Pupillary Dilation After Incremental Tetanic Stimulations Under Ketamine Sedation
NCT ID: NCT02648412
Last Updated: 2016-12-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
24 participants
INTERVENTIONAL
2012-04-30
2013-04-30
Brief Summary
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After an intravenous bolus of 1 mg/kg of ketamine, tetanic stimulations were performed every minute at increasing intensities of 10, 20, 30, 40 and 60 milliamps (similar to the stimulations of neuromuscular blocking agents monitoring). Pupillary diameter was measured before and after each stimulation.
Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Ketamine sedation
Procedure scheduled under ketamine sedation. Baseline pupillary diameter measurement in alert subjects. Injection of a bolus of 1 mg/kg of ketamine. Every minute, tetanic stimulations of incremental intensities (10-20-30-40-60 milliamps), during 5 seconds.
Pupillary diameter measurement before and after each stimulation. End of study period, beginning of procedure.
ketamine
bolus 1 mg/kg
Tetanic stimulations of incremental intensities
10-20-30-40-60 milliamps on the patient's left forearm
Interventions
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ketamine
bolus 1 mg/kg
Tetanic stimulations of incremental intensities
10-20-30-40-60 milliamps on the patient's left forearm
Eligibility Criteria
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Inclusion Criteria
* Burnt skin area 5-40%
* Scheduled for a dressing change under ketamine sedation
Exclusion Criteria
2 Years
18 Years
ALL
No
Sponsors
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Pr Isabelle CONSTANT
OTHER
Responsible Party
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Pr Isabelle CONSTANT
Professor
Principal Investigators
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Isabelle Constant, PHD
Role: STUDY_DIRECTOR
University Hospital Armand Trousseau
Locations
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Departement d'anesthesie Hopital Armand Trousseau
Paris, , France
Countries
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Other Identifiers
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Pupillo ketamine
Identifier Type: -
Identifier Source: org_study_id