad, view a series of educational webpages on the iPad, and complete a brief post intervention survey. Tailored educational materials: The tailored intervention will use participants' baseline survey responses to generate tailored educational messages about the HPV vaccine. These educational messages will reflect the top concerns indicated by the participant about the HPV vaccine. Additional tailoring will occur in the form of images matched to self-reported race and age, and using participants' first name in the information presented.
Untailored Intervention
n=372 Participants
Intervention: untailored educational materials. In this arm, patients will view educational information on the iPad that is not responsive to their baseline questionnaire answers. Untailored educational materials: The untailored intervention will present educational information on the iPad that is not responsive to participants' baseline questionnaire answers and instead is derived directly from the HPV "Vaccine Information Sheet" that has been created by the Centers for Disease Control and Prevention.
Usual Care
n=87 Participants
Intervention: usual care as experienced during appointment with primary care provider. Participants in the usual care arm will not view any educational materials or complete the baseline survey. Usual care: Those in the usual care arm will be provided with a paper version of the Post Intervention Survey. This will be provided to participants after their clinic visit is completed.
Percent of Participants - Who Agreed They Felt Sure About the Best Choice Regarding the HPV Vaccine at Post-intervention
94 Percent of participants
95 Percent of participants
89 Percent of participants

PRIMARY outcome

Timeframe: 1 day

Outcome measures

Outcome measures
Measure
Tailored Intervention
n=380 Participants
Intervention: tailored educational materials. In this arm, participants will complete a baseline survey on an iPad, view a series of educational webpages on the iPad, and complete a brief post intervention survey. Tailored educational materials: The tailored intervention will use participants' baseline survey responses to generate tailored educational messages about the HPV vaccine. These educational messages will reflect the top concerns indicated by the participant about the HPV vaccine. Additional tailoring will occur in the form of images matched to self-reported race and age, and using participants' first name in the information presented.
Untailored Intervention
n=372 Participants
Intervention: untailored educational materials. In this arm, patients will view educational information on the iPad that is not responsive to their baseline questionnaire answers. Untailored educational materials: The untailored intervention will present educational information on the iPad that is not responsive to participants' baseline questionnaire answers and instead is derived directly from the HPV "Vaccine Information Sheet" that has been created by the Centers for Disease Control and Prevention.
Usual Care
n=87 Participants
Intervention: usual care as experienced during appointment with primary care provider. Participants in the usual care arm will not view any educational materials or complete the baseline survey. Usual care: Those in the usual care arm will be provided with a paper version of the Post Intervention Survey. This will be provided to participants after their clinic visit is completed.
Percent of Participants Who Agreed They Knew Enough About the Risks and Benefits of the HPV Vaccine at Post-intervention
75 Percent of participants
77 Percent of participants
69 Percent of participants

PRIMARY outcome

Timeframe: 1 day

Outcome measures

Outcome measures
Measure
Tailored Intervention
n=380 Participants
Intervention: tailored educational materials. In this arm, participants will complete a baseline survey on an iPad, view a series of educational webpages on the iPad, and complete a brief post intervention survey. Tailored educational materials: The tailored intervention will use participants' baseline survey responses to generate tailored educational messages about the HPV vaccine. These educational messages will reflect the top concerns indicated by the participant about the HPV vaccine. Additional tailoring will occur in the form of images matched to self-reported race and age, and using participants' first name in the information presented.
Untailored Intervention
n=372 Participants
Intervention: untailored educational materials. In this arm, patients will view educational information on the iPad that is not responsive to their baseline questionnaire answers. Untailored educational materials: The untailored intervention will present educational information on the iPad that is not responsive to participants' baseline questionnaire answers and instead is derived directly from the HPV "Vaccine Information Sheet" that has been created by the Centers for Disease Control and Prevention.
Usual Care
n=87 Participants
Intervention: usual care as experienced during appointment with primary care provider. Participants in the usual care arm will not view any educational materials or complete the baseline survey. Usual care: Those in the usual care arm will be provided with a paper version of the Post Intervention Survey. This will be provided to participants after their clinic visit is completed.
Percent of Participants Who Agreed They Felt Clear About Which Risks and Benefits of the HPV Vaccine Mattered Most to Them at Post-intervention
85 Percent of participants
87 Percent of participants
71 Percent of participants

PRIMARY outcome

Timeframe: 1 day

Outcome measures

Outcome measures
Measure
Tailored Intervention
n=380 Participants
Intervention: tailored educational materials. In this arm, participants will complete a baseline survey on an iPad, view a series of educational webpages on the iPad, and complete a brief post intervention survey. Tailored educational materials: The tailored intervention will use participants' baseline survey responses to generate tailored educational messages about the HPV vaccine. These educational messages will reflect the top concerns indicated by the participant about the HPV vaccine. Additional tailoring will occur in the form of images matched to self-reported race and age, and using participants' first name in the information presented.
Untailored Intervention
n=372 Participants
Intervention: untailored educational materials. In this arm, patients will view educational information on the iPad that is not responsive to their baseline questionnaire answers. Untailored educational materials: The untailored intervention will present educational information on the iPad that is not responsive to participants' baseline questionnaire answers and instead is derived directly from the HPV "Vaccine Information Sheet" that has been created by the Centers for Disease Control and Prevention.
Usual Care
n=87 Participants
Intervention: usual care as experienced during appointment with primary care provider. Participants in the usual care arm will not view any educational materials or complete the baseline survey. Usual care: Those in the usual care arm will be provided with a paper version of the Post Intervention Survey. This will be provided to participants after their clinic visit is completed.
Percent of Participants Who Agreed They Felt They Had Enough Support to Make a Decision About Getting the HPV Vaccine at Post-intervention
86 Percent of participants
87 Percent of participants
86 Percent of participants

PRIMARY outcome

Timeframe: 2 Months

Outcome measures

Outcome measures
Measure
Tailored Intervention
n=149 Participants
Intervention: tailored educational materials. In this arm, participants will complete a baseline survey on an iPad, view a series of educational webpages on the iPad, and complete a brief post intervention survey. Tailored educational materials: The tailored intervention will use participants' baseline survey responses to generate tailored educational messages about the HPV vaccine. These educational messages will reflect the top concerns indicated by the participant about the HPV vaccine. Additional tailoring will occur in the form of images matched to self-reported race and age, and using participants' first name in the information presented.
Untailored Intervention
n=155 Participants
Intervention: untailored educational materials. In this arm, patients will view educational information on the iPad that is not responsive to their baseline questionnaire answers. Untailored educational materials: The untailored intervention will present educational information on the iPad that is not responsive to participants' baseline questionnaire answers and instead is derived directly from the HPV "Vaccine Information Sheet" that has been created by the Centers for Disease Control and Prevention.
Usual Care
n=176 Participants
Intervention: usual care as experienced during appointment with primary care provider. Participants in the usual care arm will not view any educational materials or complete the baseline survey. Usual care: Those in the usual care arm will be provided with a paper version of the Post Intervention Survey. This will be provided to participants after their clinic visit is completed.
Percent of Participants Who Agreed They Felt Sure About the Best Choice Regarding the HPV Vaccine at Follow-up
96 percent of participants
95 percent of participants
94 percent of participants

PRIMARY outcome

Timeframe: 2 Months

Outcome measures

Outcome measures
Measure
Tailored Intervention
n=149 Participants
Intervention: tailored educational materials. In this arm, participants will complete a baseline survey on an iPad, view a series of educational webpages on the iPad, and complete a brief post intervention survey. Tailored educational materials: The tailored intervention will use participants' baseline survey responses to generate tailored educational messages about the HPV vaccine. These educational messages will reflect the top concerns indicated by the participant about the HPV vaccine. Additional tailoring will occur in the form of images matched to self-reported race and age, and using participants' first name in the information presented.
Untailored Intervention
n=153 Participants
Intervention: untailored educational materials. In this arm, patients will view educational information on the iPad that is not responsive to their baseline questionnaire answers. Untailored educational materials: The untailored intervention will present educational information on the iPad that is not responsive to participants' baseline questionnaire answers and instead is derived directly from the HPV "Vaccine Information Sheet" that has been created by the Centers for Disease Control and Prevention.
Usual Care
n=177 Participants
Intervention: usual care as experienced during appointment with primary care provider. Participants in the usual care arm will not view any educational materials or complete the baseline survey. Usual care: Those in the usual care arm will be provided with a paper version of the Post Intervention Survey. This will be provided to participants after their clinic visit is completed.
Percent of Participants Who Agreed They Knew Enough About the Risks and Benefits of the HPV Vaccine at Follow-up
76 Percent of participants
73 Percent of participants
60 Percent of participants

PRIMARY outcome

Timeframe: 2 Months

Outcome measures

Outcome measures
Measure
Tailored Intervention
n=148 Participants
Intervention: tailored educational materials. In this arm, participants will complete a baseline survey on an iPad, view a series of educational webpages on the iPad, and complete a brief post intervention survey. Tailored educational materials: The tailored intervention will use participants' baseline survey responses to generate tailored educational messages about the HPV vaccine. These educational messages will reflect the top concerns indicated by the participant about the HPV vaccine. Additional tailoring will occur in the form of images matched to self-reported race and age, and using participants' first name in the information presented.
Untailored Intervention
n=154 Participants
Intervention: untailored educational materials. In this arm, patients will view educational information on the iPad that is not responsive to their baseline questionnaire answers. Untailored educational materials: The untailored intervention will present educational information on the iPad that is not responsive to participants' baseline questionnaire answers and instead is derived directly from the HPV "Vaccine Information Sheet" that has been created by the Centers for Disease Control and Prevention.
Usual Care
n=178 Participants
Intervention: usual care as experienced during appointment with primary care provider. Participants in the usual care arm will not view any educational materials or complete the baseline survey. Usual care: Those in the usual care arm will be provided with a paper version of the Post Intervention Survey. This will be provided to participants after their clinic visit is completed.
Percent of Participants Who Agreed They Felt Clear About Which Risks and Benefits of the HPV Vaccine Mattered Most to Them at Follow-up
78 Percent of participants
78 Percent of participants
65 Percent of participants

PRIMARY outcome

Timeframe: 2 Months

Outcome measures

Outcome measures
Measure
Tailored Intervention
n=150 Participants
Intervention: tailored educational materials. In this arm, participants will complete a baseline survey on an iPad, view a series of educational webpages on the iPad, and complete a brief post intervention survey. Tailored educational materials: The tailored intervention will use participants' baseline survey responses to generate tailored educational messages about the HPV vaccine. These educational messages will reflect the top concerns indicated by the participant about the HPV vaccine. Additional tailoring will occur in the form of images matched to self-reported race and age, and using participants' first name in the information presented.
Untailored Intervention
n=155 Participants
Intervention: untailored educational materials. In this arm, patients will view educational information on the iPad that is not responsive to their baseline questionnaire answers. Untailored educational materials: The untailored intervention will present educational information on the iPad that is not responsive to participants' baseline questionnaire answers and instead is derived directly from the HPV "Vaccine Information Sheet" that has been created by the Centers for Disease Control and Prevention.
Usual Care
n=176 Participants
Intervention: usual care as experienced during appointment with primary care provider. Participants in the usual care arm will not view any educational materials or complete the baseline survey. Usual care: Those in the usual care arm will be provided with a paper version of the Post Intervention Survey. This will be provided to participants after their clinic visit is completed.
Percent of Participants Who Agreed They Felt They Had Enough Support to Make a Decision About Getting the HPV Vaccine at Follow-up
85 Percent of participants
84 Percent of participants
77 Percent of participants

Adverse Events

Tailored Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Untailored Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Usual Care

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Julie A Maertens

University of Colorado

Phone: 303-724-7319

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place