Evaluation of Inner Ear and Brain Structures With Contrast-enhanced MRI in Healthy Subjects (HYDROPS)
NCT ID: NCT02529475
Last Updated: 2020-11-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
PHASE4
25 participants
INTERVENTIONAL
2016-02-01
2020-09-30
Brief Summary
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* MR Perfusion Imaging will be assess in both cochlea as well
* Primary auditory brain pathways will be evaluated through MR diffusion imaging
Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Gadoteric acid
Gadoteric acid 0.2 mmol/kg
Gadoteric acid
Comparison with patients with Meniere's disease
Interventions
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Gadoteric acid
Comparison with patients with Meniere's disease
Eligibility Criteria
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Inclusion Criteria
* Informed consent signed
* Medical examination performed prior to participation in research
* Patients without history of inner ear disease
* Recipient of a French social security scheme
Exclusion Criteria
* Patients on a legal protection regime type guardianship
* Respiratory pathologies, cardiovascular, renal, diabetes
* Claustrophobia
* Contraindications to exposure to a magnetic field
* Contraindications to injecting Dotarem ®
40 Years
ALL
Yes
Sponsors
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University Hospital, Grenoble
OTHER
Responsible Party
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Principal Investigators
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Arnaud ATTYE, PH
Role: PRINCIPAL_INVESTIGATOR
University Hospital, Grenoble
Locations
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GrenobleUniversityHospital
Grenoble, , France
Hôpital Lariboisière
Paris, , France
Hôpital Charles Nicolle
Rouen, , France
Countries
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References
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Eliezer M, Maquet C, Horion J, Gillibert A, Toupet M, Bolognini B, Magne N, Kahn L, Hautefort C, Attye A. Detection of intralabyrinthine abnormalities using post-contrast delayed 3D-FLAIR MRI sequences in patients with acute vestibular syndrome. Eur Radiol. 2019 Jun;29(6):2760-2769. doi: 10.1007/s00330-018-5825-0. Epub 2018 Nov 9.
Other Identifiers
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38RC14.428
Identifier Type: -
Identifier Source: org_study_id