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Translational Investigation of Growth and Everyday Routines in Kids

NCT ID: NCT02784509

Last Updated: 2024-12-24

Study Results

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

342 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-06-30

Study Completion Date

2020-09-30

Brief Summary

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The purpose of this study is to determine the effect of severe obesity on physical activity, sedentary behavior and cardiometabolic risk factors during childhood and adolescence and whether these associations are modified by race. Additionally, the study will investigate the contributions of (total, regional, and depot-specific) fat accumulation on changes in physical activity, sedentary behavior, and cardiometabolic risk factors during childhood and adolescence.

Detailed Description

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The proposed study will establish a prospective pediatric cohort to identify intervention targets based on the location, timing, barriers, and facilitators of current physical activity and sedentary behavior in a child's day. The project will be a prospective examination of 340 African American and White girls and boys aged 10 to 16 years, including 50% who are classified as severely obese. State-of-the-art technology will be used including accelerometry to quantify physical activity, magnetic resonance imaging to quantify fat accumulation, and geographic position system and ecological momentary assessment to identify environmental and socio-emotional barriers and facilitators. In further detail, this study will examine the following objectives:

Objective 1: Determine the effect of severe obesity on physical activity, sedentary behavior, and cardiometabolic risk factors during childhood and adolescence and whether these associations are modified by race.

Objective 2: Investigate the contribution of (total, regional, and depot-specific) fat accumulation on changes in physical activity, sedentary behavior, and cardiometabolic risk factors during childhood and adolescence.

Objective 3: Determine barriers and facilitators of physical activity that are related to obesity, including environmental and socio-emotional factors.

Conditions

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Childhood Obesity

Keywords

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Physical Activity Sedentary Behavior Cardiometabolic Risk Factors Childhood and Adolescence

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age 10-16 years
* Body weight \< 500 lbs.
* Ability to understand instructions and complete all study procedures

Exclusion Criteria

* Pregnant
* On a restrictive diet due to illness
* Significant physical or mental disabilities that impede walking, wearing accelerometer or GPS, or responding to EMA.
Minimum Eligible Age

10 Years

Maximum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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USDA Beltsville Human Nutrition Research Center

FED

Sponsor Role collaborator

Pennington Biomedical Research Center

OTHER

Sponsor Role lead

Responsible Party

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Amanda Staiano

PBRC Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Amanda E Staiano, PhD

Role: PRINCIPAL_INVESTIGATOR

PBRC Assistant Professor

Locations

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Pennington Biomedical Research Center

Baton Rouge, Louisiana, United States

Site Status

Countries

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United States

References

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Kracht CL, Beyl RA, Maher JP, Katzmarzyk PT, Staiano AE. Adolescents' sedentary time, affect, and contextual factors: An ecological momentary assessment study. Int J Behav Nutr Phys Act. 2021 Apr 15;18(1):53. doi: 10.1186/s12966-021-01121-y.

Reference Type BACKGROUND
PMID: 33858416 (View on PubMed)

Kepper MM, Staiano AE, Katzmarzyk PT, Reis RS, Eyler AA, Griffith DM, Kendall ML, ElBanna B, Denstel KD, Broyles ST. Using mixed methods to understand women's parenting practices related to their child's outdoor play and physical activity among families living in diverse neighborhood environments. Health Place. 2020 Mar;62:102292. doi: 10.1016/j.healthplace.2020.102292. Epub 2020 Feb 5.

Reference Type BACKGROUND
PMID: 32479369 (View on PubMed)

Kracht CL, Katzmarzyk PT, Staiano AE. Comparison of abdominal visceral adipose tissue measurements in adolescents between magnetic resonance imaging and dual-energy X-ray absorptiometry. Int J Obes (Lond). 2021 Jan;45(1):104-108. doi: 10.1038/s41366-020-0621-8. Epub 2020 Jun 4.

Reference Type BACKGROUND
PMID: 32499526 (View on PubMed)

Kracht CL, Champagne CM, Hsia DS, Martin CK, Newton RL Jr, Katzmarzyk PT, Staiano AE. Association Between Meeting Physical Activity, Sleep, and Dietary Guidelines and Cardiometabolic Risk Factors and Adiposity in Adolescents. J Adolesc Health. 2020 Jun;66(6):733-739. doi: 10.1016/j.jadohealth.2019.12.011. Epub 2020 Jan 25.

Reference Type BACKGROUND
PMID: 31987725 (View on PubMed)

Kepper MM, Staiano AE, Katzmarzyk PT, Reis RS, Eyler AA, Griffith DM, Kendall ML, ElBanna B, Denstel KD, Broyles ST. Neighborhood Influences on Women's Parenting Practices for Adolescents' Outdoor Play: A Qualitative Study. Int J Environ Res Public Health. 2019 Oct 12;16(20):3853. doi: 10.3390/ijerph16203853.

Reference Type BACKGROUND
PMID: 31614711 (View on PubMed)

Kracht CL, Chaput JP, Martin CK, Champagne CM, Katzmarzyk PT, Staiano AE. Associations of Sleep with Food Cravings, Diet, and Obesity in Adolescence. Nutrients. 2019 Nov 30;11(12):2899. doi: 10.3390/nu11122899.

Reference Type BACKGROUND
PMID: 31801259 (View on PubMed)

Kracht CL, Katzmarzyk PT, Champagne CM, Broyles ST, Hsia DS, Newton RL Jr, Staiano AE. Association between Sleep, Sedentary Time, Physical Activity, and Adiposity in Adolescents: A Prospective Observational Study. Med Sci Sports Exerc. 2023 Jan 1;55(1):110-118. doi: 10.1249/MSS.0000000000003018. Epub 2022 Aug 12.

Reference Type BACKGROUND
PMID: 35977103 (View on PubMed)

Staiano AE, Katzmarzyk PT. Visceral, subcutaneous, and total fat mass accumulation in a prospective cohort of adolescents. Am J Clin Nutr. 2022 Sep 2;116(3):780-785. doi: 10.1093/ajcn/nqac129.

Reference Type BACKGROUND
PMID: 35544287 (View on PubMed)

Fowler LA, Kracht CL, Denstel KD, Stewart TM, Staiano AE. Bullying experiences, body esteem, body dissatisfaction, and the moderating role of weight status among adolescents. J Adolesc. 2021 Aug;91:59-70. doi: 10.1016/j.adolescence.2021.07.006. Epub 2021 Jul 29.

Reference Type BACKGROUND
PMID: 34333320 (View on PubMed)

Hu K, Button AM, Tate CM, Kracht CL, Champagne CM, Staiano AE. Adolescent Diet Quality, Cardiometabolic Risk, and Adiposity: A Prospective Cohort. J Nutr Educ Behav. 2023 Dec;55(12):851-860. doi: 10.1016/j.jneb.2023.10.003. Epub 2023 Oct 27.

Reference Type BACKGROUND
PMID: 37897452 (View on PubMed)

Chen S, Kracht CL, Beyl RA, Staiano AE. Temporal Changes in Energy-Balance Behaviors and Home Factors in Adolescents with Normal Weight and Those with Overweight or Obesity. Int J Phys Act Health. 2023;2(2):5. doi: 10.18122/ijpah.020205.boisestate.

Reference Type BACKGROUND
PMID: 37675056 (View on PubMed)

Denstel KD, Beyl RA, Danos DM, Kepper MM, Staiano AE, Theall KT, Tseng TS, Broyles ST. An examination of the relationships between the neighborhood social environment, adiposity, and cardiometabolic disease risk in adolescence: a cross-sectional study. BMC Public Health. 2023 Sep 1;23(1):1692. doi: 10.1186/s12889-023-16580-0.

Reference Type BACKGROUND
PMID: 37658323 (View on PubMed)

Kracht CL, Pochana SS, Staiano AE. Associations Between Moderate to Vigorous Physical Activity, Sedentary Behavior, and Depressive Symptomatology in Adolescents: A Prospective Observational Cohort Study. J Phys Act Health. 2023 Feb 1;20(3):250-257. doi: 10.1123/jpah.2022-0345. Print 2023 Mar 1.

Reference Type BACKGROUND
PMID: 36724791 (View on PubMed)

Kracht CL, Wilburn JG, Broyles ST, Katzmarzyk PT, Staiano AE. Association of Night-Time Screen-Viewing with Adolescents' Diet, Sleep, Weight Status, and Adiposity. Int J Environ Res Public Health. 2022 Jan 15;19(2):954. doi: 10.3390/ijerph19020954.

Reference Type BACKGROUND
PMID: 35055781 (View on PubMed)

Kepper MM, Staiano AE, Broyles ST. The Potential for Bias across GPS-Accelerometer Combined Wear Criteria among Adolescents. Int J Environ Res Public Health. 2022 May 13;19(10):5931. doi: 10.3390/ijerph19105931.

Reference Type DERIVED
PMID: 35627467 (View on PubMed)

Fearnbach SN, Johannsen NM, Martin CK, Katzmarzyk PT, Beyl RA, Hsia DS, Carmichael OT, Staiano AE. A Pilot Study of Cardiorespiratory Fitness, Adiposity, and Cardiometabolic Health in Youth With Overweight and Obesity. Pediatr Exerc Sci. 2020 Apr 25;32(3):124-131. doi: 10.1123/pes.2019-0192.

Reference Type DERIVED
PMID: 32335525 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Related Links

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https://scholarworks.boisestate.edu/cgi/viewcontent.cgi?article=1083&context=ijpah

Temporal Changes in Energy-Balance Behaviors and Home Factors in Adolescents with Normal Weight and Those with Overweight or Obesity

https://labs.pbrc.edu/pediatric-obesity/documents/120.pdf

Associations Between Moderate to Vigorous Physical Activity, Sedentary Behavior, and Depressive Symptomatology in Adolescents: A Prospective Observational Cohort Study

https://labs.pbrc.edu/pediatric-obesity/documents/ijerph-19-059311.pdf

The Potential for Bias across GPS-Accelerometer Combined Wear Criteria among Adolescents

Other Identifiers

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3092-51000-04A

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

PBRC 2016-028

Identifier Type: -

Identifier Source: org_study_id