Nasal Swab studyComparison of Effectiveness of Povidone-iodine Versus Saline Versus 3M Skin and Nasal Antiseptic 5% Povidone-Iodine USP Swabs for Decolonizing Intranasal MSSA/MRSA

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Brief Summary

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To determine if routinely available 10% povidone-iodine swabs are more effective than saline and 3M Skin and Nasal Antiseptic 5% Povidone-Iodine USP for decolonizing MRSA.

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Detailed Description

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Conditions

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MRSA/ MSSA Colonization of the Nares

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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povidone-iodine

Group Type ACTIVE_COMPARATOR

Povidone-Iodine

Intervention Type DRUG

3M Skin and Nasal Antiseptic 5% Povidone-Iodine USP swabs

Group Type ACTIVE_COMPARATOR

5% Povidone-Iodine USP swabs

Intervention Type DRUG

Saline

Group Type PLACEBO_COMPARATOR

Saline

Intervention Type DRUG

Interventions

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Saline

Intervention Type DRUG

Povidone-Iodine

Intervention Type DRUG

5% Povidone-Iodine USP swabs

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. All potential total hip and total knee arthroplasty candidates
2. All femoroacetabular osteoplasty patients
3. All pelvic acetabular osteotomy patients
4. All core decompression patients

Exclusion Criteria

1. Any trauma patients
2. Any tumor patients
3. Any patient with periprosthetic joint infection
4. Any patient with surgical site infection
5. Any patient with known MRSA infection
6. Any patients allergic to povidone-iodine
7. Patients with thyroid disease

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No