Caregiver Burden of Wet Age-related Macular Degeneration (wAMD) in Japan

NCT ID: NCT02541084

Last Updated: 2017-08-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

72 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-08-18

Study Completion Date

2016-07-30

Brief Summary

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This study aims at investigation of the caregiver burden of Wet Age-related Macular Degeneration (wAMD) patients and at the assessment of how much of caregiver burden could be reduced in transitioning from Pro Re Nata to proactive therapy especially in real-life rural settings where public transportations are not readily available.

Detailed Description

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Conditions

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Wet Macular Degeneration

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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PRN group

wAMD-patients treated with anti-VEGF therapy ´pro re nata´ (PRN)

Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)

Intervention Type DRUG

Anti-VEGF therapy following the Summary of Product Characteristics

TAE group

wAMD-patients treated with anti-VEGF therapy ´treat-and-extend´ (TAE)

Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)

Intervention Type DRUG

Anti-VEGF therapy following the Summary of Product Characteristics

PRN-to-TAE switcher group

wAMD patients treated with anti-VEGF therapy and switching from PRN to TAE regimens

Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)

Intervention Type DRUG

Anti-VEGF therapy following the Summary of Product Characteristics

Interventions

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Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)

Anti-VEGF therapy following the Summary of Product Characteristics

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* \[Patients\]

* Female and male out-patients diagnosed with wAMD.
* Patients who are accompanied by his/her caregiver(s).
* Patients who have been receiving anti-VEGF therapy with proactive regimen for 12 months or more at the participating site.
* Providing informed consent for the participation in this study.
* \[Caregivers\]

* Providing informed consent for the participation in this study.
* Capable of understanding and completing the questionnaires without any help from others

Exclusion Criteria

* \[Patients\]

* Presence of a disease or a condition more disabling than wAMD in term of caregiving.
* Presence of intractable neurologic disease, physical handicap, mental handicap, or any condition that rendered them unable to walk independently.
* Intraocular surgery for other eye diseases after the start of wAMD therapy.
* \[Caregivers\]

* Professional carers
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Regeneron Pharmaceuticals

INDUSTRY

Sponsor Role collaborator

Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Many Locations, , Japan

Site Status

Countries

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Japan

Other Identifiers

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17945

Identifier Type: -

Identifier Source: org_study_id

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