Trial Outcomes & Findings for The Impacts of Pulmonary Rehabilitation Therapy on Patients After Thoracic Surgery (NCT NCT02757092)
NCT ID: NCT02757092
Last Updated: 2020-11-03
Results Overview
Exercise capacity as assessed by 6 min walking test(M).The 6-min walk test (6 MWT) is a submaximal exercise test that entails measurement of distance walked over a span of 6 minutes. The 6-minute walk distance (6 MWD) provides a measure for integrated global response of multiple cardiopulmonary and musculoskeletal systems involved in exercise . The 6 MWT provides information regarding functional capacity, response to therapy and prognosis across a broad range of chronic cardiopulmonary conditions .The normal range in aged patients 60-69 y(male 572 m,female 538 M),70-79 y(male 527 m,female 471 M),80-89 y(male 417 m,female 392 M)higher scores mean a better outcome.
COMPLETED
NA
36 participants
assessed at discharge 2weeks
2020-11-03
Participant Flow
The study was design a Prospective randomized control trial,and enrolled a total of 36 older patients with lung tumors after thoracoscopic surgery in the cardiothoracic and vascular ordinary ward between March 31 2016 to April 1 2017. The study was performed conducted in Kaohsiung Chang Gung Memorial Hospital, Taiwan
Participant milestones
| Measure |
Home Pulmonary Rehabilitation Group
Pulmonary Rehabilitation group accept the pulmonary rehabilitation( breathing exercise, extremities exercise, breathing muscle training, incentive spirometry (Triflo-II) training, intermittent positive pressure ventilation, chest physical therapy ) in operation stage on before op-day 3 day and after op-day 2 weeks and keep home based pulmonary rehabilitation on discharge 2 weeks, 6 weeks and after 12 weeks.
study group : received pain medication and standard care
|
Study Group
study group accept the pulmonary rehabilitation( breathing exercise, extremities exercise, breathing muscle training, incentive spirometry (Triflo-II) training, intermittent positive pressure ventilation, chest physical therapy ) in operation stage on before op-day 3 day and after op-day ,after discharged received standard care
|
|---|---|---|
|
Overall Study
STARTED
|
18
|
18
|
|
Overall Study
COMPLETED
|
18
|
18
|
|
Overall Study
NOT COMPLETED
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Race and Ethnicity were not collected from any participant.
Baseline characteristics by cohort
| Measure |
Pulmonary Rehabilitation Group
n=18 Participants
arm group accept the pulmonary rehabilitation( smoking cession before operation, breathing exercise, extremities exercise, breathing muscle training, incentive spirometry (Triflo-II) training, intermittent positive pressure ventilation, chest physical therapy and pain control) in operation stage on before op-day 3 day and after op-day 2 weeks and keep home based pulmonary rehabilitation on discharge 2 weeks, 6 weeks and after 12 weeks.
|
The Control Group
n=18 Participants
The control group received pain medication and usual care.
|
Total
n=36 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Categorical
Count of Participants · <=18 years
|
0 Participants
n=18 Participants
|
0 Participants
n=18 Participants
|
0 Participants
n=36 Participants
|
|
Age, Categorical
Count of Participants · Between 18 and 65 years
|
0 Participants
n=18 Participants
|
0 Participants
n=18 Participants
|
0 Participants
n=36 Participants
|
|
Age, Categorical
Count of Participants · >=65 years
|
18 Participants
n=18 Participants
|
18 Participants
n=18 Participants
|
36 Participants
n=36 Participants
|
|
Sex: Female, Male
Female
|
8 Participants
n=18 Participants
|
11 Participants
n=18 Participants
|
19 Participants
n=36 Participants
|
|
Sex: Female, Male
Male
|
10 Participants
n=18 Participants
|
7 Participants
n=18 Participants
|
17 Participants
n=36 Participants
|
|
Race and Ethnicity Not Collected
|
—
|
—
|
0 Participants
Race and Ethnicity were not collected from any participant.
|
|
Region of Enrollment
Taiwan
|
18 Participants
n=18 Participants
|
18 Participants
n=18 Participants
|
36 Participants
n=36 Participants
|
|
BMI (Kg/m2)
|
25.08 Kg/m2
STANDARD_DEVIATION 3.3 • n=18 Participants
|
23.46 Kg/m2
STANDARD_DEVIATION 2.8 • n=18 Participants
|
24.27 Kg/m2
STANDARD_DEVIATION 3.05 • n=36 Participants
|
|
BW (kg)
|
65.33 kg
STANDARD_DEVIATION 11.71 • n=18 Participants
|
57.98 kg
STANDARD_DEVIATION 9.44 • n=18 Participants
|
61.66 kg
STANDARD_DEVIATION 10.57 • n=36 Participants
|
|
Amount of comorbidities
Hypertension
|
7 Participants
n=18 Participants
|
11 Participants
n=18 Participants
|
18 Participants
n=36 Participants
|
|
Amount of comorbidities
DM
|
5 Participants
n=18 Participants
|
4 Participants
n=18 Participants
|
9 Participants
n=36 Participants
|
|
Amount of comorbidities
Cardiovascular diseases n
|
2 Participants
n=18 Participants
|
4 Participants
n=18 Participants
|
6 Participants
n=36 Participants
|
|
Amount of comorbidities
COPD
|
9 Participants
n=18 Participants
|
2 Participants
n=18 Participants
|
11 Participants
n=36 Participants
|
|
smoking
|
6 Participants
n=18 Participants
|
4 Participants
n=18 Participants
|
10 Participants
n=36 Participants
|
|
total hospital days
|
8.68 days
STANDARD_DEVIATION 4.41 • n=18 Participants
|
8.32 days
STANDARD_DEVIATION 3.28 • n=18 Participants
|
8.5 days
STANDARD_DEVIATION 3.85 • n=36 Participants
|
|
PFT
FEV1(liter/sec)
|
1.88 liter/sec
STANDARD_DEVIATION 0.44 • n=18 Participants
|
1.78 liter/sec
STANDARD_DEVIATION 0.93 • n=18 Participants
|
1.83 liter/sec
STANDARD_DEVIATION 0.69 • n=36 Participants
|
|
PFT
FVC(liter/sec)
|
1.48 liter/sec
STANDARD_DEVIATION 0.47 • n=18 Participants
|
1.43 liter/sec
STANDARD_DEVIATION 0.71 • n=18 Participants
|
1.45 liter/sec
STANDARD_DEVIATION 0.59 • n=36 Participants
|
|
PFT
MMEF25-75(liter/sec)
|
1.80 liter/sec
STANDARD_DEVIATION 1.17 • n=18 Participants
|
1.41 liter/sec
STANDARD_DEVIATION 0.77 • n=18 Participants
|
1.61 liter/sec
STANDARD_DEVIATION 0.97 • n=36 Participants
|
|
PFT
PEFR(liter/sec)
|
4.08 liter/sec
STANDARD_DEVIATION 2.05 • n=18 Participants
|
3.01 liter/sec
STANDARD_DEVIATION 1.46 • n=18 Participants
|
3.55 liter/sec
STANDARD_DEVIATION 1.76 • n=36 Participants
|
|
FEV1/FVC(%)
|
79.02 %
STANDARD_DEVIATION 17.01 • n=18 Participants
|
81.03 %
STANDARD_DEVIATION 10.45 • n=18 Participants
|
80.03 %
STANDARD_DEVIATION 13.73 • n=36 Participants
|
|
Modified Borg score
|
1.61 scores on a scale
STANDARD_DEVIATION 0.6 • n=18 Participants
|
1.89 scores on a scale
STANDARD_DEVIATION 0.58 • n=18 Participants
|
1.75 scores on a scale
STANDARD_DEVIATION 0.59 • n=36 Participants
|
|
MIP(cmH2O)
|
50.22 cmH2O
STANDARD_DEVIATION 11.89 • n=18 Participants
|
49.73 cmH2O
STANDARD_DEVIATION 16.83 • n=18 Participants
|
49.98 cmH2O
STANDARD_DEVIATION 13.82 • n=36 Participants
|
|
MEP(cmH2O)
|
61.89 cmH20
STANDARD_DEVIATION 24.00 • n=18 Participants
|
50.40 cmH20
STANDARD_DEVIATION 21.06 • n=18 Participants
|
56.15 cmH20
STANDARD_DEVIATION 23.36 • n=36 Participants
|
|
Lung capacity (mL/sec)
|
1200.00 mL
STANDARD_DEVIATION 534.68 • n=18 Participants
|
1000.00 mL
STANDARD_DEVIATION 524.68 • n=18 Participants
|
1100.00 mL
STANDARD_DEVIATION 529.68 • n=36 Participants
|
|
6-min walk test(meter,M)
|
364.33 meter
STANDARD_DEVIATION 49.89 • n=18 Participants
|
315.22 meter
STANDARD_DEVIATION 59.34 • n=18 Participants
|
339.78 meter
STANDARD_DEVIATION 54.62 • n=36 Participants
|
|
Anesthesia time(min)
|
271.15 min
STANDARD_DEVIATION 83.52 • n=18 Participants
|
249.84 min
STANDARD_DEVIATION 70.83 • n=18 Participants
|
260.5 min
STANDARD_DEVIATION 77.18 • n=36 Participants
|
|
American Society of Anesthesiologists (ASA) score
|
2.11 scores on a scale
STANDARD_DEVIATION 0.32 • n=18 Participants
|
2.11 scores on a scale
STANDARD_DEVIATION 0.58 • n=18 Participants
|
2.11 scores on a scale
STANDARD_DEVIATION 0.45 • n=36 Participants
|
|
Surgery time(min)
|
236.90 min
STANDARD_DEVIATION 79.02 • n=18 Participants
|
225.26 min
STANDARD_DEVIATION 66.32 • n=18 Participants
|
231.08 min
STANDARD_DEVIATION 72.67 • n=36 Participants
|
|
chest tube placement time(hours)
|
115.05 hours
STANDARD_DEVIATION 37.56 • n=18 Participants
|
118.11 hours
STANDARD_DEVIATION 50.90 • n=18 Participants
|
116.58 hours
STANDARD_DEVIATION 44.23 • n=36 Participants
|
|
surgery method
lobectomy
|
11 Participants
n=18 Participants
|
12 Participants
n=18 Participants
|
23 Participants
n=36 Participants
|
|
surgery method
wedge resection
|
5 Participants
n=18 Participants
|
5 Participants
n=18 Participants
|
10 Participants
n=36 Participants
|
|
surgery method
sefmentectomy
|
2 Participants
n=18 Participants
|
1 Participants
n=18 Participants
|
3 Participants
n=36 Participants
|
|
wedge resection
|
5 Participants
n=18 Participants
|
5 Participants
n=18 Participants
|
10 Participants
n=36 Participants
|
|
surgery site
Right upper lobe
|
12 Participants
n=18 Participants
|
7 Participants
n=18 Participants
|
19 Participants
n=36 Participants
|
|
surgery site
Right middle lobe
|
1 Participants
n=18 Participants
|
1 Participants
n=18 Participants
|
2 Participants
n=36 Participants
|
|
surgery site
Right low lobe
|
3 Participants
n=18 Participants
|
4 Participants
n=18 Participants
|
7 Participants
n=36 Participants
|
|
surgery site
left upper lobe
|
0 Participants
n=18 Participants
|
5 Participants
n=18 Participants
|
5 Participants
n=36 Participants
|
|
surgery site
left low lobe
|
3 Participants
n=18 Participants
|
1 Participants
n=18 Participants
|
4 Participants
n=36 Participants
|
|
postoperative diagnosis
small cell carcinoma
|
1 Participants
n=18 Participants
|
0 Participants
n=18 Participants
|
1 Participants
n=36 Participants
|
|
postoperative diagnosis
adenocarcinoma
|
14 Participants
n=18 Participants
|
13 Participants
n=18 Participants
|
27 Participants
n=36 Participants
|
|
postoperative diagnosis
large cell carcinoma
|
1 Participants
n=18 Participants
|
0 Participants
n=18 Participants
|
1 Participants
n=36 Participants
|
|
postoperative diagnosis
sguamous cell carcinoma
|
0 Participants
n=18 Participants
|
3 Participants
n=18 Participants
|
3 Participants
n=36 Participants
|
|
postoperative diagnosis
benign lung tumor
|
2 Participants
n=18 Participants
|
2 Participants
n=18 Participants
|
4 Participants
n=36 Participants
|
|
postoperative stages of lung cancer
stage1 n(%)
|
11 Participants
n=18 Participants
|
8 Participants
n=18 Participants
|
19 Participants
n=36 Participants
|
|
postoperative stages of lung cancer
stage2 n(%)
|
4 Participants
n=18 Participants
|
7 Participants
n=18 Participants
|
11 Participants
n=36 Participants
|
|
postoperative stages of lung cancer
Benign lung tumor(%)
|
2 Participants
n=18 Participants
|
2 Participants
n=18 Participants
|
4 Participants
n=36 Participants
|
|
postoperative stages of lung cancer
others,ground-glass opacity(%)
|
1 Participants
n=18 Participants
|
1 Participants
n=18 Participants
|
2 Participants
n=36 Participants
|
|
postoperative complications
emphysema
|
16 Participants
n=18 Participants
|
15 Participants
n=18 Participants
|
31 Participants
n=36 Participants
|
|
postoperative complications
air leak
|
6 Participants
n=18 Participants
|
6 Participants
n=18 Participants
|
12 Participants
n=36 Participants
|
PRIMARY outcome
Timeframe: assessed at discharge 2weeksPopulation: 2-WAY repeated measures ANOVA method was used for exercise capacity.an intention-to-treat analysis was performed.group × time interactions were observed for the 6-min walking distance.
Exercise capacity as assessed by 6 min walking test(M).The 6-min walk test (6 MWT) is a submaximal exercise test that entails measurement of distance walked over a span of 6 minutes. The 6-minute walk distance (6 MWD) provides a measure for integrated global response of multiple cardiopulmonary and musculoskeletal systems involved in exercise . The 6 MWT provides information regarding functional capacity, response to therapy and prognosis across a broad range of chronic cardiopulmonary conditions .The normal range in aged patients 60-69 y(male 572 m,female 538 M),70-79 y(male 527 m,female 471 M),80-89 y(male 417 m,female 392 M)higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 2weeks Exercise Capacity
|
408.61 meter(M)
Standard Deviation 62.85
|
311.94 meter(M)
Standard Deviation 84.65
|
PRIMARY outcome
Timeframe: assessed at discharge.6weeksPopulation: 2-WAY repeated measures ANOVA method was used for exercise capacity. For group comparisons, an intention-to-treat analysis was performed.group × time interactions were observed for the 6-min walking distance.
Exercise capacity as assessed by 6 min walking test(M).The 6-min walk test (6 MWT) is a submaximal exercise test that entails measurement of distance walked over a span of 6 minutes. The 6-minute walk distance (6 MWD) provides a measure for integrated global response of multiple cardiopulmonary and musculoskeletal systems involved in exercise . The 6 MWT provides information regarding functional capacity, response to therapy and prognosis across a broad range of chronic cardiopulmonary conditions .The normal range in aged patients 60-69 y(male 572 m,female 538 M),70-79 y(male 527 m,female 471 M),80-89 y(male 417 m,female 392 M)higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 6 Weeks Exercise Capacity
|
411.63 meter(M)
Standard Deviation 44.49
|
332.94 meter(M)
Standard Deviation 54.03
|
PRIMARY outcome
Timeframe: assessed at discharge 12 weeksPopulation: 2-WAY repeated measures ANOVA method was used for exercise capacity. For group comparisons, an intention-to-treat analysis was performed. group × time interactions were observed for the 6-min walking distance.
Exercise capacity as assessed by 6 min walking test(M).The 6-min walk test (6 MWT) is a submaximal exercise test that entails measurement of distance walked over a span of 6 minutes. The 6-minute walk distance (6 MWD) provides a measure for integrated global response of multiple cardiopulmonary and musculoskeletal systems involved in exercise . The 6 MWT provides information regarding functional capacity, response to therapy and prognosis across a broad range of chronic cardiopulmonary conditions .The normal range in aged patients 60-69 y(male 572 m,female 538 M),70-79 y(male 527 m,female 471 M),80-89 y(male 417 m,female 392 M).higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 12 Weeks Exercise Capacity
|
397.06 meter(M)
Standard Deviation 50.37
|
345.17 meter(M)
Standard Deviation 46.04
|
SECONDARY outcome
Timeframe: assessments at 2 weeks after dischargePopulation: 2-WAY repeated measures ANOVA method was used for pulmonary function test.
Forced vital capacity (FVC in L/sec) assessment by pulmonary function test.Normal values in healthy males aged 20-60 from 4.5-3.5 L/sec,and for females from 3.25-2.5 L/sec ,and whether higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 2 Weeks Forced Vital Capacity (FVC in Liter(L)/Sec)
|
2.48 liter(L)/sec
Standard Deviation 0.80
|
2.00 liter(L)/sec
Standard Deviation 0.85
|
SECONDARY outcome
Timeframe: assessed at 2 weeks after dischargePopulation: 2-WAY repeated measures ANOVA method was used for pulmonary function test.
The Forced Expiratory Volume in 1 Second parameter measures the volume of air that was exhaled into the mouthpiece in the first second after a full inhalation. The Measured column represents the total volume exhaled during the first second, in liters. Normal values in healthy males aged 20-60 range from 4.5 to 3.5 liters, and normal values for females aged 20-60 range from 3.25 to 2.5 liters. The Predicted column compares the actual volume breathed out during the first second of your test to an average of the normal volume breathed out in 1 second for a person of the same gender, height, and age. This value is expressed as a percentage, with normal test values being between 80% and 120% of the average (predicted) values.and whether higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 2weeks Forced Expiratory Volume in 1 Second(FEV1,Liter(L)/Sec)
|
1.97 liter(L)/sec
Standard Deviation 0.54
|
1.57 liter(L)/sec
Standard Deviation 0.69
|
SECONDARY outcome
Timeframe: assessed at discharge 2weeksPopulation: 2-WAY repeated measures ANOVA method was used for pulmonary function test.
Forced expiratory flow (FEF) is the flow (or speed) of air coming out of the lung during the middle portion of a forced expiration. It can be given at discrete times, generally defined by what fraction of the forced vital capacity (FVC) has been exhaled. The usual discrete intervals are 25%, 50% and 75%, usually 25-75% (FEF25-75%).Predicted normal values for FEF depend on age, sex, height, mass and ethnicity as well as the research study that they are based on assessment by pulmonary function test and higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 2weeks MMEF 25-75%(Liter(L)/Sec)
|
2.00 liter(L)/sec
Standard Deviation 0.81
|
1.58 liter(L)/sec
Standard Deviation 0.94
|
SECONDARY outcome
Timeframe: assessed at discharge 2weeksPopulation: 2-WAY repeated measures ANOVA method was used for pulmonary function test.
Peak expiratory flow rate (PEFR in liter(L)/sec) assessment by pulmonary function test.It measures the airflow through the bronchi and thus the degree of obstruction in the airways. Peak expiratory flow is typically measured in units of liters per second (L/sec).when measured as part of spirometry.The normal range 500-700 L/sec In men, for women, the normal range is 380-500 L/sec.higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 2weeks Peak Expiratory Flow Rate(PEFR , Liter(L)/Sec)
|
5.68 liter(L)/sec
Standard Deviation 2.35
|
4.27 liter(L)/sec
Standard Deviation 2.35
|
SECONDARY outcome
Timeframe: assessed at discharge 2 weeks.Population: Two-way repeated measures ANOVA for MIP. For group comparisons, an intention-to-treat analysis was performed. group × time interactions were observed for the MIP
Inspiratory muscle strength as assessed by Maximum inspiratory pressure (MIP, cmH2O).The MIP is a measure of inspiratory muscle strength produced by a sub-atmospheric pressure The normal.range of MIP in elderly people approximately 60 cm H2O for men and 40 cm H2O for women .An absolute MIP value of \< - 40 cm H2O is always abnormal,and higher scores was mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 2weeks Inspiratory Muscle Strength(MIP,cmH2O)
|
90.00 cmH2O
Standard Deviation 25.66
|
67.33 cmH2O
Standard Deviation 28.15
|
SECONDARY outcome
Timeframe: assessed at discharge 2 weeksPopulation: Two-way repeated measures ANOVA for MEP. an intention-to-treat analysis was performed.group × time interactions were observed for the MEP
The Maximal Expiratory Pressure (MEP) are global measures of the maximal strength of the respiratory muscles.(MEP, cmH2O) .MEP is a supra-atmospheric pressure which can be developed in an effort of the abdominal and intercostal muscles.Expiratory muscle strength assesses extrathoracic muscle health.An absolute MEP value of \< 80 cmH2O is always abnormal, and higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 2weeks Expiratory Muscle Strength(MEP,cmH2O)
|
89.44 cmH2O
Standard Deviation 28.79
|
68.89 cmH2O
Standard Deviation 22.72
|
SECONDARY outcome
Timeframe: assessed at discharge 2 weeksPopulation: Two-way repeated measures ANOVA for Modified Borg score.an intention-to-treat analysis was performed.group × time interactions were observed for the Modified Borg score
Dyspnea score as assessed by Modified Borg score, The literature review clearly showed that the Modified Borg score was a valid and reliable tool when used in pulmonary medicine and in exercise physiology studies.The scale used was perceived exertion adapted to be appropriate for measuring dyspnea. This consisted of a vertical scale labelled 0-10, with corresponding verbal expressions of progressively increasing perceived sensation intensity. It starts at number 0 that mean breathing is no difficulty at all and progresses through to number 10 that mean breathing difficulty is maximal.so higher scores mean a worse outcome
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 2 Weeks Modified Borg Score
|
1.06 scores on a scale
Standard Deviation 0.54
|
1.72 scores on a scale
Standard Deviation 0.67
|
SECONDARY outcome
Timeframe: assessed at discharge 2 weeksPopulation: Two-way repeated measures ANOVA for Lung expansion capacity. an intention-to-treat analysis was performed.group × time interactions were observed for the Lung expansion capacity.
Lung expansion capacity as assessed by incentive spirometry with the flow-oriented device( Triflow II,volume × seconds) (ml).Incentive spirometry that feedback respiratory training can improve respiratory function, endurance for exercise capacity,Wide flow rate range from 600 - 1200(volume × seconds) (ml).higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 2weeks Lung Expansion Capacity
|
1450.00 (ml)
Standard Deviation 619.53
|
1033.33 (ml)
Standard Deviation 388.65
|
SECONDARY outcome
Timeframe: at 2weeks after dischargePopulation: Pearson chi-square test was used for Pulmonary complication on discharge 2 weeks .Data is presented as either n(%).
Pulmonary complication as assessed by Chest X-ray.pneumonia.lung collapse.atelectasis.emphysema and pleural effusion were collected.some patients have two pulmonary complications at the same time, such as emphysem and infiltration, so the total number is not necessarily equal to 18.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Postoperative 2 Weeks Pulmonary Complications
pneumonia
|
0 Participants
|
1 Participants
|
|
Postoperative 2 Weeks Pulmonary Complications
atelectasis
|
1 Participants
|
2 Participants
|
|
Postoperative 2 Weeks Pulmonary Complications
pleural effusion
|
0 Participants
|
1 Participants
|
|
Postoperative 2 Weeks Pulmonary Complications
emphysema
|
0 Participants
|
1 Participants
|
|
Postoperative 2 Weeks Pulmonary Complications
pulmonary infilation
|
1 Participants
|
0 Participants
|
SECONDARY outcome
Timeframe: assessments at discharge 6 weeksPopulation: 2-WAY repeated measures ANOVA method was used for pulmonary function test.
Forced vital capacity (FVC in (liter(L)/sec)) assessment by pulmonary function test.Normal values in healthy males aged 20-60 from 4.5-3.5 (liter(L)/sec),and for females from 3.25-2.5 (liter(L)/sec) ,and whether higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 6 Weeks Forced Vital Capacity(Liter(L)/Sec)
|
2.48 liter( L)/sec
Standard Deviation 0.88
|
1.97 liter( L)/sec
Standard Deviation 0.80
|
SECONDARY outcome
Timeframe: assessed at discharge 6weeksPopulation: 2-WAY repeated measures ANOVA method was used for pulmonary function test.
The Forced Expiratory Volume in 1 Second parameter measures the volume of air that was exhaled into the mouthpiece in the first second after a full inhalation. The Measured column represents the total volume exhaled during the first second, in liters. Normal values in healthy males aged 20-60 range from 4.5 to 3.5 liters, and normal values for females aged 20-60 range from 3.25 to 2.5 liters. The Predicted column compares the actual volume breathed out during the first second of your test to an average of the normal volume breathed out in 1 second for a person of the same gender, height, and age. This value is expressed as a percentage, with normal test values being between 80% and 120% of the average (predicted) values.and whether higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 6 Weeks Forced Expiratory Volume in 1 Second (FEV1,Liter(L)/Sec)
|
2.02 liter(L)/sec
Standard Deviation 0.60
|
1.58 liter(L)/sec
Standard Deviation 0.62
|
SECONDARY outcome
Timeframe: assessed at discharge 6 weeksPopulation: 2-WAY repeated measures ANOVA method was used for pulmonary function test.
Forced expiratory flow (FEF) is the flow (or speed) of air coming out of the lung during the middle portion of a forced expiration. It can be given at discrete times, generally defined by what fraction of the forced vital capacity (FVC) has been exhaled. The usual discrete intervals are 25%, 50% and 75%, usually 25-75% (FEF25-75%).Predicted normal values for FEF depend on age, sex, height, mass and ethnicity as well as the research study that they are based on assessment by pulmonary function test and higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 6weeks MMEF 25-75%(Liter(L)/Sec)
|
2.12 liter(L)/sec
Standard Deviation 0.74
|
2.08 liter(L)/sec
Standard Deviation 1.46
|
SECONDARY outcome
Timeframe: assessed at discharge .6weeksPopulation: 2-WAY repeated measures ANOVA method was used for pulmonary function test.
Peak expiratory flow rate (PEFR in liter(L)/sec) assessment by pulmonary function test.It measures the airflow through the bronchi and thus the degree of obstruction in the airways. Peak expiratory flow is typically measured in units of liters per second (L/sec).when measured as part of spirometry.The normal range 500-700 L/sec In men, for women, the normal range is 380-500 L/sec.higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 6weeks Peak Expiratory Flow Rate(PEFR in Liter( L)/Sec)
|
5.13 liter(L)/sec
Standard Deviation 1.50
|
4.71 liter(L)/sec
Standard Deviation 2.13
|
SECONDARY outcome
Timeframe: assessed at discharge6 weeks.Population: Two-way repeated measures ANOVA for MIP. an intention-to-treat analysis was performed.group × time interactions were observed for the MIP
Inspiratory muscle strength as assessed by Maximum inspiratory pressure (MIP, cmH2O).The MIP is a measure of inspiratory muscle strength produced by a sub-atmospheric pressure The normal.range of MIP in elderly people approximately 60 cm H2O for men and 40 cm H2O for women .An absolute MIP value of \< - 40 cm H2O is always abnormal,and higher scores was mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 6 Weeks Inspiratory Muscle Strength(MIP,cmH2O)
|
93.33 cmH2O
Standard Deviation 34.47
|
64.67 cmH2O
Standard Deviation 20.3
|
SECONDARY outcome
Timeframe: assessed at discharge 6 weeksPopulation: Two-way repeated measures ANOVA for MEP. an intention-to-treat analysis was performed.group × time interactions were observed for the MEP
The Maximal Expiratory Pressure (MEP,cmH2O) are global measures of the maximal strength of the respiratory muscles.(MEP, cmH2O) .MEP is a supra-atmospheric pressure which can be developed in an effort of the abdominal and intercostal muscles.Expiratory muscle strength assesses extrathoracic muscle health.An absolute MEP value of \< 80 cm H2O is always abnormal, and higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 6weeks Expiratory Muscle Strength (MEP, cmH2O)
|
93.89 cmH2O
Standard Deviation 30.70
|
76.67 cmH2O
Standard Deviation 23.51
|
SECONDARY outcome
Timeframe: assessed at discharge 6weekPopulation: Two-way repeated measures ANOVA for Modified Borg score.an intention-to-treat analysis was performed.group × time interactions were observed for the Modified Borg score
Dyspnea score as assessed by Modified Borg score, The literature review clearly showed that the Modified Borg score was a valid and reliable tool when used in pulmonary medicine and in exercise physiology studies.The scale used was perceived exertion adapted to be appropriate for measuring dyspnea. This consisted of a vertical scale labelled 0-10, with corresponding verbal expressions of progressively increasing perceived sensation intensity. It starts at number 0 that mean breathing is no difficulty at all and progresses through to number 10 that mean breathing difficulty is maximal.so higher scores mean a worse outcome
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 6 Weeks Modified Borg Score
|
0.75 scores on a scale
Standard Deviation 0.79
|
1.11 scores on a scale
Standard Deviation 1.74
|
SECONDARY outcome
Timeframe: assessed at discharge 6 weeksPopulation: Two-way repeated measures ANOVA for Lung expansion capacity. an intention-to-treat analysis was performed.group × time interactions were observed for the Lung expansion capacity
Lung expansion capacity as assessed by incentive spirometry with the flow-oriented device( Triflow II,volume × seconds) (ml)).Incentive spirometry that feedback respiratory training can improve respiratory function, endurance for exercise capacity,Wide flow rate range from 600 - 1200(volume × seconds) (mL)c.higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 6weeks Lung Expansion Capacity
|
1683.33 (ml)
Standard Deviation 667.96
|
1116.63 (ml)
Standard Deviation 382.33
|
SECONDARY outcome
Timeframe: at 6weeks after dischargePopulation: Pearson chi-square test was used for Pulmonary complication on discharge 6 weeks .Data is presented as n(%).
Pulmonary complication as assessed by Chest X-ray.pneumonia.lung collapse.atelectasis.emphysema and pleural effusion were collected.In our research,some patients have two pulmonary complications at the same time, such as emphysem and infiltration, so the total number is not necessarily equal to 18.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Postoperative 6weeks Pulmonary Complications
pneumonia
|
0 Participants
|
1 Participants
|
|
Postoperative 6weeks Pulmonary Complications
atelectasis
|
0 Participants
|
2 Participants
|
|
Postoperative 6weeks Pulmonary Complications
pleural effusion
|
3 Participants
|
4 Participants
|
|
Postoperative 6weeks Pulmonary Complications
emphysema
|
5 Participants
|
11 Participants
|
|
Postoperative 6weeks Pulmonary Complications
pulmonary infilation
|
1 Participants
|
1 Participants
|
SECONDARY outcome
Timeframe: assessments at discharge 12 weeksPopulation: .2-WAY repeated measures ANOVA method was used for pulmonary function test.
Forced vital capacity (FVC in (liter(L)/sec)) assessment by pulmonary function test.Normal values in healthy males aged 20-60 from 4.5-3.5 (liter(L)/sec),and for females from 3.25-2.5 (liter(L)/sec) ,and whether higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 12 Weeks Forced Vital Capacity (FVC in Liter(L)/Sec )
|
2.32 liter( L)/sec
Standard Deviation 0.72
|
2.16 liter( L)/sec
Standard Deviation 0.96
|
SECONDARY outcome
Timeframe: assessed at discharge12weeksPopulation: 2-WAY repeated measures ANOVA method was used for pulmonary function test.
The Forced Expiratory Volume in 1 Second parameter(FEV1,liter(L)/sec) measures the volume of air that was exhaled into the mouthpiece in the first second after a full inhalation. The Measured column represents the total volume exhaled during the first second, in liters. Normal values in healthy males aged 20-60 range from 4.5 to 3.5 liters, and normal values for females aged 20-60 range from 3.25 to 2.5 liters. The Predicted column compares the actual volume breathed out during the first second of your test to an average of the normal volume breathed out in 1 second for a person of the same gender, height, and age. This value is expressed as a percentage, with normal test values being between 80% and 120% of the average (predicted) values.and whether higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 12 Weeks Forced Expiratory Volume in 1 Second(FEV1,Liter(L)/Sec)
|
1.85 liter(L)/sec
Standard Deviation 0.45
|
1.74 liter(L)/sec
Standard Deviation 0.72
|
SECONDARY outcome
Timeframe: assessed at discharge12weeks "Population: 2-WAY repeated measures ANOVA method was used for pulmonary function test.
Forced expiratory flow (FEF) is the flow (or speed) of air coming out of the lung during the middle portion of a forced expiration. It can be given at discrete times, generally defined by what fraction of the forced vital capacity (FVC) has been exhaled. The usual discrete intervals are 25%, 50% and 75%, usually 25-75% (FEF25-75%).Predicted normal values for FEF depend on age, sex, height, mass and ethnicity as well as the research study that they are based on assessment by pulmonary function test and higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 12 Weeks MMEF 25-75%(Liter(L)/Sec)
|
2.44 liter(L)/sec
Standard Deviation 1.50
|
1.85 liter(L)/sec
Standard Deviation 0.76
|
SECONDARY outcome
Timeframe: assessed at discharge 12 weeksPopulation: 2-WAY repeated measures ANOVA method was used for pulmonary function test.
Peak expiratory flow rate (PEFR in liter(L)/sec) assessment by pulmonary function test.It measures the airflow through the bronchi and thus the degree of obstruction in the airways. Peak expiratory flow is typically measured in units of liters per second (L/sec).when measured as part of spirometry.The normal range 500-700 L/sec In men, for women, the normal range is 380-500 L/sec.higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 12 Weeks Peak Expiratory Flow Rate (PEFR in Liter(L)/Sec)
|
4.94 liter(L)/sec
Standard Deviation 1.46
|
4.78 liter(L)/sec
Standard Deviation 2.25
|
SECONDARY outcome
Timeframe: assessed at discharge12 weeks.Population: Two-way repeated measures ANOVA for MIP. an intention-to-treat analysis was performed.group × time interactions were observed for the MIP
Inspiratory muscle strength as assessed by Maximum inspiratory pressure (MIP, cmH2O).The MIP is a measure of inspiratory muscle strength produced by a sub-atmospheric pressure The normal.range of MIP in elderly people approximately 60 cm H2O for men and 40 cm H2O for women .An absolute MIP value of \< - 40 cm H2O is always abnormal,and higher scores was mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 12 Weeks Inspiratory Muscle Strength (MIP,cmH2O)
|
91.11 cmH2O
Standard Deviation 30.46
|
64.67 cmH2O
Standard Deviation 20.30
|
SECONDARY outcome
Timeframe: assessed at discharge 12weeksPopulation: Two-way repeated measures ANOVA for MEP. an intention-to-treat analysis was performed.group × time interactions were observed for the MEP
The Maximal Expiratory Pressure (MEP,cmH2O) are global measures of the maximal strength of the respiratory muscles.(MEP, cmH2O) .MEP is a supra-atmospheric pressure which can be developed in an effort of the abdominal and intercostal muscles.Expiratory muscle strength assesses extrathoracic muscle health.An absolute MEP value of \< 80 cm H2O is always abnormal, and higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 12weeks Expiratory Muscle Strength(MEP,cmH2O)
|
92.56 cmH2O
Standard Deviation 34.37
|
74.48 cmH2O
Standard Deviation 18.64
|
SECONDARY outcome
Timeframe: assessed at discharge12weeksPopulation: Two-way repeated measures ANOVA for Modified Borg score. an intention-to-treat analysis was performed.group × time interactions were observed for the Modified Borg score
Dyspnea score as assessed by Modified Borg score, The literature review clearly showed that the Modified Borg score was a valid and reliable tool when used in pulmonary medicine and in exercise physiology studies.The scale used was perceived exertion adapted to be appropriate for measuring dyspnea. This consisted of a vertical scale labelled 0-10, with corresponding verbal expressions of progressively increasing perceived sensation intensity. It starts at number 0 that mean breathing is no difficulty at all and progresses through to number 10 that mean breathing difficulty is maximal.so higher scores mean a worse outcome
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 12 Weeks Modified Borg Score
|
0.70 scores on a scale
Standard Deviation 0.83
|
1.05 scores on a scale
Standard Deviation 0.92
|
SECONDARY outcome
Timeframe: assessed at discharge 12weeksPopulation: Two-way repeated measures ANOVA for Lung expansion capacity. an intention-to-treat analysis was performed.group × time interactions were observed for the Lung expansion capacity
Lung expansion capacity as assessed by incentive spirometry with the flow-oriented device( Triflow II,volume × seconds) (ml)).Incentive spirometry that feedback respiratory training can improve respiratory function, endurance for exercise capacity,Wide flow rate range from 600 - 1200(volume × seconds) (mL)c.higher scores mean a better outcome.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Discharge 12 Weeks Lung Expansion Capacity
|
1406.67 (ml)
Standard Deviation 798.20
|
1150.33 (ml)
Standard Deviation 345.13
|
SECONDARY outcome
Timeframe: at 12 weeks after dischargePopulation: Pearson chi-square test was used for Pulmonary complication on discharge 12 weeks .Data is presented as n(%).
Pulmonary complication as assessed by Chest X-ray.pneumonia.lung collapse.atelectasis.emphysema and pleural effusion were collected.some patients have two pulmonary complications at the same time, such as emphysem and infiltration, so the total number is not necessarily equal to 18.
Outcome measures
| Measure |
Pulmonary Rehabilitation Group 2 Weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
The Control Group 2weeks Six-min Walking Distanc
n=18 Participants
Each subject received six-min walking distance assessments at discharge 2 weeks after discharge
|
|---|---|---|
|
Postoperative 12 Weeks Pulmonary Complications
pneumonia
|
0 Participants
|
1 Participants
|
|
Postoperative 12 Weeks Pulmonary Complications
atelectasis
|
1 Participants
|
2 Participants
|
|
Postoperative 12 Weeks Pulmonary Complications
pleural effusion
|
0 Participants
|
1 Participants
|
|
Postoperative 12 Weeks Pulmonary Complications
emphysema
|
1 Participants
|
0 Participants
|
|
Postoperative 12 Weeks Pulmonary Complications
pulmonary infilation
|
0 Participants
|
1 Participants
|
Adverse Events
Pulmonary Rehabilitation Group
The Control Group
Serious adverse events
Adverse event data not reported
Other adverse events
| Measure |
Pulmonary Rehabilitation Group
n=18 participants at risk
0-2 weeks, the aerobic exercise intensity was targeted to reach 10-11 points of RPE scale. Patients raised their upper limbs while simultaneously performing lower-limb stepping at place for 20 min; in addition, they walked at a comfortable speed for 15 min twice per day.Triflo-II was performed 8-10 times per hour. inspiratory muscle training (30 breaths each time, twice per day) with the initial pressure set at 25%-30% of the maximum inspiratory pressure.
3-6 weeks, the aerobic exercise intensity was targeted to reach 12-15 points on the RPE scale. Patients performed upper-limb resistance exercise (raising of a 250-cc water bottle) and lower-limb stepping for 20 min per day as well as walking exercise (slow walking for 5 min and fast walking for 2 min, followed by 5-min slow walking, for a total of 30 min).Triflo-II was performed 8-10 times per hour, and inspiratory muscle training, with the pressure intensity adjusted to more than 5% of that in the first stage.
|
The Control Group
n=18 participants at risk
The control group accept the pulmonary rehabilitation , breathing exercise, extremities exercise, breathing muscle training, incentive spirometry (Triflo-II) training, intermittent positive pressure ventilation, chest physical therapy and pain control) only in operation stage on before op-day 3 day and after op-day and without home based pulmonary rehabilitation.
|
|---|---|---|
|
Surgical and medical procedures
Prolonged air leak (PAL)
|
33.3%
6/18 • Number of events 18 • we collect 12 weeks of adverse event data
Before discharge,If air leakage occurs before discharge, we definition it as an adverse event, because it may extend the patient's hospital stay.After discharge, home-based rehabilitation program design as a low-to-medium intensity and non-invasive .Researchers contacted patients at home every week through phone calls to monitor the occurrence of any uncomfortable reaction and post-op 2weeks,6weeks and 12weeks regular check CXR .PFT. 6min walking test and respiratory muscle power .
|
33.3%
6/18 • Number of events 18 • we collect 12 weeks of adverse event data
Before discharge,If air leakage occurs before discharge, we definition it as an adverse event, because it may extend the patient's hospital stay.After discharge, home-based rehabilitation program design as a low-to-medium intensity and non-invasive .Researchers contacted patients at home every week through phone calls to monitor the occurrence of any uncomfortable reaction and post-op 2weeks,6weeks and 12weeks regular check CXR .PFT. 6min walking test and respiratory muscle power .
|
Additional Information
Respiratory therapist Nai-Ying Kuo
Chang Gung Memorial Hospital
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place