A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of HCP1303 Capsules

NCT ID: NCT02667938

Last Updated: 2016-10-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

510 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-03-31

Study Completion Date

2016-05-31

Brief Summary

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The main objective of this study is to evaluate efficacy and safety of HCP1301 capsule in patients with Benign Prostatic Hyperplasia and Erectile Dysfunction

Detailed Description

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A multicenter, randomized, double-blind, phase 3 clinical trial to evaluate the efficacy and safety of HCP1303 capsule

Conditions

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Benign Prostatic Hyperplasia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Treatment 1

HCP1303 capsule 5/0.2mg + HCP1303 capsule 5/0.4mg placebo+ HGP1201 placebo

Group Type EXPERIMENTAL

HCP1303 capsule 5/0.2mg

Intervention Type DRUG

HCP1303 capsule 5/0.4mg placebo

Intervention Type DRUG

HGP1201 placebo

Intervention Type DRUG

Treatment 2

HCP1303 capsule 5/0.2mg placebo+ HCP1303 capsule 5/0.4mg + HGP1201 placebo

Group Type EXPERIMENTAL

HCP1303 capsule 5/0.4mg

Intervention Type DRUG

HCP1303 capsule 5/0.2mg placebo

Intervention Type DRUG

HGP1201 placebo

Intervention Type DRUG

Active Comparator

HCP1303 capsule 5/0.2mg placebo+ HCP1303 capsule 5/0.4mg placebo+ HGP1201

Group Type ACTIVE_COMPARATOR

HGP1201

Intervention Type DRUG

HCP1303 capsule 5/0.2mg placebo

Intervention Type DRUG

HCP1303 capsule 5/0.4mg placebo

Intervention Type DRUG

Interventions

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HCP1303 capsule 5/0.2mg

Intervention Type DRUG

HCP1303 capsule 5/0.4mg

Intervention Type DRUG

HGP1201

Intervention Type DRUG

HCP1303 capsule 5/0.2mg placebo

Intervention Type DRUG

HCP1303 capsule 5/0.4mg placebo

Intervention Type DRUG

HGP1201 placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* At Visit 1

1. ≥50 age
2. BPH(Benign Prostatic Hyperplasia) + Total IPSS(International Prostate Symptom Score) ≥ 13
3. Abnormal Erectile function ≥ at least 3months based on screening date
* At Visit 2 1. Total IPSS ≥ 13

Exclusion Criteria

1. History of hypersensitivity to Tamsulosin or Tadalafil
2. History of allergy for Sulfonamide
3. PSA (Prostate Specific Antigen) ≥4ng/mL
Minimum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Hanmi Pharmaceutical Company Limited

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Se Woong Kim, M.D.,Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Catholic University of Seoul St.Mary's Hospital

Other Identifiers

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HM-TASU-301

Identifier Type: -

Identifier Source: org_study_id

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