Evolution of the PR Interval in Patients Implanted With a Pacemaker Using the SafeR Mode

NCT ID: NCT02586480

Last Updated: 2017-10-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

848 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-04-30

Study Completion Date

2015-12-31

Brief Summary

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Observational study on long PR interval using the SafeR mode in bradycardia patients.

Detailed Description

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This observational trial aims to study the evolution of the PR interval in patients implanted with a dual chamber pacemaker with the SafeR mode. The investigators will assess the prevalence and the incidence of PR lengthening and the investigators will study the long PR interval management by physicians, depending on the data embedded in the pacemaker.

Conditions

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Sinus Node Dysfunction Atrioventricular Block

Keywords

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bradycardia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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dual chamber pacemaker with SafeR algorithm

SafeR is an AVB management algorithm: it provides AAI pacing while continuously monitoring AV conduction, it switches to DDD when detecting AVB I, II or III, according to the following criteria: (1) AVB I: 6 long PR intervals, (2) AVB II: 3 blocked atrial events/12 cycles, (3) AVB III: 2 consecutive blocked atrial events. It switches back to AAI mode when needed.

Intervention Type DEVICE

Other Intervention Names

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Reply DR (Sorin Devices)

Eligibility Criteria

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Inclusion Criteria

* Patient implanted (primo-implant, replacement, upgrade) with a Sorin Group™ dual chamber pacemaker according to current available guidelines and IFU from less than three months.
* Since implantation, the device is programmed in SafeR mode
* Patient agreed to participate, after having received the appropriate and mandatory information

Exclusion Criteria

* Patient contraindicated for cardiac pacing, according to current available guidelines
* Permanent atrial fibrillation
* Permanent high-degree AV block
* Patient not available for routine follow-up visits
* Patient already included in another clinical study
* Inability to understand the purpose of the study / refusal to cooperate
* minor age
* Pregnancy
* Life expectancy less than 12 months
* Under guardianship
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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LivaNova

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jérôme TAIEB, MD

Role: PRINCIPAL_INVESTIGATOR

CH du Pays d'Aix - Aix en Provence

Locations

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CH Basse Terre

Terre Basse, Guadeloupe, France

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CH du Pays d'Aix

Aix-en-Provence, , France

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CH Alençon

Alençon, , France

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Cabinet Alès

Alès, , France

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hôpital Sud

Amiens, , France

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CH Annecy

Annecy, , France

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hôpital privé Antony

Antony, , France

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hôpital d'Argenteuil

Argenteuil, , France

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hôpital St André

Bordeaux, , France

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CH Bourges

Bourges, , France

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CHU Brest

Brest, , France

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Clinique Keraudren

Brest, , France

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CHU Caen

Caen, , France

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Clinique des 2 Caps

Calais, , France

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CH Chartres

Chartres, , France

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Ch Chaumont

Chaumont, , France

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Cabinet Cherbourg

Cherbourg, , France

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HIA Percy

Clamart, , France

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Hôpital L. Pasteur

Colmar, , France

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CH Corbeil Essonnes

Corbeil-Essonnes, , France

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Cabinet Creutzwald

Creutzwald, , France

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Hopital Henri Mondor

Créteil, , France

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CH Dinan

Dinan, , France

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CH Douarnenez

Douarnenez, , France

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CH Evreux

Évreux, , France

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CMCO Evry

Évry, , France

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Cabinet Forbach

Forbach, , France

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CH Forbach

Forbach, , France

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CH Haguenau

Haguenau, , France

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CH Helfaut

Helfaut, , France

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CH Lannion

Lannion, , France

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CH Le Havre

Le Havre, , France

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CMCM Le Mans

Le Mans, , France

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CMC Port Marly

Le Port-Marly, , France

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CH Lomme

Lomme, , France

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CH Lorient

Lorient, , France

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CHU La Timone

Marseille, , France

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Hôpital Nord

Marseille, , France

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Clinique Melun

Melun, , France

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CH Privé Metz

Metz, , France

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CH Montfermeil

Montfermeil, , France

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Clinique Montpellier

Montpellier, , France

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Clinique A. Paré

Nancy, , France

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NCN Nantes

Nantes, , France

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CH Orléans

Orléans, , France

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Cabinet Paris

Paris, , France

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CH St Joseph

Paris, , France

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CH Poissy St Germain

Poissy, , France

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CHU Poitiers

Poitiers, , France

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Clinique St Hilaire

Rouen, , France

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CCN St Denis

Saint-Denis, , France

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CH St Nazaire

Saint-Nazaire, , France

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CH Sens

Sens, , France

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CH St Malo

St-Malo, , France

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CH Thionville

Thionville, , France

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CH Valenciennes

Valenciennes, , France

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Cabinet Valognes

Valognes, , France

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CH Villefrance

Villefranche-sur-Saône, , France

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Countries

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France

Other Identifiers

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RBSY02

Identifier Type: -

Identifier Source: org_study_id