Rg3 in Combination With TACE in Hepatocellular Carcinoma Patients With High Expression of Notch1
NCT ID: NCT02724358
Last Updated: 2016-03-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
320 participants
INTERVENTIONAL
2012-12-31
2015-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Keywords
Explore important study keywords that can help with search, categorization, and topic discovery.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
TACE
iodized oil (5ml) + Pirarubicin (20mg)
TACE
iodized oil (5ml) + Pirarubicin (20mg)
Rg3
20mg, BID, maintained though Month 12
Rg3
20mg, BID, maintained though Month 12.
TACE + Rg3
the combination of the treatments for the above two groups. Rg3 will be stopped on the day performing TACE.
TACE + Rg3
Control
standard liver protective therapy
protective therapy
standard liver protective therapy
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
TACE
iodized oil (5ml) + Pirarubicin (20mg)
Rg3
20mg, BID, maintained though Month 12.
TACE + Rg3
protective therapy
standard liver protective therapy
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
2. High expression of Notch1 in tumor tissues.
Exclusion Criteria
18 Years
80 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Eastern Hepatobiliary Surgery Hospital
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
ShenFeng
vice president of the Eastern Hepatobiliary Surgery Hospital
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Eastern hepatobilliary surgery hospital
Shanghai, Shanghai Municipality, China
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2012ZX10002016008
Identifier Type: -
Identifier Source: org_study_id