Predicted Level of General Anaesthesia in Hip Fracture Surgery

NCT ID: NCT02556658

Last Updated: 2020-11-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-02-28

Study Completion Date

2016-04-30

Brief Summary

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The purpose of this study is to evaluate if prediction of general anaesthesia level by the Smartpilot® View device can improve the quality of anaesthesia in patients undergoing hip fracture surgery.

Detailed Description

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Conditions

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Hip Fracture Surgery

Keywords

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Smartpilot View Hip fracture surgery Depth of anaesthesia Intraoperative hypotension Quality of anaesthesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Smartpilot View group

General anaesthesia managed by the Smartpilot® View device The intervention consists of administering hypnotics and opioids according to effect-site concentrations and interaction model provided by the Smartpilot® View software for the entire duration of general anaesthesia.

Group Type EXPERIMENTAL

General anesthesia managed by the Smartpilot® View

Intervention Type DEVICE

General anaesthesia managed by the Smartpilot® View device The intervention consists of administering hypnotics and opioids according to effect-site concentrations and interaction model provided by the Smartpilot® View software for the entire duration of general anaesthesia.

Control group

General anaesthesia without using the Smartpilot® View device The anesthetic induction will be performed by propofol or sufentanil and atracurium. The maintenance of anesthesia will be directed by desflurane and sufentanil. The dosages of anesthetics are left to the discretion of the doctor and nurse anesthetists in charge of the patient in the operating room.

Group Type ACTIVE_COMPARATOR

General anesthesia managed without the Smartpilot® View

Intervention Type DEVICE

General anaesthesia without using the Smartpilot® View device The anesthetic induction will be performed by propofol or sufentanil and atracurium. The maintenance of anesthesia will be directed by desflurane and sufentanil. The dosages of anesthetics are left to the discretion of the doctor and nurse anesthetists in charge of the patient in the operating room.

Interventions

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General anesthesia managed by the Smartpilot® View

General anaesthesia managed by the Smartpilot® View device The intervention consists of administering hypnotics and opioids according to effect-site concentrations and interaction model provided by the Smartpilot® View software for the entire duration of general anaesthesia.

Intervention Type DEVICE

General anesthesia managed without the Smartpilot® View

General anaesthesia without using the Smartpilot® View device The anesthetic induction will be performed by propofol or sufentanil and atracurium. The maintenance of anesthesia will be directed by desflurane and sufentanil. The dosages of anesthetics are left to the discretion of the doctor and nurse anesthetists in charge of the patient in the operating room.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient undergoing hip fracture surgery under general anaesthesia
* Age ≥ 18 years old
* ASA classification 1, 2 or 3

Exclusion Criteria

* Patient not insured by a social security scheme
* Adult patient under tutorship or curatorship
* Age over 18 years old or under 90 years old
* Weight under 40 or over 140 kilos and/or height under 150 or over 200 cm
* Body mass index \> 35
* Contraindication to one or more anaesthetics used in the study
* Pregnancy or breastfeeding
* Unweaned alcoholism
* ASA classification 4 or 5
* Patient undergoing hip fracture surgery under spinal anaesthesia
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Angers

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mathieu CONTE, M.D.

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Angers

Locations

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University Hospital Angers

Angers, , France

Site Status

Countries

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France

References

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Leblanc D, Conte M, Masson G, Richard F, Jeanneteau A, Bouhours G, Chretien JM, Rony L, Rineau E, Lasocki S. SmartPilot(R) view-guided anaesthesia improves postoperative outcomes in hip fracture surgery: a randomized blinded controlled study. Br J Anaesth. 2017 Nov 1;119(5):1022-1029. doi: 10.1093/bja/aex317.

Reference Type RESULT
PMID: 29028921 (View on PubMed)

Other Identifiers

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2014-A01243-44

Identifier Type: -

Identifier Source: org_study_id