Post Authorisation Safety Study With Raxone in LHON Patients

NCT ID: NCT02771379

Last Updated: 2021-07-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

229 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-09-30

Study Completion Date

2021-04-16

Brief Summary

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This study is a multicentre, prospective, non-interventional post-authorisation safety study (PASS) of the clinical outcomes for patients with LHON treated with Raxone®.

No medication will be provided as part of this study. Raxone® will be obtained through commercial channels.

Detailed Description

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Conditions

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Leber's Hereditary Optic Neuropathy (LHON)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients who are treated with Raxone®

Idebenone

Intervention Type DRUG

Raxone 900mg/day as per Raxone SmPC and medical judgement of treating physician.

Interventions

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Idebenone

Raxone 900mg/day as per Raxone SmPC and medical judgement of treating physician.

Intervention Type DRUG

Other Intervention Names

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Raxone®

Eligibility Criteria

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Inclusion Criteria

* Patient prescribed Raxone® for the treatment of LHON;
* Patient has completed an Informed Consent Form (ICF) indicating that he/she (or a legally acceptable representative) has been informed of all pertinent aspects of the study and has agreed to participate in the study;
* Patient is not participating in any interventional study.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Santhera Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Universitaetsklinikum Graz

Graz, , Austria

Site Status

Medical University of Vienna

Vienna, , Austria

Site Status

CHU de Nîmes - Hôpital Carémeau

Nîmes, Gard, France

Site Status

CHU Angers - Hôpital Hôtel Dieu

Angers, Maine Et Loire, France

Site Status

Hopital Roger Salengro - CHU Lille

Lille, Nord, France

Site Status

Hôpital Européen Georges Pompidou

Paris, Paris Cedex 15, France

Site Status

CHU Amiens - Centre Saint Victor

Amiens, Somme, France

Site Status

Hospices Civils de Lyon

Lyon, , France

Site Status

Hopital Neurologique Pierre Wertheimer

Lyon, , France

Site Status

Centre Hospitalier National d'Ophtalmologie (CHNO) des Quinze-Vingts

Paris, , France

Site Status

Fondation Ophtalmologique Adolphe de Rothschild

Paris, , France

Site Status

Julius Maximilians University

Würzburg, Bavaria, Germany

Site Status

Universitaetsklinikum Essen

Essen, , Germany

Site Status

Universitaetsklinikum Freiburg

Freiburg im Breisgau, , Germany

Site Status

Universitaetsklinikum Hamburg-Eppendorf

Hamburg, , Germany

Site Status

Universitaetsklinikum Heidelberg

Heidelberg, , Germany

Site Status

Friedrich-Baur-Institut

Munich, , Germany

Site Status

Universitaetsklinikum Muenster

Münster, , Germany

Site Status

Dietrich-Bonhoeffer-Klinikum Neubrandenburg

Neubrandenburg, , Germany

Site Status

Universitaetsklinikum Regensburg

Regensburg, , Germany

Site Status

Athens Ophthalmological Center

Athens, , Greece

Site Status

Università di Bologna-Clinica Neurologica-Dipartimento di Scienze Neurologiche

Bologna, , Italy

Site Status

Ospedale San Raffaele

Milan, , Italy

Site Status

Azienda Ospedaliera S. Camillo Forlanini

Rome, , Italy

Site Status

Universitair Medisch Centrum Groningen

Groningen, , Netherlands

Site Status

Maastricht University Medical Center

Maastricht, , Netherlands

Site Status

Countries

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Austria France Germany Greece Italy Netherlands

Other Identifiers

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SNT-IV-003

Identifier Type: -

Identifier Source: org_study_id

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