Trial Outcomes & Findings for Changes in Cerebral Oxygenation Based on Intraoperative Ventilation Strategy (NCT NCT02651103)

NCT ID: NCT02651103

Last Updated: 2018-10-15

Results Overview

Measured on the NIRS cerebral oxygenation monitor attached to the patient

Recruitment status

COMPLETED

Target enrollment

30 participants

Primary outcome timeframe

prior to induction of anesthesia in the awake patient and following four ventilation strategies (average time frame of 15 mins. to 5 hours)

Results posted on

2018-10-15

Participant Flow

Participant milestones

Participant milestones
Measure
Posterior Spinal Fusion
Patients undergoing spinal fusion surgery NIRS: Cerebral oxygenation monitor which is standard of care for this surgery.
Overall Study
STARTED
30
Overall Study
COMPLETED
30
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Posterior Spinal Fusion
n=30 Participants
Patients undergoing spinal fusion surgery NIRS: Cerebral oxygenation monitor which is standard of care for this surgery.
Age, Categorical
<=18 years
30 Participants
n=30 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=30 Participants
Age, Categorical
>=65 years
0 Participants
n=30 Participants
Sex: Female, Male
Female
17 Participants
n=30 Participants
Sex: Female, Male
Male
13 Participants
n=30 Participants
Region of Enrollment
United States
30 participants
n=30 Participants

PRIMARY outcome

Timeframe: prior to induction of anesthesia in the awake patient and following four ventilation strategies (average time frame of 15 mins. to 5 hours)

Measured on the NIRS cerebral oxygenation monitor attached to the patient

Outcome measures

Outcome measures
Measure
Posterior Spinal Fusion
n=30 Participants
Patients undergoing spinal fusion surgery NIRS: Cerebral oxygenation monitor which is standard of care for this surgery.
Change in Cerebral Oxygenation Values Throughout the Procedure
Phase 1
83 rSO2
Standard Deviation 8
Change in Cerebral Oxygenation Values Throughout the Procedure
Phase 2
79 rSO2
Standard Deviation 8
Change in Cerebral Oxygenation Values Throughout the Procedure
Phase 3
81 rSO2
Standard Deviation 9
Change in Cerebral Oxygenation Values Throughout the Procedure
Phase 4
83 rSO2
Standard Deviation 8

Adverse Events

Posterior Spinal Fusion

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Clinical Research Coordinator

Nationwide Children's Hospital

Phone: 6147222997

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place