Comparison of Gas Consumption From Two Different Anesthesia Machines
NCT ID: NCT02774031
Last Updated: 2017-11-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
147 participants
INTERVENTIONAL
2016-05-31
2017-10-20
Brief Summary
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Since these machines were introduced, only a few studies have reported their functionality and effect on gas consumption. 20 to 55% reduction of gas consumption was found. The potential reduction may have been underestimated because in the majority of cases a FGF higher than 1 l/min was still used.
In this study the consumption of anesthetic gas (desflurane) delivered by two different anesthesia machines (Aisys and Flow-i) will be compared, with and without gas control delivery systems. Gas consumption and the time needed to reach the target level of anesthetic gas concentration will be assessed. Data needed will be collected directly from the anesthesia machine, PICIS ( Electronic anesthesia record) and EPJ (Electronic patient journal). The results of this study are of interest for intraoperative ventilation and of economic and ecological interest
.
Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Aisys with Et control
the ventilation modus will be pressure control ventilation with volume guarantee (PCV-VG). Settings: tidal volume (TV) 7-9 ml/kg BW, respiratory rate (RR) 12 -14/min, and 8-10 cmH2O positive end expiratory pressure (PEEP). Target for end expired desflurane concentration (F A des) is set to 4.2%, and target for end expired oxygen (F AO2) is set to 35%.
Aisys with Et control
Aisys conventional ventilation
50% oxygen and 50% air in 1 liter FGF will be administered. To be started with a FGF of 5l/min and vaporizer setting at 6 Vol% for 5 min. Then the FGF will be reduced to 1 l/min. 25 min later the vaporizer setting will be reduced to 5.5 Vol % for the rest of the study period. Ventilation modus for this group will be the same as for 'Aisys with PCV-VG'
Aisys conventional
Flow-i with ACG
the following parameters will be preset: FIO2= 40%; end expired gas concentration (FA des) to 4.2%; speed 6; and ventilation modus = pressure regulated volume control (PRVC) with tidal volume (TV) 7-9 ml/kg BW, respiratory rate (RR)12-14/min, and 8-10 cmH2O positive end expiratory pressure (PEEP).
Flow-i with ACG
Flow-I conventional ventilation
50% oxygen and 50% air in 1 liter FGF will be administered. To be started with a FGF of 5l/min and vaporizer setting at 6 Vol% for 5 min. Then the FGF will be reduced to 1 l/min. 25 min later the vaporizer setting will be reduced to 5.5 Vol % for the rest of the study period. Ventilation modus for this group will be the same as for 'Flow-i with ACG'
Flow-i conventional
Interventions
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Aisys with Et control
Aisys conventional
Flow-i with ACG
Flow-i conventional
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Pregnancy
* American Society of Anesthesiologists physical status classification system (ASA) IV-VI
Patients who are included in the study can be excluded for the following reasons:
* surgical technical problems (for example surgically impossible to complete the operation with robot assisted surgery)
* technical problems with the anesthesia machine
18 Years
ALL
No
Sponsors
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Norwegian University of Science and Technology
OTHER
St. Olavs Hospital
OTHER
Responsible Party
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Principal Investigators
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Pål Klepstad, PhD MD
Role: STUDY_DIRECTOR
St. Olavs Hospital
Locations
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Department of Anesthesia, St.Olavs University Hospital
Trondheim, , Norway
Countries
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Other Identifiers
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2015/2132
Identifier Type: -
Identifier Source: org_study_id