Trial Outcomes & Findings for Forced-air Warming in Endovascular Surgery: Testing Effectiveness of Two Different Blanket Models (NCT NCT02742818)

NCT ID: NCT02742818

Last Updated: 2019-12-30

Results Overview

After tracheal intubation, upper body or underbody blanket will be turned on at the highest temperature of the warming unit ( 43 celsius degree) and the body temperatures will be measured and registered with an esophageal thermometer every 15 minutes until tracheal extubation. Temperatures will be compared with the purposes of determining which one of the two models tested are more effective in keeping patient warm. Values of body temperature across duration of surgery will be compared by models of variance analysis with repeated measurements. Duration of surgery will be used as a control variable.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

50 participants

Primary outcome timeframe

Across duration of surgery (up to 210 minutes)

Results posted on

2019-12-30

Participant Flow

Participant milestones

Participant milestones
Measure
Upper Body Blanket
Patients undergoing EVAR and LEA will use this type of warming blanket. 522 upper body blanket, Bair Hugger, 3M
Underbody Blanket
Patients undergoing EVAR and LEA will use this type of warming blanket. 635 full access underbody blanket, Bair Hugger, 3M
Overall Study
STARTED
25
25
Overall Study
COMPLETED
25
23
Overall Study
NOT COMPLETED
0
2

Reasons for withdrawal

Reasons for withdrawal
Measure
Upper Body Blanket
Patients undergoing EVAR and LEA will use this type of warming blanket. 522 upper body blanket, Bair Hugger, 3M
Underbody Blanket
Patients undergoing EVAR and LEA will use this type of warming blanket. 635 full access underbody blanket, Bair Hugger, 3M
Overall Study
Adverse Event
0
1
Overall Study
Protocol Violation
0
1

Baseline Characteristics

Forced-air Warming in Endovascular Surgery: Testing Effectiveness of Two Different Blanket Models

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Underbody Blanket
n=23 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 635 full access underbody blanket, Bair Hugger, 3M
Upper Body Blanket
n=25 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 522 upper body blanket, Bair Hugger, 3M
Total
n=48 Participants
Total of all reporting groups
Age, Continuous
71 years
n=5 Participants
70 years
n=7 Participants
70.5 years
n=5 Participants
Sex: Female, Male
Female
8 Participants
n=5 Participants
6 Participants
n=7 Participants
14 Participants
n=5 Participants
Sex: Female, Male
Male
15 Participants
n=5 Participants
19 Participants
n=7 Participants
34 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Across duration of surgery (up to 210 minutes)

Population: In the Underbody blanket group 2 patients were excluded from analysis. One of the patients due to anaphylactic reaction and the other framed exclusion criteria (Surgery time lesser than 45 minutes)

After tracheal intubation, upper body or underbody blanket will be turned on at the highest temperature of the warming unit ( 43 celsius degree) and the body temperatures will be measured and registered with an esophageal thermometer every 15 minutes until tracheal extubation. Temperatures will be compared with the purposes of determining which one of the two models tested are more effective in keeping patient warm. Values of body temperature across duration of surgery will be compared by models of variance analysis with repeated measurements. Duration of surgery will be used as a control variable.

Outcome measures

Outcome measures
Measure
Upper Body Blanket
n=25 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 522 upper body blanket, Bair Hugger, 3M
Underbody Blanket
n=23 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 635 full access underbody blanket, Bair Hugger, 3M
Values of Body Temperature ( in Celsius Degree ) in Two Groups of Patients Undergoing EVAR and LEA That Will Use Two Different Types of Bair Hugger 3M Body Warming Blankets, Namely: 522 Upper Body Blanket and 635 Full Access Underbody Blanket.
36.2 Celsius degrees
Interval 35.1 to 37.3
36.1 Celsius degrees
Interval 34.3 to 37.1

SECONDARY outcome

Timeframe: At time of surgery ( in minutes)

The investigators will observe the profile of the patients and the mean of age in two groups.

Outcome measures

Outcome measures
Measure
Upper Body Blanket
n=25 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 522 upper body blanket, Bair Hugger, 3M
Underbody Blanket
n=23 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 635 full access underbody blanket, Bair Hugger, 3M
Age ( in Years)
70 years
Interval 62.0 to 73.0
71 years
Interval 60.5 to 76.5

SECONDARY outcome

Timeframe: At time of surgery ( in minutes)

The investigators will observe gender distribution in the two groups studied.

Outcome measures

Outcome measures
Measure
Upper Body Blanket
n=23 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 522 upper body blanket, Bair Hugger, 3M
Underbody Blanket
n=25 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 635 full access underbody blanket, Bair Hugger, 3M
Gender
Female
8 Participants
6 Participants
Gender
Male
15 Participants
19 Participants

SECONDARY outcome

Timeframe: At time of surgery ( in minutes)

The investigators will observe the type of surgery distribution profile in the two groups studied.

Outcome measures

Outcome measures
Measure
Upper Body Blanket
n=25 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 522 upper body blanket, Bair Hugger, 3M
Underbody Blanket
n=23 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 635 full access underbody blanket, Bair Hugger, 3M
Type of Surgery ( LEA and EVAR )
EVAR
13 Participants
12 Participants
Type of Surgery ( LEA and EVAR )
LEA
12 Participants
11 Participants

SECONDARY outcome

Timeframe: Across duration of surgery ( in minutes)

Population: Models of generalized estimation equations will be used to evaluate the evolution of body temperature across duration of surgery (in minutes)

The investigators will observe the duration of surgery (in minutes) in the two groups studied.

Outcome measures

Outcome measures
Measure
Upper Body Blanket
n=25 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 522 upper body blanket, Bair Hugger, 3M
Underbody Blanket
n=23 Participants
Patients undergoing EVAR and LEA will use this type of warming blanket. 635 full access underbody blanket, Bair Hugger, 3M
Duration of Surgery ( in Minutes)
180 minutes
Interval 150.0 to 210.0
210 minutes
Interval 135.0 to 232.5

Adverse Events

Upper Body Blanket

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Underbody Blanket

Serious events: 1 serious events
Other events: 1 other events
Deaths: 0 deaths

Serious adverse events

Serious adverse events
Measure
Upper Body Blanket
n=25 participants at risk
Patients undergoing EVAR and LEA will use this type of warming blanket. 522 upper body blanket, Bair Hugger, 3M
Underbody Blanket
n=25 participants at risk
Patients undergoing EVAR and LEA will use this type of warming blanket. 635 full access underbody blanket, Bair Hugger, 3M
Immune system disorders
Anaphylatic reaction
0.00%
0/25
4.0%
1/25 • Number of events 1

Other adverse events

Other adverse events
Measure
Upper Body Blanket
n=25 participants at risk
Patients undergoing EVAR and LEA will use this type of warming blanket. 522 upper body blanket, Bair Hugger, 3M
Underbody Blanket
n=25 participants at risk
Patients undergoing EVAR and LEA will use this type of warming blanket. 635 full access underbody blanket, Bair Hugger, 3M
Immune system disorders
Anaphylatic reaction
0.00%
0/25
4.0%
1/25 • Number of events 1

Additional Information

Dr. Nelson Wolosker

Hospital Israelita Albert Einstein

Phone: +55 11 2151-5423

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place