The Efficacy of Subconjunctival Bevacizumab in Diabetic Macular Edema

NCT ID: NCT02796183

Last Updated: 2016-06-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-01-31

Study Completion Date

2016-05-31

Brief Summary

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This study evaluates the effects of subconjunctivally injected bevacizumab in patients with diffuse diabetic macular edema.

Detailed Description

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At baseline, the macular thicknesses of both eyes of the patients with persistant diabetic macular edema were measured by optical coherence tomography. After 3.75mg bevacizumab was injected into subconjunctival space of the eyes with diabetic macular edema. The measurements of the macular thicknesses were repeated by optical coherence tomography in 15th, 30th, 60th day after injections. The macular thickness measurements before and after injection were compared.

Conditions

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Diabetic Macular Edema

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Diabetic macular edema

Bevacizumab (Altuzan) was injected subconjunctival space of the patients.

Group Type OTHER

Subconjunctival bevacizumab (Altuzan)

Intervention Type DRUG

Subconjunctival injections of Altuzan 3.75mg were applied in order to eliminate the macular edema.

Interventions

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Subconjunctival bevacizumab (Altuzan)

Subconjunctival injections of Altuzan 3.75mg were applied in order to eliminate the macular edema.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Having diffuse diabetic macular edema persisted at least 1 month
* No intravitreal injection in last 3 months.
* No retinal laser photocoagulation in last 6 months
* Not have any other macular disease causing macular edema

Exclusion Criteria

* Having ischemic macula
* Intravitreal injection in last 3 months.
* Retinal laser photocoagulation in last 6 months
* Have any other macular disease causing macular edema
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ondokuz Mayıs University

OTHER

Sponsor Role collaborator

Neon Hospital

OTHER

Sponsor Role lead

Responsible Party

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Volkan YETER

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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2015-1

Identifier Type: -

Identifier Source: org_study_id

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