Trial Outcomes & Findings for Trial Evaluating Postop Pain and Muscle Strength Among Regional Anesthesia Techniques for Ambulatory ACL Reconstruction (NCT NCT02584452)
NCT ID: NCT02584452
Last Updated: 2019-12-11
Results Overview
Subjective subjective postoperative pain scores at POD 2 of preoperative femoral nerve block plus postoperative continuous adductor canal nerve catheter compared to preoperative femoral nerve block plus postoperative saphenous nerve block at 48 hours after discharge from PACU using Subjective Numeric Pain Scale score (on an 11 point scale when 0 is no pain and 10 is worst pain).
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
59 participants
Primary outcome timeframe
Post Operative Day 2
Results posted on
2019-12-11
Participant Flow
Two participants consented but withdrew from the study prior to randomization.
Participant milestones
| Measure |
Continuous Adductor Canal Nerve Catheter
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Patients then undergo general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction with propofol bolus and placement of laryngeal mask airway. Intraoperative opioid limited to no \> 150mcg of fentanyl. Completion of procedure, dressing and LMA revoved with patients transferred to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
|
Long Acting Single Bolus Adductor Canal Nerve Block
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Patients then undergo general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no \> 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc.
|
|---|---|---|
|
Overall Study
STARTED
|
34
|
23
|
|
Overall Study
COMPLETED
|
32
|
21
|
|
Overall Study
NOT COMPLETED
|
2
|
2
|
Reasons for withdrawal
| Measure |
Continuous Adductor Canal Nerve Catheter
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Patients then undergo general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction with propofol bolus and placement of laryngeal mask airway. Intraoperative opioid limited to no \> 150mcg of fentanyl. Completion of procedure, dressing and LMA revoved with patients transferred to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
|
Long Acting Single Bolus Adductor Canal Nerve Block
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Patients then undergo general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no \> 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc.
|
|---|---|---|
|
Overall Study
Physician Decision
|
1
|
1
|
|
Overall Study
Lost to Follow-up
|
1
|
1
|
Baseline Characteristics
Race and Ethnicity were not collected from any participant.
Baseline characteristics by cohort
| Measure |
Continuous Adductor Canal Nerve Catheter
n=32 Participants
Ultrasound guided femoral nerve block with 20cc 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long Acting Single Bolus Adductor Canal Nerve Block
n=21 Participants
Ultrasound guided femoral nerve block with 20cc 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
Total
n=53 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Categorical
<=18 years
|
12 Participants
n=32 Participants
|
9 Participants
n=21 Participants
|
21 Participants
n=53 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
20 Participants
n=32 Participants
|
12 Participants
n=21 Participants
|
32 Participants
n=53 Participants
|
|
Age, Categorical
>=65 years
|
0 Participants
n=32 Participants
|
0 Participants
n=21 Participants
|
0 Participants
n=53 Participants
|
|
Sex: Female, Male
Female
|
14 Participants
n=32 Participants
|
5 Participants
n=21 Participants
|
19 Participants
n=53 Participants
|
|
Sex: Female, Male
Male
|
18 Participants
n=32 Participants
|
16 Participants
n=21 Participants
|
34 Participants
n=53 Participants
|
|
Race and Ethnicity Not Collected
|
—
|
—
|
0 Participants
Race and Ethnicity were not collected from any participant.
|
|
Region of Enrollment
United States
|
32 participants
n=32 Participants
|
21 participants
n=21 Participants
|
53 participants
n=53 Participants
|
PRIMARY outcome
Timeframe: Post Operative Day 2Population: Data was unavailable for 1 participant in the Long Acting Single Bolus Adductor Canal Nerve Block group.
Subjective subjective postoperative pain scores at POD 2 of preoperative femoral nerve block plus postoperative continuous adductor canal nerve catheter compared to preoperative femoral nerve block plus postoperative saphenous nerve block at 48 hours after discharge from PACU using Subjective Numeric Pain Scale score (on an 11 point scale when 0 is no pain and 10 is worst pain).
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=32 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=20 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Subjective Postoperative Pain Scores After Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postop Saphenous Nerve Block at 48 Hours After Discharge From PACU.
0 (Pain on Subjective Numeric Pain Scale)
|
1 Participants
|
1 Participants
|
|
Subjective Postoperative Pain Scores After Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postop Saphenous Nerve Block at 48 Hours After Discharge From PACU.
1 (Pain on Subjective Numeric Pain Scale)
|
2 Participants
|
0 Participants
|
|
Subjective Postoperative Pain Scores After Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postop Saphenous Nerve Block at 48 Hours After Discharge From PACU.
2 (Pain on Subjective Numeric Pain Scale)
|
6 Participants
|
3 Participants
|
|
Subjective Postoperative Pain Scores After Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postop Saphenous Nerve Block at 48 Hours After Discharge From PACU.
3 (Pain on Subjective Numeric Pain Scale)
|
7 Participants
|
4 Participants
|
|
Subjective Postoperative Pain Scores After Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postop Saphenous Nerve Block at 48 Hours After Discharge From PACU.
4 (Pain on Subjective Numeric Pain Scale)
|
5 Participants
|
4 Participants
|
|
Subjective Postoperative Pain Scores After Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postop Saphenous Nerve Block at 48 Hours After Discharge From PACU.
5 (Pain on Subjective Numeric Pain Scale)
|
5 Participants
|
1 Participants
|
|
Subjective Postoperative Pain Scores After Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postop Saphenous Nerve Block at 48 Hours After Discharge From PACU.
6 (Pain on Subjective Numeric Pain Scale)
|
3 Participants
|
2 Participants
|
|
Subjective Postoperative Pain Scores After Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postop Saphenous Nerve Block at 48 Hours After Discharge From PACU.
7 (Pain on Subjective Numeric Pain Scale)
|
2 Participants
|
2 Participants
|
|
Subjective Postoperative Pain Scores After Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postop Saphenous Nerve Block at 48 Hours After Discharge From PACU.
8 (Pain on Subjective Numeric Pain Scale)
|
0 Participants
|
3 Participants
|
|
Subjective Postoperative Pain Scores After Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postop Saphenous Nerve Block at 48 Hours After Discharge From PACU.
9 (Pain on Subjective Numeric Pain Scale)
|
1 Participants
|
0 Participants
|
PRIMARY outcome
Timeframe: Post Operative Day 1Population: Data was unavailable for 1 participant in both groups.
Quadriceps strength on POD 1 of preoperative femoral nerve block plus postoperative continuous adductor canal nerve catheter compared to preoperative femoral nerve block plus postoperative saphenous nerve block using Straight Leg Raise Tests, 0-5/5 scale, and knee extension, 0-5/5 scale. On both scales (straight leg raise test and knee extension) 0 indicates the minimum value (low muscle contraction/no movement) and 5 indicates the maximum (normal muscle contraction /pt holds position against pressure).
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=31 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=20 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Straight Leg Raise Test · 0
|
1 Participants
|
2 Participants
|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Straight Leg Raise Test · 1
|
3 Participants
|
7 Participants
|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Straight Leg Raise Test · 4
|
8 Participants
|
4 Participants
|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Straight Leg Raise Test · 5
|
2 Participants
|
1 Participants
|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Knee extension Test · 0
|
2 Participants
|
2 Participants
|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Knee extension Test · 1
|
2 Participants
|
3 Participants
|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Knee extension Test · 2
|
11 Participants
|
9 Participants
|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Knee extension Test · 3
|
9 Participants
|
3 Participants
|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Knee extension Test · 4
|
6 Participants
|
2 Participants
|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Knee extension Test · 5
|
1 Participants
|
1 Participants
|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Straight Leg Raise Test · 2
|
9 Participants
|
4 Participants
|
|
Quadriceps Strength of on POD 1 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block at 48 Hours After Discharge From PACU
Straight Leg Raise Test · 3
|
8 Participants
|
2 Participants
|
SECONDARY outcome
Timeframe: Post Operative Day 1Subjective pain scores on POD 1 of patients receiving (1) preoperative femoral nerve block plus postoperative continuous adductor canal nerve catheter compared to (2) preoperative femoral nerve block plus postoperative saphenous nerve block using Subjective Numeric Pain Scale score (on an 11 point scale when 0 is no pain and 10 is worst pain).
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=32 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=21 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Subjective Pain Scores on POD 1 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
0 (Pain on Subjective Numeric Pain Scale)
|
1 Participants
|
0 Participants
|
|
Subjective Pain Scores on POD 1 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
1 (Pain on Subjective Numeric Pain Scale)
|
2 Participants
|
1 Participants
|
|
Subjective Pain Scores on POD 1 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
2 (Pain on Subjective Numeric Pain Scale)
|
3 Participants
|
1 Participants
|
|
Subjective Pain Scores on POD 1 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
3 (Pain on Subjective Numeric Pain Scale)
|
11 Participants
|
5 Participants
|
|
Subjective Pain Scores on POD 1 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
4 (Pain on Subjective Numeric Pain Scale)
|
3 Participants
|
2 Participants
|
|
Subjective Pain Scores on POD 1 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
5 (Pain on Subjective Numeric Pain Scale)
|
5 Participants
|
2 Participants
|
|
Subjective Pain Scores on POD 1 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
6 (Pain on Subjective Numeric Pain Scale)
|
4 Participants
|
4 Participants
|
|
Subjective Pain Scores on POD 1 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
7 (Pain on Subjective Numeric Pain Scale)
|
2 Participants
|
1 Participants
|
|
Subjective Pain Scores on POD 1 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
7.5 (Pain on Subjective Numeric Pain Scale)
|
0 Participants
|
1 Participants
|
|
Subjective Pain Scores on POD 1 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
8 (Pain on Subjective Numeric Pain Scale)
|
1 Participants
|
4 Participants
|
SECONDARY outcome
Timeframe: Post Operative Day 2 and 3Population: Data was unavailable for 1 participant in the Long Acting Single Bolus Adductor Canal Nerve Block group on post operative days 2 and 3.
Total postop opioid consumption measured by total pain pills on POD 2 and 3 of patients receiving (1) preoperative femoral nerve block plus postoperative continuous adductor canal nerve catheter compared to (2) preoperative femoral nerve block plus postoperative saphenous nerve block.
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=32 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=20 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 0 pills
|
3 Participants
|
0 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 1 pill
|
0 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 2 pills
|
2 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 3 pills
|
1 Participants
|
2 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 4 pills
|
6 Participants
|
3 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 4.5 pills
|
0 Participants
|
0 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 5 pills
|
9 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 6 pills
|
2 Participants
|
5 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 7 pills
|
2 Participants
|
0 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 8 pills
|
6 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 9 pills
|
0 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 10 pills
|
1 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 11 pills
|
0 Participants
|
2 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 12 pills
|
0 Participants
|
2 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 2 · 13 pills
|
0 Participants
|
0 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 0 pills
|
3 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 1 pill
|
1 Participants
|
0 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 2 pills
|
3 Participants
|
2 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 3 pills
|
3 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 4 pills
|
6 Participants
|
2 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 4.5 pills
|
0 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 5 pills
|
4 Participants
|
4 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 6 pills
|
7 Participants
|
2 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 8 pills
|
1 Participants
|
2 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 7 pills
|
2 Participants
|
0 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 9 pills
|
1 Participants
|
0 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 10 pills
|
1 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 11 pills
|
0 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 12 pills
|
0 Participants
|
2 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
Post Operative Day 3 · 13 pills
|
0 Participants
|
1 Participants
|
SECONDARY outcome
Timeframe: Post Operative Week 6Population: Data was unavailable for 1 participant in each group.
Quadriceps strength on POD week 6- pts receiving (1) long-acting single bolus adductor canal nerve block comparied to (2) continuous adductor canal nerve catheter using Straight Leg Raise Tests, 0-5/5 scale, and knee extension, 0-5/5 scale. On both scales (straight leg raise test and knee extension) 0 indicates the minimum value (low muscle contraction/no movement) and 5 indicates the maximum (normal muscle contraction /pt holds position against pressure).
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=31 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=20 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Quadriceps Strength on POD Week 6- Pts Receiving (1) Long-acting Single Bolus Adductor Canal Nerve Block Comparied to (2) Continuous Adductor Canal Nerve Catheter.
Straight Leg Raise Test · 5
|
15 Participants
|
10 Participants
|
|
Quadriceps Strength on POD Week 6- Pts Receiving (1) Long-acting Single Bolus Adductor Canal Nerve Block Comparied to (2) Continuous Adductor Canal Nerve Catheter.
Straight Leg Raise Test · 3
|
1 Participants
|
1 Participants
|
|
Quadriceps Strength on POD Week 6- Pts Receiving (1) Long-acting Single Bolus Adductor Canal Nerve Block Comparied to (2) Continuous Adductor Canal Nerve Catheter.
Straight Leg Raise Test · 4
|
15 Participants
|
9 Participants
|
|
Quadriceps Strength on POD Week 6- Pts Receiving (1) Long-acting Single Bolus Adductor Canal Nerve Block Comparied to (2) Continuous Adductor Canal Nerve Catheter.
Knee extension Test · 3
|
3 Participants
|
3 Participants
|
|
Quadriceps Strength on POD Week 6- Pts Receiving (1) Long-acting Single Bolus Adductor Canal Nerve Block Comparied to (2) Continuous Adductor Canal Nerve Catheter.
Knee extension Test · 4
|
21 Participants
|
12 Participants
|
|
Quadriceps Strength on POD Week 6- Pts Receiving (1) Long-acting Single Bolus Adductor Canal Nerve Block Comparied to (2) Continuous Adductor Canal Nerve Catheter.
Knee extension Test · 5
|
7 Participants
|
5 Participants
|
SECONDARY outcome
Timeframe: Post Operative Day 1Population: Data was unavailable for 1 participant in both groups.
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=31 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=20 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Physical Therapy Participation With a Subjective Assessment of Participant Ability to Participate in PT (Full, Partial, None)
Full participation
|
27 Participants
|
15 Participants
|
|
Physical Therapy Participation With a Subjective Assessment of Participant Ability to Participate in PT (Full, Partial, None)
Partial participation
|
4 Participants
|
4 Participants
|
|
Physical Therapy Participation With a Subjective Assessment of Participant Ability to Participate in PT (Full, Partial, None)
No participation
|
0 Participants
|
1 Participants
|
SECONDARY outcome
Timeframe: Post Operative Week 6Population: Data was unavailable for 1 participant in each group.
Subjective postoperative pain score at post operative week 6 of preoperative femoral nerve block plus postoperative continuous adductor canal nerve catheter compared to preoperative femoral nerve block plus postoperative saphenous nerve block using Subjective Numeric Pain Scale score with and without activity (on an 11 point scale when 0 is no pain and 10 is worst pain).
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=31 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=20 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
With activity · 0 (Pain on Subjective Numeric Pain Scale)
|
8 Participants
|
9 Participants
|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
With activity · 1 (Pain on Subjective Numeric Pain Scale)
|
5 Participants
|
1 Participants
|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
With activity · 2 (Pain on Subjective Numeric Pain Scale)
|
10 Participants
|
1 Participants
|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
With activity · 3 (Pain on Subjective Numeric Pain Scale)
|
3 Participants
|
3 Participants
|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
With activity · 4 (Pain on Subjective Numeric Pain Scale)
|
3 Participants
|
3 Participants
|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
With activity · 5 (Pain on Subjective Numeric Pain Scale)
|
2 Participants
|
3 Participants
|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
Without activity · 0 (Pain on Subjective Numeric Pain Scale)
|
22 Participants
|
14 Participants
|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
Without activity · 1 (Pain on Subjective Numeric Pain Scale)
|
4 Participants
|
4 Participants
|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
Without activity · 2 (Pain on Subjective Numeric Pain Scale)
|
2 Participants
|
1 Participants
|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
Without activity · 3 (Pain on Subjective Numeric Pain Scale)
|
2 Participants
|
1 Participants
|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
Without activity · 4 (Pain on Subjective Numeric Pain Scale)
|
1 Participants
|
0 Participants
|
|
Subjective Postoperative Pain Score at Post Operative Week 6 of Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
Without activity · 5 (Pain on Subjective Numeric Pain Scale)
|
0 Participants
|
0 Participants
|
SECONDARY outcome
Timeframe: Post Operative Week 6Population: Data was unavailable for 1 participant in each group.
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=31 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=20 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Evaluation of Ambulation at Post Operative Week 6 Assessing Independently vs Assistance, With or Without Pain
Unassisted with pain
|
6 Participants
|
6 Participants
|
|
Evaluation of Ambulation at Post Operative Week 6 Assessing Independently vs Assistance, With or Without Pain
Unassisted without pain
|
18 Participants
|
9 Participants
|
|
Evaluation of Ambulation at Post Operative Week 6 Assessing Independently vs Assistance, With or Without Pain
Assisted with pain
|
3 Participants
|
2 Participants
|
|
Evaluation of Ambulation at Post Operative Week 6 Assessing Independently vs Assistance, With or Without Pain
Assisted without pain
|
4 Participants
|
3 Participants
|
SECONDARY outcome
Timeframe: POD 1 following discharge from PACUPostoperative nausea and vomiting score on POD 1 following discharge from PACU
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=32 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=21 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Postoperative Nausea and Vomiting
No post operative nausea and vomiting
|
28 Participants
|
17 Participants
|
|
Postoperative Nausea and Vomiting
Yes post operative nausea and vomiting
|
4 Participants
|
4 Participants
|
SECONDARY outcome
Timeframe: Post Operative Week 6Population: Data was unavailable for 1 participant in each group.
Subjective assessment of experience with analgesia at post operative week 6 using rating of below expectations; met expectations; exceeded expectations
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=31 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=20 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Subjective Assessment of Experience With Analgesia
Below expectations
|
0 Participants
|
2 Participants
|
|
Subjective Assessment of Experience With Analgesia
Met expectations
|
13 Participants
|
7 Participants
|
|
Subjective Assessment of Experience With Analgesia
Exceeded expectations
|
18 Participants
|
11 Participants
|
SECONDARY outcome
Timeframe: Post Operative Day 3Population: Data was unavailable for 1 participant in the Long Acting Single Bolus Adductor Canal Nerve Block group on post operative day 3.
Subjective pain scores on POD 3 of patients receiving (1) preoperative femoral nerve block plus postoperative continuous adductor canal nerve catheter compared to (2) preoperative femoral nerve block plus postoperative saphenous nerve block using Subjective Numeric Pain Scale score (on an 11 point scale when 0 is no pain and 10 is worst pain).
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=32 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=20 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Subjective Pain Scores on POD 3 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
0 (Pain on Subjective Numeric Pain Scale)
|
2 Participants
|
2 Participants
|
|
Subjective Pain Scores on POD 3 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
1 (Pain on Subjective Numeric Pain Scale)
|
3 Participants
|
1 Participants
|
|
Subjective Pain Scores on POD 3 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
2 (Pain on Subjective Numeric Pain Scale)
|
8 Participants
|
2 Participants
|
|
Subjective Pain Scores on POD 3 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
3 (Pain on Subjective Numeric Pain Scale)
|
4 Participants
|
5 Participants
|
|
Subjective Pain Scores on POD 3 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
4 (Pain on Subjective Numeric Pain Scale)
|
6 Participants
|
1 Participants
|
|
Subjective Pain Scores on POD 3 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
5 (Pain on Subjective Numeric Pain Scale)
|
5 Participants
|
3 Participants
|
|
Subjective Pain Scores on POD 3 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
6 (Pain on Subjective Numeric Pain Scale)
|
2 Participants
|
3 Participants
|
|
Subjective Pain Scores on POD 3 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
7 (Pain on Subjective Numeric Pain Scale)
|
2 Participants
|
1 Participants
|
|
Subjective Pain Scores on POD 3 of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block
8 (Pain on Subjective Numeric Pain Scale)
|
0 Participants
|
2 Participants
|
SECONDARY outcome
Timeframe: Post Operative Day1Total postop opioid consumption measured by total pain pills on POD 1 of patients receiving (1) preoperative femoral nerve block plus postoperative continuous adductor canal nerve catheter compared to (2) preoperative femoral nerve block plus postoperative saphenous nerve block.
Outcome measures
| Measure |
Continuous Adductor Canal Nerve Catheter
n=32 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long- Acting Single Bolus Adductor Canal Nerve Block
n=21 Participants
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
0 pills
|
1 Participants
|
0 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
1 pill
|
1 Participants
|
0 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
2 pills
|
1 Participants
|
0 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
3 pills
|
3 Participants
|
2 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
4 pills
|
3 Participants
|
2 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
4.5 pills
|
0 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
5 pills
|
2 Participants
|
4 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
6 pills
|
8 Participants
|
6 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
7 pills
|
2 Participants
|
0 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
8 pills
|
7 Participants
|
3 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
10 pills
|
2 Participants
|
1 Participants
|
|
Total Postop Opioid Consumption of Patients Receiving (1) Preoperative Femoral Nerve Block Plus Postoperative Continuous Adductor Canal Nerve Catheter Compared to (2) Preoperative Femoral Nerve Block Plus Postoperative Saphenous Nerve Block.
12 pills
|
2 Participants
|
2 Participants
|
Adverse Events
Continuous Adductor Canal Nerve Catheter
Serious events: 0 serious events
Other events: 3 other events
Deaths: 0 deaths
Long Acting Single Bolus Adductor Canal Nerve Block
Serious events: 0 serious events
Other events: 4 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
| Measure |
Continuous Adductor Canal Nerve Catheter
n=34 participants at risk
Ultrasound guided femoral nerve block with 20cc of 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal continuous nerve catheter using normal saline bolus followed by 1/8% bupivacaine infusion through catheter at 8cc/h.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal continuous nerve catheter: Placement of ultrasound guided adductor canal continuous nerve catheter
Normal Saline as bolus followed by bupivacaine: normal
|
Long Acting Single Bolus Adductor Canal Nerve Block
n=23 participants at risk
Ultrasound guided femoral nerve block with 20cc 2% mepivacaine \<20 minutes prior to in room time. Intraoperative patients will undergo initiation of general anesthesia under the care of the attending anesthesiologist assigned to the patient. Induction will include a propofol bolus and placement of laryngeal mask airway. Intraoperative opioid should be limited to no more than 150mcg of fentanyl. Upon completion of wound closure, appropriate dressing placement, emergence from anesthesia and removal of LMA, patients to be taken to PACU. Once adequately awake and alert this group will receive ultrasound guided adductor canal nerve block with 10cc of 0.5% ropivacaine and 2 mg dexamethasone (0. 5cc), keeping total injectate at 10.5cc to spare significant proximal spread to femoral nerve.
Mepivacaine: 20cc of 2% mepivacaine \<20 minutes prior to in room time.
adductor canal nerve block: ultrasound guided adductor canal nerve block
ropivacaine and dexamethasone: 10cc of 0.5% ropiv
|
|---|---|---|
|
Surgical and medical procedures
Leaking from insertion site
|
5.9%
2/34 • Number of events 2 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
0.00%
0/23 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
|
Musculoskeletal and connective tissue disorders
Knee effusion
|
0.00%
0/34 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
8.7%
2/23 • Number of events 2 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
|
Gastrointestinal disorders
Inflamed esophagus
|
0.00%
0/34 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
4.3%
1/23 • Number of events 1 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
|
Gastrointestinal disorders
Heartburn
|
0.00%
0/34 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
4.3%
1/23 • Number of events 1 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
|
Gastrointestinal disorders
Nausea
|
0.00%
0/34 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
8.7%
2/23 • Number of events 2 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
|
Vascular disorders
Deep Vein Thrombosis
|
0.00%
0/34 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
4.3%
1/23 • Number of events 1 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
|
General disorders
Dizziness
|
2.9%
1/34 • Number of events 1 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
4.3%
1/23 • Number of events 1 • Time of consent to 6 weeks after surgery (6 weeks)
Complaints and symptoms not existing prior to consent
|
Additional Information
Christopher Sobey, MD
Vanderbilt University Medical Center
Phone: 615-322-4311
Email: [email protected]
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place