Trial Outcomes & Findings for Protection Against Potential Brain Injury During Competitive Football (NCT NCT02696200)

NCT ID: NCT02696200

Last Updated: 2020-12-09

Results Overview

monitor the differences in average number of hits between the group wearing the collar and the group not wearing the collar

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

62 participants

Primary outcome timeframe

5 months

Results posted on

2020-12-09

Participant Flow

Participant milestones

Participant milestones
Measure
Subjects Wearing the Q Collar
Subjects wearing the Q collar throughout the football season Q Collar: The device is fitted to the neck to provide a comfortable and precise jugular compression that potentially mitigates cerebral slosh. The device will be worn inside the collar of an athletic compression shirt.
Subjects Not Wearing the Q Collar
Control group of subjects not wearing the q collar
Overall Study
STARTED
32
30
Overall Study
COMPLETED
32
30
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Subjects Wearing the Q Collar
n=32 Participants
Subjects wearing the Q collar throughout the football season Q Collar: The device is fitted to the neck to provide a comfortable and precise jugular compression that potentially mitigates cerebral slosh. The device will be worn inside the collar of an athletic compression shirt.
Subjects Not Wearing the Q Collar
n=30 Participants
Control group of subjects not wearing the q collar
Total
n=62 Participants
Total of all reporting groups
Age, Categorical
<=18 years
32 Participants
n=32 Participants
30 Participants
n=30 Participants
62 Participants
n=62 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=32 Participants
0 Participants
n=30 Participants
0 Participants
n=62 Participants
Age, Categorical
>=65 years
0 Participants
n=32 Participants
0 Participants
n=30 Participants
0 Participants
n=62 Participants
Sex: Female, Male
Female
0 Participants
n=32 Participants
0 Participants
n=30 Participants
0 Participants
n=62 Participants
Sex: Female, Male
Male
32 Participants
n=32 Participants
30 Participants
n=30 Participants
62 Participants
n=62 Participants
Race and Ethnicity Not Collected
0 Participants
Race and Ethnicity were not collected from any participant.
Region of Enrollment
United States
32 participants
n=32 Participants
30 participants
n=30 Participants
62 participants
n=62 Participants

PRIMARY outcome

Timeframe: 5 months

monitor the differences in average number of hits between the group wearing the collar and the group not wearing the collar

Outcome measures

Outcome measures
Measure
Subjects Wearing the Q Collar
n=32 Participants
Subjects wearing the Q collar throughout the football season Q Collar: The device is fitted to the neck to provide a comfortable and precise jugular compression that potentially mitigates cerebral slosh. The device will be worn inside the collar of an athletic compression shirt.
Subjects Not Wearing the Q Collar
n=30 Participants
Control group of subjects not wearing the q collar
Determine Average Number of Hits Between Groups
Avg # of hits >20g
896.43 number of hits
Standard Deviation 600.03
795.40 number of hits
Standard Deviation 508.92
Determine Average Number of Hits Between Groups
Avg # of hits >50g
144.67 number of hits
Standard Deviation 106.55
145.85 number of hits
Standard Deviation 109.98
Determine Average Number of Hits Between Groups
Avg # of hits >100g
14.38 number of hits
Standard Deviation 11.29
18.3 number of hits
Standard Deviation 20.85
Determine Average Number of Hits Between Groups
Avg # of hits >150g
2.43 number of hits
Standard Deviation 3.11
1.8 number of hits
Standard Deviation 2.04
Determine Average Number of Hits Between Groups
Avg # of hits >200g
0.43 number of hits
Standard Deviation 1.17
0.30 number of hits
Standard Deviation 0.73

PRIMARY outcome

Timeframe: 5 months

determine the number of subjects in the collar group and the non collar group that underwent EEG assessment

Outcome measures

Outcome measures
Measure
Subjects Wearing the Q Collar
n=32 Participants
Subjects wearing the Q collar throughout the football season Q Collar: The device is fitted to the neck to provide a comfortable and precise jugular compression that potentially mitigates cerebral slosh. The device will be worn inside the collar of an athletic compression shirt.
Subjects Not Wearing the Q Collar
n=30 Participants
Control group of subjects not wearing the q collar
Number of Participants Undergoing EEG Assessment
32 Participants
30 Participants

PRIMARY outcome

Timeframe: 6 months

Change in fractional anisotropy (FA) from Pre to Post season

Outcome measures

Outcome measures
Measure
Subjects Wearing the Q Collar
n=32 Participants
Subjects wearing the Q collar throughout the football season Q Collar: The device is fitted to the neck to provide a comfortable and precise jugular compression that potentially mitigates cerebral slosh. The device will be worn inside the collar of an athletic compression shirt.
Subjects Not Wearing the Q Collar
n=30 Participants
Control group of subjects not wearing the q collar
Change in Fractional Anisotropy (FA)
0.03 percentage of change
Standard Deviation 1.24
2.43 percentage of change
Standard Deviation 1.01

Adverse Events

Subjects Wearing the Q Collar

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Subjects Not Wearing the Q Collar

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Kim Foss

Cincinnati Childrens Hospital

Phone: 513-636-5971

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place