Diversion-p64 Post Market Clinical Follow-Up Study to Assess Safety and Effectiveness of the p64 Flow Modulation Device

NCT ID: NCT02600364

Last Updated: 2020-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

450 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-12-31

Study Completion Date

2020-06-30

Brief Summary

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The purpose of this study is to assess safety and effectiveness of the p64 Flow Modulation Device.

Detailed Description

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Title: Diversion-p64. Device: p64 Flow Modulation Device. Study design: Prospective, multicenter, single arm Post Market Clinical Follow-Up Study.

Purpose: To assess safety and effectiveness of p64. Study duration: 48 months. Sample Size: 400 patients. Number of sites: \> 20. Follow-up intervals: Two independent follow-ups (after 3-6 and 7-12 months) according to site specific standard.

Conditions

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Intracranial Aneurysm

Keywords

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Aneurysm intracerebral stroke p64

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Age ≥ 18
2. Patient harbours either one saccular or one dissecting or one blisterlike or one fusiform intracerebral aneurysm or one intracerebral segmental disease, in the anterior circulation for which the indication for p64 treatment is given
3. Patient or legal representative provides written informed consent verifying that he/she consents to the use of his/her data (according to the data protection laws)

Exclusion Criteria

1. Aneurysms of the posterior circulation
2. Imaging evidence of bifurcation aneurysms
3. Imaging evidence of dissections
4. Imaging evidence of fistulae
5. Imaging evidence of arteriovenous malformations
6. Patient is harbouring another aneurysm that has to be treated within six months after first procedure
7. Known allergy to study medication, e.g. ASA, Clopidogrel, Heparin or contrast media
8. Confirmation of positive pregnancy test according to site specific standard of care (e.g. test, verbal communication)
9. Current involvement in another study or trial
10. Parent vessel treated with other Flow Diverters than p64 during intervention and re-treatment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Phenox GmbH

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alain Bonafé, Prof. Dr.

Role: PRINCIPAL_INVESTIGATOR

Hôpital Gui de Chauliac (CHU de Montpellier), Montpellier, France

Locations

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Clínica La Sagrada Familia

Buenos Aires, , Argentina

Site Status

Ziekenhuis Oost-Limburg

Genk, , Belgium

Site Status

St. Ivan Rilski Hospital

Sofia, , Bulgaria

Site Status

Groupe Hospitalier Pellegrin

Bordeaux, , France

Site Status

Hôpital Pierre Wertheimer

Bron, , France

Site Status

Hôpital Bicêtre

Le Kremlin-Bicêtre, , France

Site Status

Hôpital Gui de Chauliac (CHU Montpellier)

Montpellier, , France

Site Status

Hôpital Pitié Salpétrière

Paris, , France

Site Status

CHRU Hôpital Maison-Blanche

Reims, , France

Site Status

Hôpital Bretonneau (CHRU de Tours)

Tours, , France

Site Status

Klinikum Augsburg

Augsburg, , Germany

Site Status

Klinikum Bremen-Mitte

Bremen, , Germany

Site Status

HELIOS Klinikum Erfurt

Erfurt, , Germany

Site Status

Knappschaftskrankenhaus Recklinghausen

Recklinghausen, , Germany

Site Status

Universitätsklinikum Regensburg

Regensburg, , Germany

Site Status

Klinikum Stuttgart Katharinenhospital

Stuttgart, , Germany

Site Status

Ospedale Bellaria Carlo Alberto Pizzardi

Bologna, , Italy

Site Status

IRCCS Istituto Clinico Humanitas

Rozzano, , Italy

Site Status

Regionalny Szpital Specjalistyczny

Grudziądz, , Poland

Site Status

Uniwersytecki Szpital Kliniczny we Wroclawiu

Wroclaw, , Poland

Site Status

Life Memorial Hospital

Bucharest, , Romania

Site Status

NSI Burdenko, Moscow

Moscow, , Russia

Site Status

Federal Almazov North-West Medical Research Centre

Saint Petersburg, , Russia

Site Status

Western General Hospital

Edinburgh, , United Kingdom

Site Status

Leeds Teaching Hospitals NHS TRUST

Leeds, , United Kingdom

Site Status

St George's Hospital

London, , United Kingdom

Site Status

Countries

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Hungary Slovakia Spain Argentina Belgium Bulgaria France Germany Italy Poland Romania Russia United Kingdom

Related Links

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http://phenox.net/

www.phenox.net

Other Identifiers

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DP64/BO1507

Identifier Type: -

Identifier Source: org_study_id