A Worldwide Antihistamine-Refractory Chronic Urticaria Patient Evaluation in Latin America and Canada (AWARE-LACan)

NCT ID: NCT02626221

Last Updated: 2018-12-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

497 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-12-24

Study Completion Date

2018-03-21

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This is a non-interventional, multi-country, Latin American study utilizing a prospective single-cohort design. Eligible CU patients will be enrolled in the study and will be followed for 24 months (± 6 weeks).

In accordance with the observational nature of the study, there will be no interventions or interference with the routine care of the patient which will be based solely on the clinical judgment of the treating physician. However, with respect to the frequency and schedule of assessments, the schedule included in Table 7-1 will be recommended.

The selection of the treatment for CU will be clearly separated from the decision to include the patient in the study, and will be made at the discretion of the treating physician in accordance with standard medical practice, the investigator's clinical judgment, and global urticarial guidelines.

In order to prevent selection bias, investigators should offer enrollment to all consecutive patients meeting study criteria, likely to be available for the full duration of the follow-up period of 24 months, and willing to participate in the study.

The overall objective of the study is to evaluate in real-life the CU disease burden, the current treatment patterns and the use of health care resources in patients refractory to H1-antihistamine treatment

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Chronic Urticaria

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Single

Single Cohort Study

Non Interventional Study

Intervention Type OTHER

Non Interventional Study

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Non Interventional Study

Non Interventional Study

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

Men or Women at least 18 years of age or older. Patient has medically confirmed diagnosis of chronic urticaria present for more than 2 months.

Patient has been treated with at least one course of H1 antihistamines and is refractory to this treatment Patient has provided written informed consent allowing the use of their anonymous data for the purposes of the study

Exclusion Criteria

Patient is currently participating in a clinical trial. Patient is, in the opinion of the treating physician, unlikely to be available for the full duration of the follow-up period of 24 months
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Novartis Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Novartis Investigative Site

CABA, Buenos Aires, Argentina

Site Status

Novartis Investigative Site

Ciudad Autonoma de Bs As, Buenos Aires, Argentina

Site Status

Novartis Investigative Site

Ciudad Autonoma de Bs As, Buenos Aires, Argentina

Site Status

Novartis Investigative Site

Lobos, Buenos Aires, Argentina

Site Status

Novartis Investigative Site

Buenos Aires, Nueve De Julio, Argentina

Site Status

Novartis Investigative Site

Rosario, Santa Fe Province, Argentina

Site Status

Novartis Investigative Site

Rosario, Santa Fe Province, Argentina

Site Status

Novartis Investigative Site

Buenos Aires, , Argentina

Site Status

Novartis Investigative Site

Mendoza, , Argentina

Site Status

Novartis Investigative Site

Salta, , Argentina

Site Status

Novartis Investigative Site

Rio de Janeiro, Rio de Janeiro, Brazil

Site Status

Novartis Investigative Site

Alphaville / Barueri, São Paulo, Brazil

Site Status

Novartis Investigative Site

Guarulhos, São Paulo, Brazil

Site Status

Novartis Investigative Site

Santo André, São Paulo, Brazil

Site Status

Novartis Investigative Site

São Paulo, São Paulo, Brazil

Site Status

Novartis Investigative Site

Medellín, Antioquia, Colombia

Site Status

Novartis Investigative Site

Barranquilla, Atlántico, Colombia

Site Status

Novartis Investigative Site

Bogotá, Cundinamarca, Colombia

Site Status

Novartis Investigative Site

Medellín, , Colombia

Site Status

Novartis Investigative Site

San José, , Costa Rica

Site Status

Novartis Investigative Site

San Rafael Escazu, , Costa Rica

Site Status

Novartis Investigative Site

Santiago de los Caballeros, Republica Dominicana, Dominican Republic

Site Status

Novartis Investigative Site

Santo Domingo, Republica Dominicana, Dominican Republic

Site Status

Novartis Investigative Site

Santo Domingo, , Dominican Republic

Site Status

Novartis Investigative Site

Guatemala City, , Guatemala

Site Status

Novartis Investigative Site

San Pedro Sula, , Honduras

Site Status

Novartis Investigative Site

San Pedro Sula, , Honduras

Site Status

Novartis Investigative Site

Tegucigalpa, , Honduras

Site Status

Novartis Investigative Site

Panama City, , Panama

Site Status

Novartis Investigative Site

Jesus Maria, Lima region, Peru

Site Status

Novartis Investigative Site

San Martín de Porres, Lima region, Peru

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Argentina Brazil Colombia Costa Rica Dominican Republic Guatemala Honduras Panama Peru

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CIGE025EVE01

Identifier Type: -

Identifier Source: org_study_id