Trial Outcomes & Findings for fMRI Guided TMS Enhancement of Associative Memory Networks (NCT NCT02749422)

Last Updated: 2024-05-29

Results Overview

A face-object pair association task will be administered before and after rTMS treatment at each treatment session. This measure is evaluating the mean change in the task score from immediately before rTMS is applied to the left lateral parietal site to immediately after treatment.

Recruitment status

TERMINATED

Study phase

Target enrollment

8 participants

Primary outcome timeframe

Immediately before Left Lateral Parietal Site Stimulation, Immediately after Left Lateral Parietal Site Stimulation (20 minute procedure; Up to Week 6)

Results posted on

2024-05-29

Participant Flow

No patients were enrolled in the Healthy Subjects arm.

Participant milestones

Participant milestones
Measure	Healthy Subjects MagStim RapidStim2: Repetitive transcranial magnetic stimulation (TMS)	Temporal Lobe Epilepsy Patients MagStim RapidStim2: Repetitive transcranial magnetic stimulation (TMS)
Overall Study STARTED	0	8
Overall Study COMPLETED	0	5
Overall Study NOT COMPLETED	0	3

Reasons for withdrawal

Reasons for withdrawal
Measure	Healthy Subjects MagStim RapidStim2: Repetitive transcranial magnetic stimulation (TMS)	Temporal Lobe Epilepsy Patients MagStim RapidStim2: Repetitive transcranial magnetic stimulation (TMS)
Overall Study Lost to Follow-up	0	2
Overall Study Ineligible	0	1

Baseline Characteristics

fMRI Guided TMS Enhancement of Associative Memory Networks

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Healthy Subjects MagStim RapidStim2: Repetitive transcranial magnetic stimulation (TMS)	Temporal Lobe Epilepsy Patients n=5 Participants MagStim RapidStim2: Repetitive transcranial magnetic stimulation (TMS)	Total n=5 Participants Total of all reporting groups
Age, Continuous	—	26.6 years STANDARD_DEVIATION 7.3 • n=7 Participants	26.6 years STANDARD_DEVIATION 7.3 • n=5 Participants
Sex: Female, Male Female	—	4 Participants n=7 Participants	4 Participants n=5 Participants
Sex: Female, Male Male	—	1 Participants n=7 Participants	1 Participants n=5 Participants
Ethnicity (NIH/OMB) Hispanic or Latino	—	0 Participants n=7 Participants	0 Participants n=5 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	—	1 Participants n=7 Participants	1 Participants n=5 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	—	4 Participants n=7 Participants	4 Participants n=5 Participants
Race (NIH/OMB) American Indian or Alaska Native	—	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Asian	—	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	—	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Black or African American	—	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) White	—	1 Participants n=7 Participants	1 Participants n=5 Participants
Race (NIH/OMB) More than one race	—	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Unknown or Not Reported	—	4 Participants n=7 Participants	4 Participants n=5 Participants
Region of Enrollment United States	—	5 participants n=7 Participants	5 participants n=5 Participants

PRIMARY outcome

Timeframe: Immediately before Left Lateral Parietal Site Stimulation, Immediately after Left Lateral Parietal Site Stimulation (20 minute procedure; Up to Week 6)