Project-0027. Lay User Usage Study

NCT ID: NCT02636166

Last Updated: 2015-12-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

943 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-07-31

Study Completion Date

2015-12-31

Brief Summary

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Study volunteers will be required to conduct a home pregnancy test (HPT) at the trial centre and provide a sample of urine from the same void for further testing.

Volunteers will then complete a product usage questionnaire and leaflet comprehension questionnaire at site.

Follow-up information will be required from all volunteers as both additional urine sample(s) and pregnancy information to establish true pregnancy status at the study visit.

Detailed Description

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Eligible volunteers will be recruited into the study and provide informed consent. Volunteers will then test their urine sample with the investigational HPT according to the device Instructions for use and record their result onto the results sheet. A sample of urine from the same void will be obtained for further testing by the study technicians.

The technician will then test the volunteer's sample with a second investigational HPT, a professional use pregnancy test and a Clearblue Digital HPT, the results of which will be used to provide the volunteer with her pregnancy test result. During technician testing, the volunteer will complete the device usability and leaflet comprehension questionnaires.

At the end of the study visit, all volunteers will be provided with materials to allow follow-up for the determination of pregnancy status.

The majority of volunteers will be requested to provide one additional urine sample, collected 2 days after the study visit. If early pregnancy is suspected the volunteer will be requested to provide an additional 7 daily urine samples following the study visit. All volunteers will be required to provide details of pregnancy status (documented menses or pregnancy confirmation by health care professional) after the study visit.

True pregnancy status will be determined by laboratory tests and clinical information. The study will continue until a minimum of 300 pregnant and 300 not pregnant volunteers have completed the study.

Conditions

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Pregnancy

Keywords

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Pregnancy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Pregnancy test

Clearblue investigational Pregnancy test

Clearblue Marketed pregnancy test

Professional pregnancy test

Group Type OTHER

Clearblue Investigational Pregnancy test

Intervention Type OTHER

Clearblue Investigational Pregnancy test

Professional pregnancy test

Intervention Type OTHER

Alere Professional use pregnancy test

Clearblue Marketed Pregnancy test

Intervention Type OTHER

Clearblue Marketed Pregnancy test

Interventions

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Clearblue Investigational Pregnancy test

Clearblue Investigational Pregnancy test

Intervention Type OTHER

Professional pregnancy test

Alere Professional use pregnancy test

Intervention Type OTHER

Clearblue Marketed Pregnancy test

Clearblue Marketed Pregnancy test

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Female
* Aged 18 or over
* Willing to conduct a personal pregnancy test and reveal their pregnancy status
* Willing to give informed consent

Exclusion Criteria

* Currently or previously employed by SPD Development Company Ltd. (SPD), Alere, Unipath, Procter and Gamble (P\&G), or affiliates.
* Has an immediate relative\* currently or previously employed by SPD, Alere, Unipath or P\&G or affiliates
* Previously used the investigational HPT within the last six months
* Healthcare professionals (HCP's) with professional experience either using lateral flow based devices or conducting near patient testing
* Confirmed to be pregnant by a healthcare professional and beyond the first trimester
* Taken a hormonal preparation containing human chorionic gonadotropin (hCG) in the last month, e.g. Pregnyl®
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Illingworth Research Ltd

UNKNOWN

Sponsor Role collaborator

SPD Development Company Limited

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Juliet Hulse

Role: PRINCIPAL_INVESTIGATOR

Illingworth Research Ltd

Locations

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Illingworth Research Ltd

Macclesfield, Chester, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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PROTOCOL-0772

Identifier Type: -

Identifier Source: org_study_id