The PROspective German NOn-CF bronchiectaSIS Patient Registry

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

750 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-07-31

Study Completion Date

2021-07-31

Brief Summary

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The purpose of this study is to study the epidemiology of non-CF bronchiectasis (NCFB) and to provide an estimate of the distribution (prevalence) of NCFB etiologies across all different levels of health care as well as real-life data regarding the current management of NCFB in Germany.

Detailed Description

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* To study the epidemiology of non-CF bronchiectasis (NCFB) and to provide an estimate of the distribution (prevalence) of NCFB etiologies across all different levels of health care as well as real-life data regarding the current management of NCFB in Germany
* To establish feasible investigational strategies in order to establish the etiology of NCFB
* To perform observational research into bronchiectasis, particularly in areas where single center datasets are underpowered, such as in rare etiologies or determining markers of prognosis
* To promote collaborative clinical, basic and translational research in NCFB between German (and European) centers
* To provide a registry of well phenotyped patients with NCFB in clinical centers potentially eligible for enrolment into clinical trials
* To track access to healthcare and cost of caring for patients with NCFB over time

Conditions

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Bronchiectasis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* A clinical history consistent with bronchiectasis
* (High resolution) computed tomography (CT) scan of the chest demonstrating bronchiectasis affecting 1 or more lobes

Exclusion Criteria

* Bronchiectasis due to known cystic fibrosis (CF)
* Age \<18 years
* Interstitial lung disease
* Prior lung or heart-lung transplantation

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jessica Rademacher

Role: STUDY_CHAIR

CAPNETZ STIFTUNG; Medizinische Hochschule Hannover

Felix C. Ringshausen

Role: STUDY_CHAIR

CAPNETZ STIFTUNG; Medizinische Hochschule Hannover

Andrés de Roux

Role: STUDY_CHAIR

Pneumologische Praxis Berlin

Locations

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