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Intraoperative Sedatives and Postoperative Pain

NCT ID: NCT02784626

Last Updated: 2016-10-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-05-31

Study Completion Date

2016-09-30

Brief Summary

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In this study, based on the hypothesis that dexmedetomidine administered intraoperatively for sedation can reduce postoperative pain than that of propofol, the investigators examined the ability of dexmedetomidine to reduce postoperative pain in in patients undergoing the total knee arthroplasty.

Detailed Description

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Conditions

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Arthritis, Degenerative

Keywords

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Dexmedetomidine Propofol Pain, Postoperative

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Dexmedetomidine

Patients who received dexmedetomidine during the operation

Group Type EXPERIMENTAL

Dexmedetomidine

Intervention Type DRUG

Intraoperative sedation using dexmedetomidine

Propofol

Patients who received propofol during the operation

Group Type EXPERIMENTAL

Propofol

Intervention Type DRUG

Intraoperative sedation using propofol

Interventions

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Dexmedetomidine

Intraoperative sedation using dexmedetomidine

Intervention Type DRUG

Propofol

Intraoperative sedation using propofol

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing total knee arthroplasty
* Age: 20 - 80 yrs

Exclusion Criteria

* ASA classification ≥ 3
* Patient who do not want sedation during the surgery
* Patient who wants general anesthesia
* Cardiovascular disease
* Liver dysfunction
* Renal dysfunction
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Bundang Hospital

OTHER

Sponsor Role lead

Responsible Party

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Hyo-Seok Na

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Seoul National University Bundang Hospital

Seongnam-si, Gyeonggi-do, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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B-1603/339-005

Identifier Type: -

Identifier Source: org_study_id