The Safety and Effect Study of Acupuncture for Anorexia in Patients With Gastrointestinal Tract and Lung Cancers
NCT ID: NCT02619266
Last Updated: 2015-12-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
PHASE2/PHASE3
160 participants
INTERVENTIONAL
2015-12-31
2017-02-28
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Acupuncture+Placebo
Acupuncture once daily for 7 days and Placebo tablet by mouth, twice a day for 7 days.
Acupuncture
Acupuncture is the practice of inserting thin needles into specific points to improve health and well-being.
Placebo(Megestrol Acetate)
Starch pill manufactured to mimic Megestrol Acetate 160mg tablet
Megestrol Acetate+Sham acupuncture
Megestrol Acetate tablet 160mg by mouth, twice a day for 7 days and Sham Acupuncture once a day for 7 days .
Sham Acupuncture
Sham acupuncture is used as a control in scientific studies that test the efficacy of acupuncture in the treatment of various illness or disorders.
Megestrol Acetate
Megestrol Acetate 160mg tablet
Placebo+Sham acupuncture
Placebo tablet by mouth, twice a day for 7 days and Sham Acupuncture once a day for 7 days .
Sham Acupuncture
Sham acupuncture is used as a control in scientific studies that test the efficacy of acupuncture in the treatment of various illness or disorders.
Placebo(Megestrol Acetate)
Starch pill manufactured to mimic Megestrol Acetate 160mg tablet
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Acupuncture
Acupuncture is the practice of inserting thin needles into specific points to improve health and well-being.
Sham Acupuncture
Sham acupuncture is used as a control in scientific studies that test the efficacy of acupuncture in the treatment of various illness or disorders.
Megestrol Acetate
Megestrol Acetate 160mg tablet
Placebo(Megestrol Acetate)
Starch pill manufactured to mimic Megestrol Acetate 160mg tablet
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
2. Age ≥18 years;
3. Appetite score≤ 6 (0= worst appetite), and the symptom lasted 2 weeks at lest at screening;
4. Had a history of weight loss ≥5% within 6 moths;
5. Maintained oral intake;
6. Signed the informed consent.
Exclusion Criteria
2. Had uncontrolled symptoms that could impact appetite or caloric intake such as nausea, pain, or depression(The score of the symptoms≤ 3, 0= worst) ;
3. Patients with untreated vitamin B12 deficiency or endocrine abnormalities(thyroid dysfunction and hypoadrenalism);
4. Patients on melatonin supplements or medications with potential appetite-stimulating activity(Chinese herb,thalidomide)
5. Less than one week before the screening or there will be a surgery ,radiotherapy and chemotherapy the acupuncture;
6. Lifetime expected less than 3 months.
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Chengdu University of Traditional Chinese Medicine
OTHER
Xinqiao Hospital of Chongqing
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Chaoting Zhao
Vice Director, Clinical Reseach
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Yong Tang, PhD
Role: STUDY_CHAIR
Chengdu University of Traditional Chinese Medicine
Chaoting Zhao, MD
Role: STUDY_DIRECTOR
Xinqiao Hospital
Haiou Luo, PhD
Role: PRINCIPAL_INVESTIGATOR
Xinqiao Hospital
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Chongqing TCM Hospital
Jiangbei, Chongqing Municipality, China
XinQiao Hosiptal
Shapingba, Chongqing Municipality, China
Donghua Hosiptal
Shapingba, Chongqing Municipality, China
Daping Hospital
Yuzhong, Chongqing Municipality, China
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Jian Li, MD
Role: primary
Dong Li, MD
Role: primary
References
Explore related publications, articles, or registry entries linked to this study.
Del Fabbro E, Dev R, Hui D, Palmer L, Bruera E. Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial. J Clin Oncol. 2013 Apr 1;31(10):1271-6. doi: 10.1200/JCO.2012.43.6766. Epub 2013 Feb 25.
Bruera E, Strasser F, Palmer JL, Willey J, Calder K, Amyotte G, Baracos V. Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: a double-blind, placebo-controlled study. J Clin Oncol. 2003 Jan 1;21(1):129-34. doi: 10.1200/JCO.2003.01.101.
Bruera E, Macmillan K, Kuehn N, Hanson J, MacDonald RN. A controlled trial of megestrol acetate on appetite, caloric intake, nutritional status, and other symptoms in patients with advanced cancer. Cancer. 1990 Sep 15;66(6):1279-82. doi: 10.1002/1097-0142(19900915)66:63.0.co;2-r.
Related Links
Access external resources that provide additional context or updates about the study.
Acupuncture for Unintentional Weight Loss and Anorexia With GI Cancer
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2015CB554504
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
2014YLC32
Identifier Type: -
Identifier Source: org_study_id