Tranexamic Acid in Hip Fracture Surgery

NCT ID: NCT02736383

Last Updated: 2023-09-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

142 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-05-31

Study Completion Date

2017-07-31

Brief Summary

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To determine if TXA utilization is effective at reducing transfusion rates in elderly patients undergoing surgery for treatment of a hip fractures.

Detailed Description

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Conditions

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Hip Fracture

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Tranexamic Acid

Patients that receive 2 gm TXA during surgery

No interventions assigned to this group

No Tranexamic Acid

Patients that receive no TXA during surgery

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Acute, isolated, unilateral femoral neck, intertrochanteric, and per trochanteric hip fractures confirmed by anteroposterior/lateral hip radiographs, computed tomography, or magnetic resonance imaging.
* Age 65 and older
* Low energy mechanism of injury
* Hip fracture fixation performed within 48 hours
* English speaking
* Anticipated medical optimization for operative fixation
* No other major trauma

Exclusion Criteria

* Retained hardware around the affected hip
* Infection around the affected hip
* Transfer patients with a length of stay \> 24 hours at the transferring hospital
* Diagnosis of deficient natural anticoagulation
* Known congenital thrombophilia (Deficiency of Protein C, S, Antithrombin)
* Known allergy to TXA
* Patients undergoing percutaneous pinning of the hip fracture
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Spectrum Health Hospitals

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Blake W Miller, DO

Role: PRINCIPAL_INVESTIGATOR

Spectrum Health Hospitals

Other Identifiers

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2016-060

Identifier Type: -

Identifier Source: org_study_id

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