An Observational Study in Patients With Breast Cancer and Bone Metastases Receiving Ibandronate (Bondronat)

NCT ID: NCT02553850

Last Updated: 2016-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

442 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-04-30

Study Completion Date

2010-01-31

Brief Summary

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This open non-randomized, single-arm, multicenter, observational study is designed to evaluate the correlation between bone turnover markers and the response to treatment in patients with breast cancer and bone metastases. In this observational study, ibandronate (Bondronat) will be prescribed and used in accordance with the standards of care. Data will be collected for 12 months.

Detailed Description

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Conditions

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Breast Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Ibandronate

Patients receiving ibandronate will be evaluated for bone turnover markers for 12 months. Ibandronate is not an investigational medicinal product (IMP) in this study.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* All criteria in accordance with the Summary of Product Characteristics of Bondronat (ibandronate)
* Adult patients greater than (\>) 18 years of age
* Histologically confirmed breast cancer
* Confirmed bone metastasis (by bone scintigraphy, X-ray, computed tomography or magnetic resonance imaging)
* Life expectancy \>6 months
* No previous bisphosphonate therapy
* Patients signed written informed consent form before study start

Exclusion Criteria

* All criteria in accordance with the Summary of Product Characteristics of Bondronat(ibandronate)
* Hypersensitivity to the active substance or any of the excipients of Bondronat (ibandronate)
* Hypersensitivity to bisphosphonates
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hoffmann-La Roche

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clinical Trials

Role: STUDY_DIRECTOR

Hoffmann-La Roche

Locations

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Budapest, , Hungary

Site Status

Budapest, , Hungary

Site Status

Budapest, , Hungary

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Budapest, , Hungary

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Debrecen, , Hungary

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Győr, , Hungary

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Gyula, , Hungary

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Kaposvár, , Hungary

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Nyíregyháza, , Hungary

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Pécs, , Hungary

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Szeged, , Hungary

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Szeged, , Hungary

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Szekszárd, , Hungary

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Székesfehérvár, , Hungary

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Szolnok, , Hungary

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Szombathely, , Hungary

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Tatabánya, , Hungary

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Veszprém, , Hungary

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Zalaegerszeg-Pozva, , Hungary

Site Status

Countries

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Hungary

Other Identifiers

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ML20416

Identifier Type: -

Identifier Source: org_study_id