The Safety, Efficacy and Tolerability of Remote Ischemic Preconditioning as a Therapy to DMD
NCT ID: NCT02614820
Last Updated: 2015-11-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
100 participants
INTERVENTIONAL
2015-11-30
2016-12-31
Brief Summary
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Methods: 100 patients (aged 2 to 6 years)will be divided into two groups(treatment and control groups) randomly. Treatment group will receive an RIPC stimulus (inflation of a blood pressure cuff on the bilateral thighs to 150 mm Hg for four 5-minute intervals) while control group will receive a similar stimulus (inflation of a blood pressure cuff on the bilateral thighs to 40 mm Hg for four 5-minute intervals). Serum kinase level ,Blood levels of myoglobin, Evaluation of motor function(Four steps test;6-minute walking test) and MRI of lower limbs）at 0 days, 3 days, 3months ,6months.
Purpose：
1. To evaluate the safety and tolerability of remote ischemic preconditioning for DMD patients
2. To identify the effectiveness of remote ischemic preconditioning for DMD patients.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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treatment group
inflation of a blood pressure cuff on the bilateral thighs to 150 mm Hg for four 5-minute intervals
Remote Ischemic Preconditioning Training Apparatus
control group
inflation of a blood pressure cuff on the bilateral thighs to 40 mm Hg for four 5-minute intervals
Remote Ischemic Preconditioning Training Apparatus
Interventions
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Remote Ischemic Preconditioning Training Apparatus
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
2 Years
6 Years
MALE
No
Sponsors
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General Hospital of Chinese Armed Police Forces
OTHER
Responsible Party
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Locations
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Shiwen wu
Beijing, , China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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JZheng
Identifier Type: -
Identifier Source: org_study_id