Trial Outcomes & Findings for Reducing HIV Risk Among Adolescents: Evaluating Project HEART (NCT NCT02579135)

NCT ID: NCT02579135

Last Updated: 2018-10-16

Results Overview

Program acceptability was assessed through a questionnaire that was adapted from prior acceptability surveys. Specifically, six items were included to assess six aspects of acceptability: (i) an intent to return to the website, (ii) whether one would recommend the program to a friend, (iii) whether one would use information from the program in the future, (iv) how much one liked the program, (v) how much one learned from the program and (vi) how much one felt the program kept their attention. The first three questions were coded with dichotomous response options (yes/no-unsure), whereas the last three items used a four point Likert-type scale ranging from 1=not at all to 4=a lot. For analyses, these last 3 items were dichotomized into 1=a lot and 0=not a lot.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

222 participants

Primary outcome timeframe

Immediate post-test at completion of intervention

Results posted on

2018-10-16

Participant Flow

Participant milestones

Participant milestones
Measure
Project HEART
Interactive website with five modules to address safer sex motivation, knowledge, attitudes/norms, self-efficacy, and sexual communication skills. Program takes approximately 30-45 minutes to complete. Safer Sex: Interactive web-based intervention with five modules: motivation, knowledge, attitudes/norms, self-efficacy, and sexual communication skills.
Control: Project Growing Minds
Attention-matched control website with five modules to address an introduction to mindsets, growth mindsets of intelligence, growth mindsets of self-control, growth mindsets of people, and an integrative summary. Program takes approximately 30-45 minutes to complete. Growth Mindsets: Interactive web-based intervention with five modules: mindsets introduction, growth mindsets of intelligence, growth mindsets of self-control, growth mindsets of people, and integrative summary.
Overall Study
STARTED
107
115
Overall Study
COMPLETED
105
106
Overall Study
NOT COMPLETED
2
9

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Reducing HIV Risk Among Adolescents: Evaluating Project HEART

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Project HEART
n=107 Participants
Interactive website with five modules to address safer sex motivation, knowledge, attitudes/norms, self-efficacy, and sexual communication skills. Program takes approximately 30-45 minutes to complete. Safer Sex: Interactive web-based intervention with five modules: motivation, knowledge, attitudes/norms, self-efficacy, and sexual communication skills.
Control: Project Growing Minds
n=115 Participants
Attention-matched control website with five modules to address an introduction to mindsets, growth mindsets of intelligence, growth mindsets of self-control, growth mindsets of people, and an integrative summary. Program takes approximately 30-45 minutes to complete. Growth Mindsets: Interactive web-based intervention with five modules: mindsets introduction, growth mindsets of intelligence, growth mindsets of self-control, growth mindsets of people, and integrative summary.
Total
n=222 Participants
Total of all reporting groups
Age, Continuous
15.26 years
STANDARD_DEVIATION .48 • n=5 Participants
15.22 years
STANDARD_DEVIATION .47 • n=7 Participants
15.24 years
STANDARD_DEVIATION .48 • n=5 Participants
Sex: Female, Male
Female
107 Participants
n=5 Participants
115 Participants
n=7 Participants
222 Participants
n=5 Participants
Sex: Female, Male
Male
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race/Ethnicity, Customized
White/Non-Hispanic
38 Participants
n=5 Participants
45 Participants
n=7 Participants
83 Participants
n=5 Participants
Race/Ethnicity, Customized
Black/Non-Hispanic
29 Participants
n=5 Participants
25 Participants
n=7 Participants
54 Participants
n=5 Participants
Race/Ethnicity, Customized
Hispanic
31 Participants
n=5 Participants
34 Participants
n=7 Participants
65 Participants
n=5 Participants
Race/Ethnicity, Customized
Other/Mixed Race-Ethnicity
9 Participants
n=5 Participants
11 Participants
n=7 Participants
20 Participants
n=5 Participants
Region of Enrollment
United States
107 Participants
n=5 Participants
115 Participants
n=7 Participants
222 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Immediate post-test at completion of intervention

Population: Data on acceptability only analyzed among girls who completed the Project HEART intervention

Program acceptability was assessed through a questionnaire that was adapted from prior acceptability surveys. Specifically, six items were included to assess six aspects of acceptability: (i) an intent to return to the website, (ii) whether one would recommend the program to a friend, (iii) whether one would use information from the program in the future, (iv) how much one liked the program, (v) how much one learned from the program and (vi) how much one felt the program kept their attention. The first three questions were coded with dichotomous response options (yes/no-unsure), whereas the last three items used a four point Likert-type scale ranging from 1=not at all to 4=a lot. For analyses, these last 3 items were dichotomized into 1=a lot and 0=not a lot.

Outcome measures

Outcome measures
Measure
Project HEART
n=107 Participants
Interactive website with five modules to address safer sex motivation, knowledge, attitudes/norms, self-efficacy, and sexual communication skills. Program takes approximately 30-45 minutes to complete. Safer Sex: Interactive web-based intervention with five modules: motivation, knowledge, attitudes/norms, self-efficacy, and sexual communication skills.
Control: Project Growing Minds
Attention-matched control website with five modules to address an introduction to mindsets, growth mindsets of intelligence, growth mindsets of self-control, growth mindsets of people, and an integrative summary. Program takes approximately 30-45 minutes to complete. Growth Mindsets: Interactive web-based intervention with five modules: mindsets introduction, growth mindsets of intelligence, growth mindsets of self-control, growth mindsets of people, and integrative summary.
6-item Self-report of Program Acceptability
Would return to site
84 Participants
6-item Self-report of Program Acceptability
Recommend to friend
94 Participants
6-item Self-report of Program Acceptability
Use Information in Future
101 Participants
6-item Self-report of Program Acceptability
Liked program a lot
60 Participants
6-item Self-report of Program Acceptability
Learned a lot
80 Participants
6-item Self-report of Program Acceptability
Program kept attention a lot
69 Participants

PRIMARY outcome

Timeframe: Immediate post-test at completion of intervention and 3-month follow-up

We used the validated Self-Efficacy for HIV Prevention Scale to assess communication self-efficacy. Seven items assessed confidence communicating about sexual topics (e.g., "How sure are you that you could talk to your partner about safer sex?"). Participants responded from 1 for "couldn't do it" to 4 for "very sure." Scores were averaged with higher scores indicating greater confidence in communicating about sex (alpha = 0.82).

Outcome measures

Outcome measures
Measure
Project HEART
n=107 Participants
Interactive website with five modules to address safer sex motivation, knowledge, attitudes/norms, self-efficacy, and sexual communication skills. Program takes approximately 30-45 minutes to complete. Safer Sex: Interactive web-based intervention with five modules: motivation, knowledge, attitudes/norms, self-efficacy, and sexual communication skills.
Control: Project Growing Minds
n=114 Participants
Attention-matched control website with five modules to address an introduction to mindsets, growth mindsets of intelligence, growth mindsets of self-control, growth mindsets of people, and an integrative summary. Program takes approximately 30-45 minutes to complete. Growth Mindsets: Interactive web-based intervention with five modules: mindsets introduction, growth mindsets of intelligence, growth mindsets of self-control, growth mindsets of people, and integrative summary.
7-item Self-report of Sexual Communication Self-efficacy
3.62 units on a scale
Standard Deviation .47
3.51 units on a scale
Standard Deviation .46

PRIMARY outcome

Timeframe: Immediate post-test at completion of intervention and 3-month follow-up

We assessed intentions to communicate about sex with items from the AIDS Risk Behavior Assessment. Three items captured the likelihood of communicating with a partner in the next 3 months about (1) sexual limits and boundaries, (2) STDs and pregnancy, and (3) condom use. Options ranged from 0% to 100% to indicate the likelihood of communicating with a partner. We averaged scores to create a composite (possible range 0-100); higher scores indicated greater likelihood of sexual communication (alpha = 0.84).

Outcome measures

Outcome measures
Measure
Project HEART
n=107 Participants
Interactive website with five modules to address safer sex motivation, knowledge, attitudes/norms, self-efficacy, and sexual communication skills. Program takes approximately 30-45 minutes to complete. Safer Sex: Interactive web-based intervention with five modules: motivation, knowledge, attitudes/norms, self-efficacy, and sexual communication skills.
Control: Project Growing Minds
n=114 Participants
Attention-matched control website with five modules to address an introduction to mindsets, growth mindsets of intelligence, growth mindsets of self-control, growth mindsets of people, and an integrative summary. Program takes approximately 30-45 minutes to complete. Growth Mindsets: Interactive web-based intervention with five modules: mindsets introduction, growth mindsets of intelligence, growth mindsets of self-control, growth mindsets of people, and integrative summary.
3-item Self-report of Sexual Communication Intentions Over Next 3 Months
87.0 units on a scale
Standard Deviation 22.5
78.5 units on a scale
Standard Deviation 27.9

Adverse Events

Project HEART

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control: Project Growing Minds

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Laura Widman

North Carolina State University

Phone: 919-513-2546

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place