High Flow Nasal Cannula Use in Infants With Bronchiolitis
NCT ID: NCT02737280
Last Updated: 2018-12-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
TERMINATED
NA
18 participants
INTERVENTIONAL
2016-03-31
2018-09-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
High Flow in Infants With Bronchiolitis
NCT02913040
High-flow Nasal Oxygen Therapy in Hospitalized Infant With Moderate-to-severe Bronchiolitis
NCT02856165
High Flow Nasal Cannula vs Low Flow Oxygen Therapy in Bronchiolitis
NCT03015051
Comparison of Oxygen Adminstration by Nasal Cannula and High Flow Cannula During Bronchoscopy
NCT03976167
High Flow Nasal Cannula Weaning in Acute Bronchiolitis
NCT06321133
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
The investigators will recruit 160 infants who require oxygen therapy (oxygen saturation \<92%) during hospitalization due to a viral bronchiolitis. The participants are randomized to receive oxygen therapy either with high flow or ordinary nasal cannula.The infants are closely observed by study physicians for clinical parameters. The primary end point is treatment failure (need for change of respiratory support method). Secondary endpoints are respiratory rate (RR) and oxygen saturation (%) at specific measuring points, time from randomisation to end of oxygen therapy and time from randomisation to discharge.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Usual oxygen therapy
Oxygen therapy with normal nasal cannula (for example MedKit Finland) 0-2 l/min
MedKit Finland - Usual oxygen therapy
Oxygen therapy with normal nasal cannula (for example MedKit Finland) 0-2 l/min
High flow oxygen therapy
High flow nasal cannula oxygen therapy with Airvo (TM, Fisher \& Paykel Healthcare) device
Airvo (TM, Fisher & Paykel Healthcare) - High flow oxygen therapy
High flow nasal cannula therapy with Airvo (TM, Fisher \& Paykel Healthcare) device
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Airvo (TM, Fisher & Paykel Healthcare) - High flow oxygen therapy
High flow nasal cannula therapy with Airvo (TM, Fisher \& Paykel Healthcare) device
MedKit Finland - Usual oxygen therapy
Oxygen therapy with normal nasal cannula (for example MedKit Finland) 0-2 l/min
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Need of oxygen therapy (oxygen saturation \< 92%)
Exclusion Criteria
* Needs intubation or CPAP on admission
* Severe congenital heart defect
* Down's syndrome
6 Months
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Oulu
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Marjo Renko
MD, PhD
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Marjo Renko, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Oulu
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Central Hospital Jyväskylä
Jyväskylä, , Finland
Oulu Unversity Hospital
Oulu, , Finland
Seinäjoki Central Hospital
Seinäjoki, , Finland
Tampere University Hospital
Tampere, , Finland
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
EETTMK2015
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.