Metformin Induces a Dietary Restriction-like State in Human
NCT ID: NCT02745886
Last Updated: 2016-04-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
60 participants
INTERVENTIONAL
2016-04-30
2016-12-31
Brief Summary
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Sixty overweight subjects will be included in this study, and participants will be divided 3 groups (20 cases in each group)including metformin group (0.85, twice daily), standard diet group, and CR group. All subjects will be treated 6 months. At the end of this study, blood samples and muscle samples will be obtained.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Metformin group
Metformin 0.85 twice daily for 6 months
metformin 0.85 twice daily for 6 months
Standard diet group
No interventions assigned to this group
CR group
Calorie restriction diet will be given to this group.
Calorie restriction
Interventions
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metformin 0.85 twice daily for 6 months
Calorie restriction
Eligibility Criteria
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Inclusion Criteria
* Male
Exclusion Criteria
* Obesity
* Using any other drugs
* \< 18 years old
* \> 60 years old
* Mental disorders
* Surgery history for abdomen
18 Years
60 Years
MALE
Yes
Sponsors
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Xiang Guang-da
OTHER
Responsible Party
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Xiang Guang-da
Director of Endocrinol Dept.
Principal Investigators
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Guangda Xiang, MD,PhD
Role: STUDY_CHAIR
Wuhan General Hospital
Locations
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Zhang Jiajia
Wuhan, Hubei, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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Wze2016009
Identifier Type: -
Identifier Source: org_study_id
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