Registry Study on Primary Ciliary Dyskinesia in Chinese Children

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-05-31

Study Completion Date

2030-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study is a multicenter, prospective cohort study of patients diagnosed with primary ciliary dyskinesia, the clinical information of recruited patients, including clinical manifestations, lung function, chest imaging, quality of life and other indicators, will be followed for 10 years.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Status Quo of Diagnosis and Treatment of Pediatric Outpatients With Respiratory Diseases

NCT04855604

Respiratory Diseases

UNKNOWN

Examining Bronchial Hyperresponsiveness in Primary Ciliary Dyskinesia

NCT07288827

Primary Ciliary Dyskinesia Healthy

RECRUITING NA

Study the Diagnostic and Therapeutic Role of Flexible Bronchoscopy in the Patients Attending Assuit University Children Hospita

NCT07043309

Chest Disorder

NOT_YET_RECRUITING

Bedside Lung Ultrasound in Young Children Presenting to the Emergency Department (ED) With Wheezing

NCT01452945

Wheezing Bronchiolitis

COMPLETED

Impact of Respiratory Physiotherapy in Children With Bronchiolitis in the First Two Years of Life

NCT02708147

Bronchiolitis

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

All new cases of primary ciliary dyskinesia which was confirmed or diagnosed at each center from the beginning of the study are made the investigation of the clinical manifestations and specific tests by the standard diagnostic process.Then all the patients' following clinical data will be followed for 10 years (once per six month): clinical manifestations, lung function, chest imaging (once per year), quality of life and other indicators.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Primary Ciliary Dyskinesia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age 0\~18 years old
* Any organ system symptoms consistent with PCD and being conform to the clinical diagnostic standard of Katergener syndrome or being coincident with at least two following specific tests:
* Abnormal ciliary beat frequency or movement by the high speed photography microscope
* Abnormal ciliary structure through the electronic microscopy
* The nasal NO decreased significantly
* The target gene mutation found
* The clinical diagnostic criteria of the Katergener syndrome: ① bronchial expansion; ② sinusitis or nasal polyps; ③ transposition of viscera and (or) dextrocardia.
* If all the typical clinical manifestations but only 1 specific test with positive results, can also be included in the registration of suspected PCD cases
* Consent to provide the related clinical specimen to the certain hospital
* The guardians of the patients fully understand the purpose of the study, volunteer their children to participate in this study, and sign informed consent.

Exclusion Criteria

* It is unable to provide complete medical records or the current condition can not accept the diagnosis process
* She or he cannot agree to participate in the study.

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No