Potential Lead Exposure Through Eating Self-harvested Wild Game
NCT ID: NCT02775890
Last Updated: 2017-09-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
68 participants
OBSERVATIONAL
2019-02-01
2021-04-01
Brief Summary
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This study aims to assess if hunters eating meat shot with lead projectiles experience elevated lead levels. Hunters will be asked to provide blood samples 2-4 days after they eat meat harvested with lead bullets and provide a subsequent sample when they have abstained from eating wild game harvested with lead bullets. We have chosen to use deer as the species for this study to reduce variation and New Zealand is the ideal place to conduct this study because of year-round hunting of deer. This design will allows paired testing of subject lead levels.
Detailed Description
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Conditions
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Study Design
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CASE_CROSSOVER
PROSPECTIVE
Study Groups
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Eating lead-shot wild game
Hunters that have eaten lead-shot in the past week will have blood lead levels measured.
Eating wild game shot with lead bullets
Participants will eat meat harvested with lead bullets, prepare mince meat and eat at least a standard serving (\>85 grams).
Not eating lead-shot wild game
Hunters that have not eaten lead-shot in the past week will have blood lead levels measured.
No interventions assigned to this group
Interventions
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Eating wild game shot with lead bullets
Participants will eat meat harvested with lead bullets, prepare mince meat and eat at least a standard serving (\>85 grams).
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Any type of kidney dysfunction
* Individuals working in the following industries that may entail lead exposure:
1. lead-acid battery manufacture
2. lead smelting
3. non-ferrous smelting and casting (e.g. brass)
4. steel scrap smelting
5. scrap lead metal handling
6. cutting/welding steel scrap
7. machining or polishing lead-containing alloys
8. plastic production (where lead compounds are used as stabilisers)
9. demolition
10. lead soldering
11. plastic recycling
12. panel beating
13. paint removal
14. sandblasting
15. leadlight window manufacture
16. lead casting, e.g. fishing weights, toy soldiers
17. radiator repair,
18. car exhaust repair and engine reconditioning (for older makes and models of vehicles)
19. jewellery (silver) production
20. shooting range
18 Years
ALL
Yes
Sponsors
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Mayo Clinic
OTHER
Nelson Marlborough Institute of Technology
OTHER
Responsible Party
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Principal Investigators
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Eric J Buenz, PhD
Role: PRINCIPAL_INVESTIGATOR
Nelson Marlborough Institute of Technology
Central Contacts
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References
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Buenz EJ. Lead Exposure Through Eating Wild Game. Am J Med. 2016 May;129(5):457-8. doi: 10.1016/j.amjmed.2015.12.022. Epub 2016 Jan 18. No abstract available.
Buenz EJ. Eliminating potential lead exposure in imported New Zealand wild game. Public Health. 2016 Oct;139:236-237. doi: 10.1016/j.puhe.2016.06.025. Epub 2016 Jul 22. No abstract available.
Buenz EJ, Parry GJ, Peacey M. Consumption of wild-harvested meat from New Zealand feral animals provides a unique opportunity to study the health effects of lead exposure in hunters. Ambio. 2016 Sep;45(5):629-31. doi: 10.1007/s13280-016-0798-1. Epub 2016 Jun 25. No abstract available.
Buenz EJ. Non-lead ammunition may reduce lead levels in wild game. Environ Sci Pollut Res Int. 2016 Aug;23(15):15773. doi: 10.1007/s11356-016-7020-7. Epub 2016 Jun 8. No abstract available.
Buenz EJ, Parry GJ, Bauer BA, Matheny LM, Breukel K. A prospective observational study assessing the feasibility of measuring blood lead levels in New Zealand hunters eating meat harvested with lead projectiles. Contemp Clin Trials Commun. 2017 Feb 8;5:137-143. doi: 10.1016/j.conctc.2017.02.002. eCollection 2017 Mar.
Other Identifiers
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1NMIT2016
Identifier Type: -
Identifier Source: org_study_id