The Balance Control Mechanism of DPN Patients

NCT ID: NCT02606747

Last Updated: 2015-11-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-03-31

Study Completion Date

2016-06-30

Brief Summary

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This study will evaluate the balance ability of DPN (diabetic peripheral neuropathy)patients, which will help us to understand the relationship between peripheral and central nervous system, in order to early diagnosis and prevent the fall in DPN patients.

Detailed Description

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DPN is one of the most common complications of diabetes. The clinical manifestation of DPN contains sensory reduction, pain, muscle wastage and so on. Sensory and motor nervous are one of the most important factors in balance control, the reduction of balance ability will result in high risk of fall.

Most studies about DPN are focus on peripheral nervous, however, the central nervous system may also be involved in DPN patients. In this study, force platform, proprioception test and fMRI will be used to evaluate balance ability, proprioception and the brain function information of DPN patients, which will help to understand the relationship between peripheral and central nervous system.

Conditions

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Diabetic Neuropathy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Diabetes mellitus with DPN

Aged from 40 to 80. Normal cognitive ability. Right handed. Able to walk without any other kinds of central nervous system disorder. Confirmed diabetes with DPN.

Intervention Type OTHER

routine blood sugar control

Diabetes mellitus without DPN

Aged from 40 to 80. Normal cognitive ability. Right handed. Able to walk without any other kinds of central nervous system disorder. Confirmed diabetes without DPN.

Intervention Type OTHER

routine blood sugar control

Interventions

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routine blood sugar control

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* diabetics
* normal cognitive ability
* walk normally
* normal vision

Exclusion Criteria

* other nervous system disease, foot ulcer
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Geheng Yuan

OTHER

Sponsor Role lead

Responsible Party

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Geheng Yuan

Peking University first hospital

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Jue Zhang, Ph. D

Role: STUDY_CHAIR

PKU

Locations

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Peking University First Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Ye Wang, Ph. D

Role: CONTACT

+8613718946837

Facility Contacts

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Geheng Yuan, M.D

Role: primary

+8613811235488

Other Identifiers

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11372013

Identifier Type: -

Identifier Source: org_study_id