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Effects of Standing and Light-intensity Activity on Ambulatory Blood Pressure and Blood Glucose

NCT ID: NCT02616809

Last Updated: 2015-11-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-07-31

Study Completion Date

2015-04-30

Brief Summary

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This study aims to test the short-term effects of intermittent standing, slow cycling and slow walking, compared to sitting, on continuous blood glucose and ambulatory blood pressure among pre-hypertensive and pre-diabetic adults.

Detailed Description

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This study will enroll 10 adults who will each complete four experimental conditions in random order. Each of the four experimental conditions are as follows: 1) sit continuously for 8 hours in a simulated office environment, 2) break-up sitting time with standing based on set hourly intervals, 3) break-up sitting time with slow-walking on a treadmill desk based on set hourly intervals, 4) increase energy expenditure by slow cycling based on set hourly intervals. Participants will completed each condition one week apart and dietary intake will be standardized by giving participants the same meals during each intervention condition. Study measures will include: anthropometrics (height and weight), blood pressure, fasting glucose, 24-continuous glucose monitoring, full-day ambulatory blood pressure monitoring, cognitive testing (cognitive performance), energy expenditure, physical activity via accelerometer, sleep via accelerometer, and heart rate.

Conditions

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Diabetes Hypertension Sleep

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Sitting

Participants will sit continuously for 8 hours in a simulated office environment

Group Type EXPERIMENTAL

Maintaining posture and energy expenditure

Intervention Type OTHER

Participants will sit continuously for 8-hrs during a simulated office environment

slow cycling

Participants will cycle at regular hourly intervals during an 8-hr simulated office environment

Group Type EXPERIMENTAL

Increasing energy expenditure

Intervention Type OTHER

Participants will cycle slowly while seated in prescribed hourly intervals. This condition will increase energy expenditure while keeping a sitting posture

standing

Participants will change posture (from sitting to standing) during hourly intervals for an 8-hr period in a simulated office environment

Group Type EXPERIMENTAL

Changing posture

Intervention Type OTHER

Participants will transition from sitting to standing in prescribed hourly intervals. This condition will change posture (sit to stand) while maintaining low energy expenditure

slow walking

Participants will transition from sitting to slow walking on a treadmill desk at regular hourly intervals during an 8-hr period in a simulated office environment

Group Type EXPERIMENTAL

Increasing energy expenditure and changing posture

Intervention Type OTHER

Participants will transition from sitting to a walking workstation in prescribed hourly intervals. This condition will both increase energy expenditure and change posture.

Interventions

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Maintaining posture and energy expenditure

Participants will sit continuously for 8-hrs during a simulated office environment

Intervention Type OTHER

Increasing energy expenditure

Participants will cycle slowly while seated in prescribed hourly intervals. This condition will increase energy expenditure while keeping a sitting posture

Intervention Type OTHER

Changing posture

Participants will transition from sitting to standing in prescribed hourly intervals. This condition will change posture (sit to stand) while maintaining low energy expenditure

Intervention Type OTHER

Increasing energy expenditure and changing posture

Participants will transition from sitting to a walking workstation in prescribed hourly intervals. This condition will both increase energy expenditure and change posture.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* pre-hypertensive (systolic blood pressure 120-139 mmHg, or diastolic blood pressure 80-89 mmHg)
* impaired fasting glucose (5.6-6.9 mmil/L)
* not meeting the physical activity guidelines for adults (\>=150 min/wk of moderate-to-vigorous physical activity)

Exclusion Criteria

* smoking, pregnancy, known coronary heart disease, orthopedic limitations for performing physical activity, taking medications to control high blood pressure or high blood glucose, special dietary requirements, and being advised by a doctor to avoid prolonged periods of sitting.
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Arizona State University

OTHER

Sponsor Role lead

Responsible Party

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Noe Crespo

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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1306009298

Identifier Type: -

Identifier Source: org_study_id