Trial Outcomes & Findings for Home-Based Health Management of COPD Patients (NCT NCT02557178)

NCT ID: NCT02557178

Last Updated: 2021-02-24

Results Overview

Number of daily steps as measured by the SenseWear Pro ArmBand, which is an accepted criterion measure for daily physical activity in adults with Chronic Obstructive Pulmonary Disease.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

154 participants

Primary outcome timeframe

Steps measured at baseline (week 1) and week 9

Results posted on

2021-02-24

Participant Flow

2 controls off study before completing baseline forms or phone calls (1 withdrew and 1 lost to follow up) 6 intervention participants off study before completing baseline forms or phone calls (5 withdrew and 1 lost to follow up)

Participant milestones

Participant milestones
Measure
Activity Monitor Plus Health Coaching
Device: Actigraph Participants will wear the device daily during weeks 1, 9, and 17. Daily steps and activity will be measured. It will identify if they complete a prescribed exercise regimen. Participants in the intervention condition (wearing the Actigraph) will also receive supportive health coaching to encourage them to exercise. health coaching: Supportive coaching to encourage compliance with prescribed pulmonary rehabilitation.
Control
Device: Actigraph Participants will wear the device daily during weeks 1, 9, and 17. Daily steps and activity will be measured. It will identify if they complete a prescribed exercise regimen.
Overall Study
STARTED
72
74
Overall Study
COMPLETED
56
63
Overall Study
NOT COMPLETED
16
11

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Home-Based Health Management of COPD Patients

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Activity Monitor Plus Health Coaching
n=72 Participants
Device: Actigraph Participants will wear the device daily during weeks 1, 9, and 17. Daily steps and activity will be measured. It will identify if they complete a prescribed exercise regimen. Participants in the intervention condition (wearing the Actigraph) will also receive supportive health coaching to encourage them to exercise. health coaching: Supportive coaching to encourage compliance with prescribed pulmonary rehabilitation.
Control
n=74 Participants
Device: Actigraph Participants will wear the device daily during weeks 1, 9, and 17. Daily steps and activity will be measured. It will identify if they complete a prescribed exercise regimen.
Total
n=146 Participants
Total of all reporting groups
Age, Continuous
69.4 years
STANDARD_DEVIATION 8.1 • n=93 Participants
68.5 years
STANDARD_DEVIATION 9.1 • n=4 Participants
68.9 years
STANDARD_DEVIATION 8.6 • n=27 Participants
Sex: Female, Male
Female
38 Participants
n=93 Participants
37 Participants
n=4 Participants
75 Participants
n=27 Participants
Sex: Female, Male
Male
34 Participants
n=93 Participants
37 Participants
n=4 Participants
71 Participants
n=27 Participants
Race (NIH/OMB)
American Indian or Alaska Native
1 Participants
n=93 Participants
0 Participants
n=4 Participants
1 Participants
n=27 Participants
Race (NIH/OMB)
Asian
0 Participants
n=93 Participants
0 Participants
n=4 Participants
0 Participants
n=27 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=93 Participants
0 Participants
n=4 Participants
0 Participants
n=27 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=93 Participants
1 Participants
n=4 Participants
1 Participants
n=27 Participants
Race (NIH/OMB)
White
70 Participants
n=93 Participants
73 Participants
n=4 Participants
143 Participants
n=27 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=93 Participants
0 Participants
n=4 Participants
0 Participants
n=27 Participants
Race (NIH/OMB)
Unknown or Not Reported
1 Participants
n=93 Participants
0 Participants
n=4 Participants
1 Participants
n=27 Participants
Physical Activity from ActiGraph
3547.3 steps
STANDARD_DEVIATION 1835.8 • n=93 Participants
4426.3 steps
STANDARD_DEVIATION 2628.3 • n=4 Participants
4016.1 steps
STANDARD_DEVIATION 2326.7 • n=27 Participants
Quality of Life Physical Summary
4.3 units on a scale
STANDARD_DEVIATION 1.2 • n=93 Participants
4.2 units on a scale
STANDARD_DEVIATION 1.1 • n=4 Participants
4.2 units on a scale
STANDARD_DEVIATION 1.2 • n=27 Participants

PRIMARY outcome

Timeframe: Steps measured at baseline (week 1) and week 9

Population: Data is provided for 119 participants who completed the study.

Number of daily steps as measured by the SenseWear Pro ArmBand, which is an accepted criterion measure for daily physical activity in adults with Chronic Obstructive Pulmonary Disease.

Outcome measures

Outcome measures
Measure
Activity Monitor Plus Health Coaching
n=56 Participants
Device: Actigraph Participants will wear the device daily during weeks 1, 9, and 17. Daily steps and activity will be measured. It will identify if they complete a prescribed exercise regimen. Participants in the intervention condition (wearing the Actigraph) will also receive supportive health coaching to encourage them to exercise. health coaching: Supportive coaching to encourage compliance with prescribed pulmonary rehabilitation.
Control
n=63 Participants
Device: Actigraph Participants will wear the device daily during weeks 1, 9, and 17. Daily steps and activity will be measured. It will identify if they complete a prescribed exercise regimen.
Change in Number of Daily Steps Between the Intervention and Control Conditions
-344.8 steps
Standard Deviation 1657.7
-975.8 steps
Standard Deviation 2596.3

PRIMARY outcome

Timeframe: Quality of Life measured at baseline (week 1) and week 9

Population: Data is provided for 119 participants who completed the study.

Measure Description: The Chronic Respiratory Disease Questionnaire measures physical and emotional aspects with 20 items in four domains/categories. The two domains/categories used for physical summary were dyspnea and fatigue. The items are assessed numerically on a 7-point modified Likert scale (from 1 to 7). Scores are obtained by adding the scores for the items that make up each category and dividing by the number of items. Physical quality of life is obtained by adding the fatigue and dyspnea scores and dividing by two; hence, the score range is from 1 to 7. Higher scores indicate better health-related quality of life. Scores are obtained by adding the scores for the items that make up each category and dividing by the number of items. A minimally important difference is a change in score of 0.5 or more.

Outcome measures

Outcome measures
Measure
Activity Monitor Plus Health Coaching
n=56 Participants
Device: Actigraph Participants will wear the device daily during weeks 1, 9, and 17. Daily steps and activity will be measured. It will identify if they complete a prescribed exercise regimen. Participants in the intervention condition (wearing the Actigraph) will also receive supportive health coaching to encourage them to exercise. health coaching: Supportive coaching to encourage compliance with prescribed pulmonary rehabilitation.
Control
n=63 Participants
Device: Actigraph Participants will wear the device daily during weeks 1, 9, and 17. Daily steps and activity will be measured. It will identify if they complete a prescribed exercise regimen.
Change in Physical Quality of Life Between the Intervention and Control Conditions
0.2 units on a scale
Standard Deviation 1.0
0.0 units on a scale
Standard Deviation 0.7

Adverse Events

Activity Monitor Plus Health Coaching

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Johanna Hoult

Mayo Clinic

Phone: 507-293-1989

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place