OTIVACTO Regional Center Vienna (RCV) Non-Interventional Study (NIS)

NCT ID: NCT02719639

Last Updated: 2019-01-09

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

7443 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-04-01

Study Completion Date

2017-05-31

Brief Summary

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Real-world data on the effects of a fixed-dose combination Long-acting beta agonists + long-acting antimuscarinic agent (LABA+LAMA) therapy with tiotropium and olodaterol administered in a single device, in COPD patients who need treatment with two long-acting bronchodilators, is not available. This is a self-controlled study design enrolling consented COPD patients who will be treated with Spiolto Respimat according to the approved Summary of Product Characteristics (SmPC).

Detailed Description

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Purpose:

Study Design:

Conditions

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Pulmonary Disease, Chronic Obstructive

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Written informed consent prior to participation
2. Female and male patients with more or equal to 40 years of age
3. Patients diagnosed with COPD and requiring long-acting dual bronchodilation (LAMA + LABA) treatment according to approved Spiolto Respimat Summary of Product Characteristics (SmPC) and chronic obstructive pulmonary disease (COPD) Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline recommendation

Exclusion Criteria

1. Patients with contraindications according to Spiolto Respimat SmPC
2. Patients who have been treated with a LABA/LAMA combination (free and fixed dose) in the previous 6 months
3. Patients continuing LABA- Inhalative Corticosteroids (ICS) treatment should not be additionally treated with Spiolto Respimat in order to avoid a double dosing of long-acting beta-agonists
4. Patients for whom further follow-up is not possible at the enrolling site during the planned study period of approx. 6 weeks
5. Pregnancy and lactation
6. Patients currently listed for lung transplantation
7. Current participation in any clinical trial or any other non-interventional study of a drug or device
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boehringer Ingelheim

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Boehringer Ingelheim

Role: STUDY_CHAIR

Boehringer Ingelheim

Locations

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Multiple Locations, , Austria

Site Status

Multiple Locations, , Czechia

Site Status

Multiple Locations, , Hungary

Site Status

Multiple Locations, , Israel

Site Status

Multiple Locations, , Romania

Site Status

Multiple Locations, , Russia

Site Status

Multiple Locations, , Slovakia

Site Status

Multiple Locations, , Slovenia

Site Status

Multiple Locations, , Switzerland

Site Status

Countries

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Austria Czechia Hungary Israel Romania Russia Slovakia Slovenia Switzerland

References

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Taube C, Bayer V, Zehendner CM, Valipour A. Assessment of Patient Experiences with Respimat(R) in Everyday Clinical Practice. Pulm Ther. 2020 Dec;6(2):371-380. doi: 10.1007/s41030-020-00127-4. Epub 2020 Aug 28.

Reference Type DERIVED
PMID: 32857327 (View on PubMed)

Provided Documents

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Document Type: Statistical Analysis Plan

View Document

Document Type: Study Protocol

View Document

Other Identifiers

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1237.44

Identifier Type: -

Identifier Source: org_study_id

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